Paper64914
Human alpha2-macroglobulin.
Harpel PC. Methods Enzymol, 1976. Cited by 66 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Human alpha2-macroglobulin. Papers, record 64914. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/64914
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics13
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| alpha-Macroglobulins | Major topic |
| Amino Acids | |
| Chromatography, DEAE-Cellulose | |
| Chromatography, Gel | |
| Drug Stability | |
| Fibrinolysin | |
| Humans | |
| Macromolecular Substances | |
| Methods | |
| Molecular Weight | |
| Polyethylene Glycols | |
| Protein Binding | |
| Trypsin |
Source PubMed
Cited by29
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 66 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,964,382 | Human α2-Macroglobulin: Architecture, Mechanisms, and Functional Implications. | FASEB J | 2026 | https://conductscience.org/library/papers/41964382 | PubMed |
| 41,828,701 | Intracellular Signaling Regulated by Activated α2-Macroglobulin: Expanding Beyond Its Protease Inhibitory Role. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/41828701 | PubMed |
| 25,400,428 | Alpha-2-macroglobulin as a radioprotective agent: a review. | Chin J Cancer Res | 2014 | https://conductscience.org/library/papers/25400428 | PubMed |
| 22,896,034 | Acute phase proteins are major clients for the chaperone action of α₂-macroglobulin in human plasma. | Cell Stress Chaperones | 2013 | https://conductscience.org/library/papers/22896034 | PubMed |
| 21,683,247 | Serpin-Enzyme Receptors LDL Receptor-Related Protein 1. | Methods Enzymol | 2011 | https://conductscience.org/library/papers/21683247 | PubMed |
| 12,739,901 | Molecular cloning and structural characterization of the hagfish proteinase inhibitor of the alpha-2-macroglobulin family. | J Protein Chem | 2003 | https://conductscience.org/library/papers/12739901 | PubMed |
| 9,385,634 | Oxidation of apolipoprotein(a) inhibits kringle-associated lysine binding: the loss of intrinsic protein fluorescence suggests a role for tryptophan residues in the lysine binding site. | Protein Sci | 1997 | https://conductscience.org/library/papers/9385634 | PubMed |
| 8,246,183 | Neural differentiation in cleavage-arrested ascidian blastomeres induced by a proteolytic enzyme. | J Physiol | 1993 | https://conductscience.org/library/papers/8246183 | PubMed |
| 7,542,633 | Binding of native alpha 2-macroglobulin to human group G streptococci. | Infect Immun | 1995 | https://conductscience.org/library/papers/7542633 | PubMed |
| 7,515,888 | In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella. | J Cell Biol | 1994 | https://conductscience.org/library/papers/7515888 | PubMed |
| 6,448,870 | Natural inhibitors of fibrinolysis. | J Clin Pathol Suppl (R Coll Pathol) | 1980 | https://conductscience.org/library/papers/6448870 | PubMed |
| 6,199,019 | Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin. | Biochem J | 1984 | https://conductscience.org/library/papers/6199019 | PubMed |
| 6,198,647 | Specific covalent binding of platelet-derived growth factor to human plasma alpha 2-macroglobulin. | Proc Natl Acad Sci U S A | 1984 | https://conductscience.org/library/papers/6198647 | PubMed |
| 6,186,243 | Evidence for similar conformational changes in alpha 2-macroglobulin on reaction with primary amines or proteolytic enzymes. | Biochem J | 1982 | https://conductscience.org/library/papers/6186243 | PubMed |
| 6,174,421 | Polyclonal B-cell activator with esterolytic activity and polyclonal gammopathy induced by allogeneic cells in rabbits. | Immunology | 1982 | https://conductscience.org/library/papers/6174421 | PubMed |
| 6,166,634 | Alpha2-plasmin inhibitor and alpha2-macroglobulin-plasmin complexes in plasma. Quantitation by an enzyme-linked differential antibody immunosorbent assay. | J Clin Invest | 1981 | https://conductscience.org/library/papers/6166634 | PubMed |
| 6,100,805 | Proteolytic and metastatic activities of clones derived from a methylcholanthrene-induced murine fibrosarcoma. | Clin Exp Metastasis | 1983 | https://conductscience.org/library/papers/6100805 | PubMed |
| 3,487,555 | Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiency. | J Clin Invest | 1986 | https://conductscience.org/library/papers/3487555 | PubMed |
| 2,449,170 | Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond. | Biochem J | 1987 | https://conductscience.org/library/papers/2449170 | PubMed |
| 2,448,970 | Antigenic properties of human and animal bloodstains studied by enzyme-linked immunosorbent assay (ELISA) using various antisera against specific plasma proteins. | Z Rechtsmed | 1987 | https://conductscience.org/library/papers/2448970 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| A2M | 2 | PubTator's text mining | https://conductscience.org/library/genes/2 |
Source NCBI Gene
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- References
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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