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Paper · 591002

Dimethyl diotadecyl ammonium bromide as adjuvant for delayed hypersensitivity in mice.

Snippe H and 2 others. Immunology, 1977. Cited by 52 papers, by iCite.

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ConductScience Library. Dimethyl diotadecyl ammonium bromide as adjuvant for delayed hypersensitivity in mice. Papers, record 591002. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/591002

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Dimethyl diotadecyl ammonium bromide as adjuvant for delayed hypersensitivity in mice.
PubMed
Journal
Immunology
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
52
iCite
Relative citation ratio, by iCite
1.67
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Snippe HH
2Belder MM
3Willers JMJ M

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adjuvants, ImmunologicMajor topic
Hypersensitivity, DelayedMajor topic
Quaternary Ammonium CompoundsMajor topic
Animals
Antigens
Cell Count
Cyclophosphamide
Female
Lymphoid Tissue
Mice
Time Factors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References10

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1787,426A semi-electronic device for measuring delayed hypersensitivity in the mouse by footpad swelling.J Immunol Methods1976https://conductscience.org/library/papers/787426PubMed
24,140,152In vitro stimulation of spleen cells of the mouse by DNP--carrier complexes.Immunology1974https://conductscience.org/library/papers/4140152PubMed
34,143,109The influence of epitope density on the immunological properties of hapten-protein conjugates. I. Characteristics of the immune response to hapten-coupled albumen with varying epitope density.Cell Immunol1974https://conductscience.org/library/papers/4143109PubMed
44,606,666Influence of cyclophosphamide on the delayed hypersensitivity of the mouse.Ann Immunol (Paris)1974https://conductscience.org/library/papers/4606666PubMed
54,586,738The role of Peyer's patch cells in antibody formation.Immunology1973https://conductscience.org/library/papers/4586738PubMed
648,502Delayed hypersensitivity in the mouse induced by hapten-carrier complexes.Immunology1975https://conductscience.org/library/papers/48502PubMed
74,539,832Selective induction of delayed hypersensitivity by a lipid conjugated protein antigen which is localized in thymus dependent lymphoid tissue.J Immunol1973https://conductscience.org/library/papers/4539832PubMed
84,815,095The role of lipid in the induction of hapten-specific delayed hypersensitivity and contact sensitivity.J Immunol1974https://conductscience.org/library/papers/4815095PubMed
94,997,585Immune response to chemically modified flagellin. I. Induction of antibody tolerance to flagellin by acetoacetylated derivatives of the protein.J Exp Med1971https://conductscience.org/library/papers/4997585PubMed
101,123,546Properties of conjugated protein immunogens which selectively stimulate delayed-type hypersensitivity.J Immunol1975https://conductscience.org/library/papers/1123546PubMed

Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMIDTitleJournalYearIn PapersSource
29,149,896Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines.J Nanobiotechnology2017https://conductscience.org/library/papers/29149896PubMed
19,152,701Silica-based cationic bilayers as immunoadjuvants.BMC Biotechnol2009https://conductscience.org/library/papers/19152701PubMed
17,302,734The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes.Immunology2007https://conductscience.org/library/papers/17302734PubMed
12,412,759Synergistic effects of locally administered cytostatic drugs and a surfactant on the development of delayed-type hypersensitivity to keyhole limpet haemocyanin in mice.Clin Exp Immunol1989https://conductscience.org/library/papers/12412759PubMed
8,432,607Murine peritoneal macrophages activated by the mycobacterial 65-kilodalton heat shock protein express enhanced microbicidal activity in vitro.Infect Immun1993https://conductscience.org/library/papers/8432607PubMed
7,910,595Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins.Infect Immun1994https://conductscience.org/library/papers/7910595PubMed
7,416,968Dimethyl dioctadecyl ammoniumbromide as an adjuvant for delayed type hypersensitivity and cellular immunity against Semliki Forest virus in mice.Arch Virol1980https://conductscience.org/library/papers/7416968PubMed
7,033,115Characterization of immunogenic properties of haptenated liposomal model membranes in mice. V. Effect of membrane composition on humoral and cellular immunogenicity.Immunology1981https://conductscience.org/library/papers/7033115PubMed
7,024,108Characterization of immunogenic properties of haptenated liposomal model membranes in mice. IV. induction of IgM memory.Immunology1981https://conductscience.org/library/papers/7024108PubMed
7,002,767Variable expression of delayed hypersensitivity in different mouse strains using dimethyl dioctadecyl ammonium bromide as an adjuvant.Immunology1980https://conductscience.org/library/papers/7002767PubMed

1 to 10 of 22

See all 22 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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