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Paper · 6301596

Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum in vivo.

Beubler E and 1 other. Br J Pharmacol, 1980. Cited by 57 papers, by iCite.

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ConductScience Library. Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum in vivo. Papers, record 6301596. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6301596

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum in vivo.
PubMed
Journal
Br J Pharmacol
PubMed
Year
1980
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
57
iCite
Relative citation ratio, by iCite
2.71
iCite
Revised in PubMed
2019-05-11
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Beubler EE
2Lembeck FF

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cyclic AMPMajor topic
Intestinal SecretionsMajor topic
MorphineMajor topic
Prostaglandins EMajor topic
Alprostadil
Animals
Antidiarrheals
Body Water
Female
Jejunum
Naloxone
Rats
Rats, Inbred Strains
Theophylline

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,371,639Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.Prostaglandins1974https://conductscience.org/library/papers/4371639PubMed
24,369,434Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa.J Clin Invest1974https://conductscience.org/library/papers/4369434PubMed
34,479,776Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 2: in vivo parenteral pharmacology and acute toxicity in mice. Comparison with morphine, codeine and diphenoxylate.Arzneimittelforschung1974https://conductscience.org/library/papers/4479776PubMed
44,374,095Theophylline, cyclic AMP, choleragen, and electrolyte transport by rabbit ileum.Am J Physiol1974https://conductscience.org/library/papers/4374095PubMed
54,374,398Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.FEBS Lett1974https://conductscience.org/library/papers/4374398PubMed
6163,008Morphine antagonises action of prostaglandin in neuroblastoma and neuroblastoma times glioma hybrid cells.Nature1975https://conductscience.org/library/papers/163008PubMed
71,054,841Morphine receptors as regulators of adenylate cyclase activity.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1054841PubMed
8170,157Effect of dioctyl sodium sulfosuccinate on colonic fluid and electrolyte movement.Gastroenterology1975https://conductscience.org/library/papers/170157PubMed
953,429Treatment of radiation-induced gastrointestinal distress with acetylsalicylate.Lancet1975https://conductscience.org/library/papers/53429PubMed
10934,356Methylxanthines and intestinal drug absorption.Naunyn Schmiedebergs Arch Pharmacol1976https://conductscience.org/library/papers/934356PubMed

1 to 10 of 33

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Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 57 citations.

PMIDTitleJournalYearIn PapersSource
41,385,024Mechanistic insights into opioid-induced pulmonary edema: receptor specificity and sodium transport.Ir J Med Sci2026https://conductscience.org/library/papers/41385024PubMed
7,712,008Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum in vivo.Br J Pharmacol1995https://conductscience.org/library/papers/7712008PubMed
6,890,394The effect of chlorpromazine on the function of colonic and ileal mucosa in the anaesthetized rat.Br J Pharmacol1982https://conductscience.org/library/papers/6890394PubMed
6,825,546Effects of bombesin, calcitonin, and enkephalin on canine jejunal water and electrolyte transport.Dig Dis Sci1983https://conductscience.org/library/papers/6825546PubMed
6,770,274Naloxone increases carbon dioxide stimulated respiration in the rabbit.Naunyn Schmiedebergs Arch Pharmacol1980https://conductscience.org/library/papers/6770274PubMed
6,272,133Loperamide reduces the intestinal secretion but not the mucosal cAMP accumulation induced by choleratoxin.Naunyn Schmiedebergs Arch Pharmacol1981https://conductscience.org/library/papers/6272133PubMed
6,271,319The action of loperamide in inhibiting prostaglandin-induced intestinal secretion in the rat.Br J Pharmacol1981https://conductscience.org/library/papers/6271319PubMed
6,253,842Influence of vasoactive intestinal polypeptide on net water flux and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum.Naunyn Schmiedebergs Arch Pharmacol1980https://conductscience.org/library/papers/6253842PubMed
6,140,061Characterization of the opiate receptor population mediating inhibition of VIP-induced secretion from the small intestine of the rat.Br J Pharmacol1983https://conductscience.org/library/papers/6140061PubMed
6,121,295Alpha 2-adrenoceptors inhibit the cholera-toxin-induced intestinal fluid accumulation.Naunyn Schmiedebergs Arch Pharmacol1982https://conductscience.org/library/papers/6121295PubMed

1 to 10 of 18

See all 18 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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