ConductScience.org, home

Paper60762

Determinants of antigenic molecules responsible for genetically controlled regulation of immune responses.

Schwartz M and 5 others. Proc Natl Acad Sci U S A, 1976. Cited by 47 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Determinants of antigenic molecules responsible for genetically controlled regulation of immune responses. Papers, record 60762. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/60762

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Determinants of antigenic molecules responsible for genetically controlled regulation of immune responses.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
47
iCite
Relative citation ratio, by iCite
0.89
iCite
Revised in PubMed
2021-12-03
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Schwartz MM
2Waltenbaugh CC
3Dorf MM
4Cesla RR
5Sela MM
6Benacerraf BB

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
GenesMajor topic
Histocompatibility AntigensMajor topic
PeptidesMajor topic
Alanine
Animals
Epitopes
Genetic Linkage
Glutamates
Immunosuppression Therapy
Mice
Mice, Inbred Strains
T-Lymphocytes
Tyrosine

Source PubMed

References21

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,059,157Complementation of H-2-linked Ir genes in the mouse.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1059157PubMed
21,079,849The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.J Exp Med1975https://conductscience.org/library/papers/1079849PubMed
31,194,855Genetic control of specific immune suppression. II. H-2-linked dominant genetic control of immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT).J Exp Med1975https://conductscience.org/library/papers/1194855PubMed
41,254,952Genetic control of immune response against random copolymers of glutamic acid and alanine (GA) and tyrosine (GT) in inbred mice.J Immunol1976https://conductscience.org/library/papers/1254952PubMed
64,109,878Histocompatibility-linked immune response genes.Science1972https://conductscience.org/library/papers/4109878PubMed
74,118,772Antibody response in rats to the synthetic polypeptide (T,G)-A--L genetically linked to the major histocompatibility system.Eur J Immunol1972https://conductscience.org/library/papers/4118772PubMed
84,126,766
Genetic control of immune responses in vitro. I. Development of primary and secondary plaque-forming cell responses to the random terpolymer 1-glutamic acid 60-1-alanine30-1-tyrosine10 (GAT) by mouse spleen cells in vitro.
J Exp Med1973https://conductscience.org/library/papers/4126766PubMed
94,136,183
Antibody response of inbred mouse strains to ordered tetrapeptides of tyrosine and glutamic acid attached to multichain polyalanine or polyproline. Tyr-Tyr-Glu-Glu is a major determinant of the random poly-(Tyr, Glu)-polyDLAla--polyLys.
J Exp Med1974https://conductscience.org/library/papers/4136183PubMed
104,137,682Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).J Exp Med1974https://conductscience.org/library/papers/4137682PubMed
114,208,749Histocompatibility-linked immune-response genes in the rhesus monkey.Transplant Proc1974https://conductscience.org/library/papers/4208749PubMed
124,542,806Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes.J Exp Med1973https://conductscience.org/library/papers/4542806PubMed
1346,593Ir-gene control of immunogenicity of insulin and A-chain loop as a carrier determinant.Nature1975https://conductscience.org/library/papers/46593PubMed
144,857,865Genetic control of immune responses in vitro. 3. Tolerogenic properties of the terpolymer L-glutamic acid 60-L-alanine30-L-tyrosine10 (GAT) for spleen cells from nonresponder (H-2s and H-2q) mice.J Exp Med1974https://conductscience.org/library/papers/4857865PubMed
154,934,502Immune responses in vitro. 3. Development of primary gamma-M, gamma-G, and gamma-A plaque-forming cell responses in mouse spleen cell cultures stimulated with heterologous erythrocytes.J Exp Med1971https://conductscience.org/library/papers/4934502PubMed
1652,219The stimulation of specific suppressor T cells in genetic non-responder mice by linear random copolymers of L-amino acids.Transplant Rev1975https://conductscience.org/library/papers/52219PubMed
175,271,167Linkage between the poly-L-lysine gene and the locus controlling the major histocompatibility antigens in strain 2 guinea pigs.Proc Natl Acad Sci U S A1970https://conductscience.org/library/papers/5271167PubMed
185,332,821Immunological studies with synthetic polypeptides.Adv Immunol1966https://conductscience.org/library/papers/5332821PubMed
1955,062The histocompatibility-linked immune response genes.Adv Cancer Res1975https://conductscience.org/library/papers/55062PubMed
2058,463Specificity of virus-immune effector T cells for H-2K or H-2D compatible interactions: implications for H-antigen diversity.Transplant Rev1976https://conductscience.org/library/papers/58463PubMed
215,938,816The behavior of hapten-poly-L-lysine conjugates as complete antigens in genetic responder and as haptens in nonresponder guinea pigs.J Exp Med1966https://conductscience.org/library/papers/5938816PubMed

See all 21 references

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 47 citations.

PMIDTitleJournalYearIn PapersSource
9,256,473A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens.Proc Natl Acad Sci U S A1997https://conductscience.org/library/papers/9256473PubMed
6,233,223Mechanisms of genetic control of immune responses. I. Evidence for distinct multi-step helper T-cell pathways in cellular and humoral responses to GAT.Immunogenetics1984https://conductscience.org/library/papers/6233223PubMed
6,196,105Coexistence of immunogenic and suppressogenic epitopes in tumor cells and various types of macromolecules.Cancer Immunol Immunother1983https://conductscience.org/library/papers/6196105PubMed
6,189,950T cell regulation of B cell activation. I-A-restricted T suppressor cells inhibit the major histocompatibility complex-restricted interactions of T helper cells with B cells and accessory cells.J Exp Med1983https://conductscience.org/library/papers/6189950PubMed
6,168,023Epitope-specific and idiotype-specific cellular interactions in a model protein antigen system.Springer Semin Immunopathol1980https://conductscience.org/library/papers/6168023PubMed
2,467,772Immune suppression genes.Clin Exp Immunol1989https://conductscience.org/library/papers/2467772PubMed
2,409,208Repertoires of T cells directed against a large protein antigen, beta-galactosidase. II. Only certain T helper or T suppressor cells are relevant in particular regulatory interactions.J Exp Med1985https://conductscience.org/library/papers/2409208PubMed
405,669Radioimmunoassay of a human serum growth factor for Balb/c-3T3 cells: derivation from platelets.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/405669PubMed
323,407Restriction of primary responses to the IgG class and dependency of IgM responses on secondary immunization for the copolymers of L-glutamic acid, L-tyrosine, and L-alanine.J Exp Med1977https://conductscience.org/library/papers/323407PubMed
301,177Histocompatibility linked immune responsiveness and restrictions imposed on sensitized lymphocytes.J Exp Med1977https://conductscience.org/library/papers/301177PubMed
88,500Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain.J Exp Med1979https://conductscience.org/library/papers/88500PubMed
71,736Key antigenic determinants in regulation of the immune response.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/71736PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/60762

GET https://conductscience.org/api/papers/v1/60762/references?page=2