Paper6602020
Synthesis of alpha 1-anti-trypsin by human monocytes.
van Furth R and 2 others. Clin Exp Immunol, 1983. Cited by 48 papers, by iCite.
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ConductScience Library. Synthesis of alpha 1-anti-trypsin by human monocytes. Papers, record 6602020. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6602020
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics10
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Monocytes | Major topic |
| alpha 1-Antitrypsin | Major topic |
| Cell Line | |
| Cells, Cultured | |
| Humans | |
| Immunoelectrophoresis | |
| Leukemia | |
| Liver | |
| Lymphocytes | |
| Phenotype |
Source PubMed
References22
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,161,984 | The formation of immunoglobulins by human tissues in vitro. I. The methods and their specificity. | Immunology | 1966 | https://conductscience.org/library/papers/4161984 | PubMed |
| 2 | 6,792,245 | Alpha-1-antitrypsin in human macrophages. | J Clin Pathol | 1981 | https://conductscience.org/library/papers/6792245 | PubMed |
| 3 | 4,179,068 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | Scand J Clin Lab Invest Suppl | 1968 | https://conductscience.org/library/papers/4179068 | PubMed |
| 4 | 4,182,334 | Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder. | J Lab Clin Med | 1969 | https://conductscience.org/library/papers/4182334 | PubMed |
| 5 | 4,201,266 | Interrelationships between the human alveolar macrophage and alpha-1-antitrypsin. | J Clin Invest | 1973 | https://conductscience.org/library/papers/4201266 | PubMed |
| 6 | 1,093,971 | In vitro synthesis of lysozyme by human and mouse tissues and leucocytes. | Immunology | 1975 | https://conductscience.org/library/papers/1093971 | PubMed |
| 7 | 178,611 | Establishment and characterization of a human histiocytic lymphoma cell line (U-937). | Int J Cancer | 1976 | https://conductscience.org/library/papers/178611 | PubMed |
| 8 | 300,300 | Application of isoelectric focusing in alpha1-antitrypsin phenotyping. | Clin Chim Acta | 1977 | https://conductscience.org/library/papers/300300 | PubMed |
| 9 | 191,472 | Alpha-1-antitrypsin bodies in the liver. | J Clin Pathol | 1977 | https://conductscience.org/library/papers/191472 | PubMed |
| 10 | 670,884 | The origin, kinetics, and characteristics of the Kupffer cells in the normal steady state. | J Exp Med | 1978 | https://conductscience.org/library/papers/670884 | PubMed |
| 11 | 360,063 | alpha1-antitrypsin deficiency (first of two parts). | N Engl J Med | 1978 | https://conductscience.org/library/papers/360063 | PubMed |
| 12 | 751,843 | Peroxidase cytochemistry and ultrastructure of resident macrophages in fetal rat liver. A developmental study. | Dev Biol | 1978 | https://conductscience.org/library/papers/751843 | PubMed |
| 13 | 448,291 | Origin, Kinetics, and characteristics of pulmonary macrophages in the normal steady state. | J Exp Med | 1979 | https://conductscience.org/library/papers/448291 | PubMed |
| 14 | 288,488 | Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. | Blood | 1979 | https://conductscience.org/library/papers/288488 | PubMed |
| 15 | 313,895 | Morphological identification of alpha-1-antitrypsin in pulmonary macrophages. | Hum Pathol | 1979 | https://conductscience.org/library/papers/313895 | PubMed |
| 16 | 91,062 | Alpha 1-antitrypsin in human macrophages. | Lancet | 1979 | https://conductscience.org/library/papers/91062 | PubMed |
| 17 | 6,990,422 | Determination of subpopulations of leukocytes involved in the synthesis of alpha 1-antitrypsin in vitro. | Proc Soc Exp Biol Med | 1980 | https://conductscience.org/library/papers/6990422 | PubMed |
| 18 | 6,769,626 | Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, alpha 1-antitrypsin, C8, and factor B. | Clin Immunol Immunopathol | 1980 | https://conductscience.org/library/papers/6769626 | PubMed |
| 19 | 6,967,489 | Danazol-induced augmentation of serum alpha 1-antitrypsin levels in individuals with marked deficiency of this antiprotease. | J Clin Invest | 1980 | https://conductscience.org/library/papers/6967489 | PubMed |
| 20 | 7,012,811 | Presence of alpha1-antichymotrypsin and alpha1-antitrypsin in haematopoietic and lymphoid tissue cells as revealed by the immunoperoxidase method. | Pathol Res Pract | 1980 | https://conductscience.org/library/papers/7012811 | PubMed |
Cited by13
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 36,009,277 | The Effect of Paracrine Factors Released by Irradiated Peripheral Blood Mononuclear Cells on Neutrophil Extracellular Trap Formation. | Antioxidants (Basel) | 2022 | https://conductscience.org/library/papers/36009277 | PubMed |
| 33,554,955 | Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice. | JCI Insight | 2021 | https://conductscience.org/library/papers/33554955 | PubMed |
| 26,555,091 | Human plasma protein N-glycosylation. | Glycoconj J | 2016 | https://conductscience.org/library/papers/26555091 | PubMed |
| 3,901,368 | Proteinases in inflammatory demyelinating disease. | Springer Semin Immunopathol | 1985 | https://conductscience.org/library/papers/3901368 | PubMed |
| 3,876,562 | The cellular defect in alpha 1-proteinase inhibitor (alpha 1-PI) deficiency is expressed in human monocytes and in Xenopus oocytes injected with human liver mRNA. | Proc Natl Acad Sci U S A | 1985 | https://conductscience.org/library/papers/3876562 | PubMed |
| 3,871,944 | Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages. | Proc Natl Acad Sci U S A | 1985 | https://conductscience.org/library/papers/3871944 | PubMed |
| 3,685,250 | Accumulation of anthracotic particles along lymphatics of the human lung: relevance to "hot spot" formation after inhalation of poorly soluble radionuclides. | Radiat Environ Biophys | 1987 | https://conductscience.org/library/papers/3685250 | PubMed |
| 3,552,338 | Change in alpha 1-antitrypsin phenotype after orthotopic liver transplant. | Clin Exp Immunol | 1986 | https://conductscience.org/library/papers/3552338 | PubMed |
| 3,488,959 | Human lymphocytes synthesize C-reactive protein. | Inflammation | 1986 | https://conductscience.org/library/papers/3488959 | PubMed |
| 3,259,253 | The inhibitory complex of human alpha 1-proteinase inhibitor and human leukocyte elastase is a neutrophil chemoattractant. | J Exp Med | 1988 | https://conductscience.org/library/papers/3259253 | PubMed |
| 2,433,944 | Inflammatory mediators and modulators released in organ culture from rabbit skin lesions produced in vivo by sulfur mustard. III. Electrophoretic protein fractions, trypsin-inhibitory capacity, alpha 1-proteinase inhibitor, and alpha 1- and alpha 2-macroglobulin proteinase inhibitors of culture fluids and serum. | Am J Pathol | 1987 | https://conductscience.org/library/papers/2433944 | PubMed |
| 2,160,188 | Modulation of macrophage protease activity by acute administration of O,O,S trimethyl phosphorothioate. | Agents Actions | 1990 | https://conductscience.org/library/papers/2160188 | PubMed |
| 1,318,806 | Alpha-1 anti-trypsin and CD30 expression occur in parallel in activated T cells. | Clin Exp Immunol | 1992 | https://conductscience.org/library/papers/1318806 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| SERPINA1 | 5,265 | PubTator's text mining | https://conductscience.org/library/genes/5265 |
Source NCBI Gene
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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