Paper5949593
Species variation in the amino acid sequence of insulin.
Smith LF. Am J Med, 1966. Cited by 325 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Species variation in the amino acid sequence of insulin. Papers, record 5949593. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/5949593
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics16
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Amino Acid Sequence | Major topic |
| Insulin | Major topic |
| Species Specificity | Major topic |
| Animals | |
| Cetacea | |
| Dogs | |
| Electrophoresis | |
| Elephants | |
| Humans | |
| In Vitro Techniques | |
| Male | |
| Poultry | |
| Rabbits | |
| Rats | |
| Spermatozoa | |
| Swine |
Source PubMed
Cited by45
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 325 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 36,002,588 | Derivatization with fatty acids in peptide and protein drug discovery. | Nat Rev Drug Discov | 2023 | https://conductscience.org/library/papers/36002588 | PubMed |
| 31,273,433 | Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species. | J Mol Evol | 2019 | https://conductscience.org/library/papers/31273433 | PubMed |
| 30,392,157 | The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content. | J Mol Evol | 2018 | https://conductscience.org/library/papers/30392157 | PubMed |
| 27,031,512 | Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. | PLoS One | 2016 | https://conductscience.org/library/papers/27031512 | PubMed |
| 25,946,091 | Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period. | PLoS One | 2015 | https://conductscience.org/library/papers/25946091 | PubMed |
| 24,843,567 | Zinc transporters and their role in the pancreatic β-cell. | J Diabetes Investig | 2012 | https://conductscience.org/library/papers/24843567 | PubMed |
| 24,765,678 | Relationship among insulin resistance, growth hormone, and insulin-like growth factor I concentrations in diestrous Swedish Elkhounds. | J Vet Intern Med | 2014 | https://conductscience.org/library/papers/24765678 | PubMed |
| 23,447,060 | Development of metabolic function biomarkers in the common marmoset, Callithrix jacchus. | Am J Primatol | 2013 | https://conductscience.org/library/papers/23447060 | PubMed |
| 19,706,465 | Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice. | Proc Natl Acad Sci U S A | 2009 | https://conductscience.org/library/papers/19706465 | PubMed |
| 19,186,147 | Interaction of IAPP and insulin with model interfaces studied using neutron reflectometry. | Biophys J | 2009 | https://conductscience.org/library/papers/19186147 | PubMed |
| 17,423,172 | Insulin treatment and development of anti-insulin antibodies in a horse with diabetes mellitus associated with a functional pituitary adenoma. | Can Vet J | 1988 | https://conductscience.org/library/papers/17423172 | PubMed |
| 8,251,071 | The effect of placement of tryptophan residues in selected A-chain positions on the biological profile of insulin. | J Protein Chem | 1993 | https://conductscience.org/library/papers/8251071 | PubMed |
| 8,002,937 | Characterization of insulins and proglucagon-derived peptides from a phylogenetically ancient fish, the paddlefish (Polyodon spathula). | Biochem J | 1994 | https://conductscience.org/library/papers/8002937 | PubMed |
| 7,045,871 | Biosynthesis of rat insulins I and II: evidence for differential expression of the two genes. | Proc Natl Acad Sci U S A | 1982 | https://conductscience.org/library/papers/7045871 | PubMed |
| 6,591,179 | Guinea pig preproinsulin gene: an evolutionary compromise? | Proc Natl Acad Sci U S A | 1984 | https://conductscience.org/library/papers/6591179 | PubMed |
| 6,281,170 | Assigning the polymorphic human insulin gene to the short arm of chromosome 11 by chromosome sorting. | Hum Genet | 1982 | https://conductscience.org/library/papers/6281170 | PubMed |
| 5,738,348 | The case for an "abnormal" insulin in diabetes mellitus. | Diabetologia | 1968 | https://conductscience.org/library/papers/5738348 | PubMed |
| 5,620,812 | Comparative aspects of the immunology and biology of insulin. | Diabetologia | 1967 | https://conductscience.org/library/papers/5620812 | PubMed |
| 5,494,803 | [Evidence for an abnormal insuli in diabetes mellitus]. | Acta Diabetol Lat | 1970 | https://conductscience.org/library/papers/5494803 | PubMed |
| 5,047,262 | Partial pancreatectomy and the role of insulin in carbohydrate metabolism in Gallus domesticus. | Diabetologia | 1972 | https://conductscience.org/library/papers/5047262 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| INS | 3,630 | PubTator's text mining | https://conductscience.org/library/genes/3630 |
Source NCBI Gene
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- References
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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