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Paper · 6089101

The effect of Tityus serrulatus scorpion toxin gamma on Na channels in neuroblastoma cells.

Vijverberg HP and 2 others. Pflugers Arch, 1984. Cited by 57 papers, by iCite.

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ConductScience Library. The effect of Tityus serrulatus scorpion toxin gamma on Na channels in neuroblastoma cells. Papers, record 6089101. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6089101

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The effect of Tityus serrulatus scorpion toxin gamma on Na channels in neuroblastoma cells.
PubMed
Journal
Pflugers Arch
PubMed
Year
1984
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
57
iCite
Relative citation ratio, by iCite
1.8
iCite
Revised in PubMed
2019-07-26
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Vijverberg HPH P
2Pauron DD
3Lazdunski MM

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Ion ChannelsMajor topic
NeuroblastomaMajor topic
Scorpion VenomsMajor topic
SodiumMajor topic
Anesthetics, Local
Cell Line
Cell Membrane
Cells, Cultured
Humans
Membrane Potentials
Tetrodotoxin

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,147,916Scorpion neurotoxin - a presynaptic toxin which affects both Na+ and K+ channels in axons.Biochem Biophys Res Commun1975https://conductscience.org/library/papers/1147916PubMed
26,306,553Classification of Na channel receptors specific for various scorpion toxins.Pflugers Arch1983https://conductscience.org/library/papers/6306553PubMed
36,271,214Fluctuation analysis of Na+ channels modified by batrachotoxin in myelinated nerve.Biochim Biophys Acta1981https://conductscience.org/library/papers/6271214PubMed
4671,297Ionic currents in cultured mouse neuroblastoma cells under voltage-clamp conditions.J Physiol1978https://conductscience.org/library/papers/671297PubMed
56,315,420Electrophysiological characterization, solubilization and purification of the Tityus gamma toxin receptor associated with the gating component of the Na+ channel from rat brain.EMBO J1983https://conductscience.org/library/papers/6315420PubMed
66,281,796Batrachotoxin modifies the gating kinetics of sodium channels in internally perfused neuroblastoma cells.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6281796PubMed
76,306,554A quantitative study of the action of Centruroides sculpturatus toxins III and IV on the Na currents of the node of Ranvier.Pflugers Arch1983https://conductscience.org/library/papers/6306554PubMed
86,857,710Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus.Toxicon1983https://conductscience.org/library/papers/6857710PubMed
9660,159Properties of internally perfused, voltage-clamped, isolated nerve cell bodies.J Gen Physiol1978https://conductscience.org/library/papers/660159PubMed
106,162,910Some kinetic and steady-state properties of sodium channels after removal of inactivation.J Gen Physiol1981https://conductscience.org/library/papers/6162910PubMed

Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 57 citations.

PMIDTitleJournalYearIn PapersSource
20,300,540Scorpion venom and the inflammatory response.Mediators Inflamm2010https://conductscience.org/library/papers/20300540PubMed
17,698,594beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel.J Gen Physiol2007https://conductscience.org/library/papers/17698594PubMed
16,679,310Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.J Biol Chem2006https://conductscience.org/library/papers/16679310PubMed
15,678,093Selective release of ATP from sympathetic nerves of rat vas deferens by the toxin TsTX-I from Brazilian scorpion Tityus serrulatus.Br J Pharmacol2005https://conductscience.org/library/papers/15678093PubMed
15,672,678Dopamine release evoked by beta scorpion toxin, tityus gamma, in prefrontal cortical slices is mediated by intracellular calcium stores.Cell Mol Neurobiol2004https://conductscience.org/library/papers/15672678PubMed
14,570,407Sodium channel toxins and neurotransmitter release.Neurochem Res2003https://conductscience.org/library/papers/14570407PubMed
12,879,866Lucifer Yellow slows voltage-gated Na+ current inactivation in a light-dependent manner in mice.J Physiol2003https://conductscience.org/library/papers/12879866PubMed
12,585,699Modulation of Na+-channels by neurotoxins produces different effects on [3H]ACh release with mobilization of distinct Ca2+-channels.Cell Mol Neurobiol2002https://conductscience.org/library/papers/12585699PubMed
12,040,042Domain 2 of Drosophila para voltage-gated sodium channel confers insect properties to a rat brain channel.J Neurosci2002https://conductscience.org/library/papers/12040042PubMed
11,524,459Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin.J Gen Physiol2001https://conductscience.org/library/papers/11524459PubMed

1 to 10 of 17

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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