Paper5778667

An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.

Schroeder WA and 2 others. Arch Biochem Biophys, 1969. Cited by 275 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase. Papers, record 5778667. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/5778667

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.; PubMed
Journal: Arch Biochem Biophys; PubMed
Year: 1969; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/5778667/; PubMed
DOI: https://doi.org/10.1016/0003-9861(69)90069-1; PubMed
The journal: https://conductscience.org/library/journal-index/0372430; PubMed
Citations, by iCite: 275; iCite
Revised in PubMed: 2019-06-29; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Schroeder WA	W A
2	Shelton JB	J B
3	Shelton JR	J R

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Bromine	Major topic
Catalase	Major topic
Cyanides	Major topic
Amino Acids
Countercurrent Distribution
Fluoroacetates
Formates
Kinetics
Methionine
Methods
Serine
Threonine

Source PubMed

Show 6 more topicsShow fewer topics

Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 275 citations.

PMID	Title	Journal	Year	In Papers	Source
42,370,303	Protein digestion using a cysteine-specific backbone cleavage reagent.	RSC Chem Biol	2026	https://conductscience.org/library/papers/42370303	PubMed
28,451,301	Room temperature decarboxylative cyanation of carboxylic acids using photoredox catalysis and cyanobenziodoxolones: a divergent mechanism compared to alkynylation.	Chem Sci	2017	https://conductscience.org/library/papers/28451301	PubMed
23,123,196	EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.	Mol Cell	2012	https://conductscience.org/library/papers/23123196	PubMed
21,856,844	Specificity and role of the Borrelia burgdorferi CtpA protease in outer membrane protein processing.	J Bacteriol	2011	https://conductscience.org/library/papers/21856844	PubMed
18,811,218	Rapid microwave-assisted CNBr cleavage of bead-bound peptides.	J Comb Chem	2008	https://conductscience.org/library/papers/18811218	PubMed
8,702,264	Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.	Appl Environ Microbiol	1996	https://conductscience.org/library/papers/8702264	PubMed
8,595,261	Alliinase (alliin lyase) from garlic (Alliium sativum) is glycosylated at ASN146 and forms a complex with a garlic mannose-specific lectin.	Glycoconj J	1995	https://conductscience.org/library/papers/8595261	PubMed
7,092,811	Isolation, characterization and N-terminal sequences of the CNBr-cleavage peptides from human complement Factor B. Localization of a free thiol group and a sequence defining the site cleaved by factor D.	Biochem J	1982	https://conductscience.org/library/papers/7092811	PubMed
7,044,306	Genetic and biochemical characterization of an Escherichia coli K-12 mutant with an altered outer membrane protein.	Antonie Van Leeuwenhoek	1981	https://conductscience.org/library/papers/7044306	PubMed
6,795,632	Primary structure of porcine heart citrate synthase.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6795632	PubMed
6,766,438	Chemical analysis of major outer membrane proteins of Neisseria meningitidis: comparison of serotypes 2 and 11.	J Bacteriol	1980	https://conductscience.org/library/papers/6766438	PubMed
6,604,521	Methionine in rabbit alpha 1-proteinase inhibitors.	Biochem J	1983	https://conductscience.org/library/papers/6604521	PubMed
6,370,231	Sequence variability in the retinal-attachment domain of mammalian rhodopsins.	Biochem J	1984	https://conductscience.org/library/papers/6370231	PubMed
6,342,609	Amino acid sequence of the Bb fragment from human complement Factor B. Alignment of the cyanogen bromide-cleavage peptides.	Biochem J	1983	https://conductscience.org/library/papers/6342609	PubMed
6,330,671	Blood coagulation factor X mRNA encodes a single polypeptide chain containing a prepro leader sequence.	Nucleic Acids Res	1984	https://conductscience.org/library/papers/6330671	PubMed
6,224,479	Isolation and characterization of the CNBr peptides from the proteolytically derived N-terminal fragment of ovine opsin.	Biochem J	1983	https://conductscience.org/library/papers/6224479	PubMed
6,203,098	Isolation of cDNA and genomic DNA clones encoding type II collagen.	Nucleic Acids Res	1984	https://conductscience.org/library/papers/6203098	PubMed
6,130,060	Properties of pili from Escherichia coli SS142 that mediate mannose-resistant adhesion to mammalian cells.	J Bacteriol	1983	https://conductscience.org/library/papers/6130060	PubMed
5,289,018	Bovine liver glutamate dehydrogenase: tentative amino acid sequence; identification of a reactive lysine; nitration of a specific tyrosine and loss of allosteric inhibition by guanosine triphosphate.	Proc Natl Acad Sci U S A	1970	https://conductscience.org/library/papers/5289018	PubMed
5,168,302	The determination of methionine by gas-liquid chromatography.	Biochem J	1971	https://conductscience.org/library/papers/5168302	PubMed

Show 14 more cited byShow fewer cited bySee all 36 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
CAT	847	PubTator's text mining	https://conductscience.org/library/genes/847

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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