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Paper7092811

Isolation, characterization and N-terminal sequences of the CNBr-cleavage peptides from human complement Factor B. Localization of a free thiol group and a sequence defining the site cleaved by factor D.

Christie DL and 1 other. Biochem J, 1982. Cited by 35 papers, by iCite.

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ConductScience Library. Isolation, characterization and N-terminal sequences of the CNBr-cleavage peptides from human complement Factor B. Localization of a free thiol group and a sequence defining the site cleaved by factor D. Papers, record 7092811. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7092811

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Isolation, characterization and N-terminal sequences of the CNBr-cleavage peptides from human complement Factor B. Localization of a free thiol group and a sequence defining the site cleaved by factor D.
PubMed
Journal
Biochem J
PubMed
Year
1982
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
35
iCite
Relative citation ratio, by iCite
0.95
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Christie DLD L
2Gagnon JJ

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Complement Activating EnzymesMajor topic
Peptide FragmentsMajor topic
Amino Acid Sequence
Amino Acids
Amino Sugars
Chromatography, Gel
Chromatography, High Pressure Liquid
Cyanogen Bromide
Humans
Sulfhydryl Compounds

Source PubMed

References26

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,227,961The quantitation of glucosamine and galactosamine in glycoproteins after hydrolysis in p-toluenesulphonic acid.FEBS Lett1975https://conductscience.org/library/papers/1227961PubMed
25,432,063Cleavage of structural proteins during the assembly of the head of bacteriophage T4.Nature1970https://conductscience.org/library/papers/5432063PubMed
3458,145The alternative pathway C3/C5 convertase: chemical basis of factor B activation.J Immunol1979https://conductscience.org/library/papers/458145PubMed
4786,150Comparative aspects of glycoprotein structure.Annu Rev Biochem1976https://conductscience.org/library/papers/786150PubMed
56,997,298Structural evidence that complement factor B constitutes a novel class of serine protease.J Biol Chem1980https://conductscience.org/library/papers/6997298PubMed
6261,515Limited proteolysis of complement components C2 and factor B. Structural analogy and limited sequence homology.Biochem J1979https://conductscience.org/library/papers/261515PubMed
7667,015Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.Biochemistry1978https://conductscience.org/library/papers/667015PubMed
81,006,167The serine protease nature of the C3 and C5 convertases of the classical and alternative complement pathways.Scand J Immunol1976https://conductscience.org/library/papers/1006167PubMed
9352,622A molecular approach to the complement system.Curr Top Cell Regul1978https://conductscience.org/library/papers/352622PubMed
106,769,474Amino-terminal sequence of human factor B of the alternative complement pathway and its cleavage fragments, Ba and Bb.Biochemistry1980https://conductscience.org/library/papers/6769474PubMed
11728,424Sequence of the amino-terminal 349 residues of rabbit muscle glycogen phosphorylase including the sites of covalent and allosteric control.Biochemistry1978https://conductscience.org/library/papers/728424PubMed
125,093,780Functional relationship of factor B in the properdin system to C3 proactivator of human serum.J Immunol1971https://conductscience.org/library/papers/5093780PubMed
135,778,667An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.Arch Biochem Biophys1969https://conductscience.org/library/papers/5778667PubMed
146,821,372
Factor D of the alternative pathway of human complement. Purification, alignment and N-terminal amino acid sequences of the major cyanogen bromide fragments, and localization of the serine residue at the active site.
Biochem J1980https://conductscience.org/library/papers/6821372PubMed
167,258,621Use of fluorescamine as an effective blocking reagent to reduce the background in protein sequence analyses by the Beckman automated sequencer.Anal Biochem1981https://conductscience.org/library/papers/7258621PubMed
175,499,437Isolation and properties of a glycine-rich beta-glycoprotein of human serum.Biochim Biophys Acta1970https://conductscience.org/library/papers/5499437PubMed
18417,728The purification and properties of the second component of human complement.Biochem J1978https://conductscience.org/library/papers/417728PubMed
19411,505Chemical characterization of human factor B of the alternate pathway of complement activation.Biochemistry1977https://conductscience.org/library/papers/411505PubMed
20488,920A cheap and simple method to achieve and maintain the necessary purity of reagents and solvents for automated amino acid sequence determination with the sequenator.Hoppe Seylers Z Physiol Chem1979https://conductscience.org/library/papers/488920PubMed
217,023,363The proteolytic activation systems of complement.Annu Rev Biochem1981https://conductscience.org/library/papers/7023363PubMed

See all 26 references

Cited by15

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 35 citations.

PMIDTitleJournalYearIn PapersSource
7,103,942Purification of human C3b inactivator by monoclonal-antibody affinity chromatography.Biochem J1982https://conductscience.org/library/papers/7103942PubMed
6,555,044
The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N-terminal amino acid sequence of a peptide from C2a containing a free thiol group.
Biochem J1983https://conductscience.org/library/papers/6555044PubMed
6,526,007PC13 embryonal carcinoma-derived growth factor.EMBO J1984https://conductscience.org/library/papers/6526007PubMed
6,342,610Amino acid sequence of the Bb fragment from complement Factor B. Sequence of the major cyanogen bromide-cleavage peptide (CB-II) and completion of the sequence of the Bb fragment.Biochem J1983https://conductscience.org/library/papers/6342610PubMed
6,342,609Amino acid sequence of the Bb fragment from human complement Factor B. Alignment of the cyanogen bromide-cleavage peptides.Biochem J1983https://conductscience.org/library/papers/6342609PubMed
6,323,161Internal homologies of the Ba fragment from human complement component Factor B, a class III MHC antigen.EMBO J1984https://conductscience.org/library/papers/6323161PubMed
3,036,070Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r.Biochem J1987https://conductscience.org/library/papers/3036070PubMed
3,030,276Chemical modification of the haem propionate of cytochrome c. A re-evaluation of the reaction of cytochrome c with a water-soluble carbodi-imide.Biochem J1986https://conductscience.org/library/papers/3030276PubMed
2,983,658Primary structure of the A chain of human complement-classical-pathway enzyme C1r. N-terminal sequences and alignment of autolytic fragments and CNBr-cleavage peptides.Biochem J1985https://conductscience.org/library/papers/2983658PubMed
2,963,625The complete amino acid sequence of human complement factor H.Biochem J1988https://conductscience.org/library/papers/2963625PubMed
2,962,936Sequence polymorphism of human complement factor H.Immunogenetics1988https://conductscience.org/library/papers/2962936PubMed
2,954,816The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor.EMBO J1987https://conductscience.org/library/papers/2954816PubMed
2,951,479Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.J Exp Med1987https://conductscience.org/library/papers/2951479PubMed
2,937,401CNBr cleavage of the light chain of human complement factor I and alignment of the fragments.Biochem J1986https://conductscience.org/library/papers/2937401PubMed
2,829,834The effects of autolysis on the structure of chicken calpain II.Biochem J1987https://conductscience.org/library/papers/2829834PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
CFB629PubTator's text mininghttps://conductscience.org/library/genes/629

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • ClinicalTrials.govNo license stated
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  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
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  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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