Paper · 6602202

Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells.

Clayberger C and 3 others. J Exp Med, 1983. Cited by 73 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells. Papers, record 6602202. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6602202

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells.; PubMed
Journal: J Exp Med; PubMed
Year: 1983; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6602202/; PubMed
DOI: https://doi.org/10.1084/jem.157.6.1906; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2187041/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 73; iCite
Relative citation ratio, by iCite: 1.27; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Clayberger C	C
2	Dekruyff RH	R H
3	Aisenberg J	J
4	Cantor H	H

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Haptens	Major topic
T-Lymphocytes	Major topic
Animals
Clone Cells
Histocompatibility Antigens Class II
Lymphocyte Activation
Major Histocompatibility Complex
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred C57BL
Nitrophenols
Phenylacetates
Trinitrobenzenes

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
AI12184	NIAID NIH HHS	United States	R01AI012184	PubMed and NIH	NIH RePORTER
AI13600	NIAID NIH HHS	United States	R01AI013600	PubMed and NIH	NIH RePORTER
CA26695	NCI NIH HHS	United States	R01CA026695	PubMed and NIH	NIH RePORTER
			R37AI012184	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	7,026,263	Antibody feedback regulation in vitro: T helper cell activation and T-B cell cooperation are not impaired by anti-carrier antibody.	Eur J Immunol	1981	https://conductscience.org/library/papers/7026263	PubMed
2	87,434	Lipid-modified antigens. I. Specificity of guinea pig T lymphocyte responses and I-region restriction.	J Immunol	1979	https://conductscience.org/library/papers/87434	PubMed
3	6,458,554	Ia antigens as restriction molecules in Ir-gene controlled T-cell proliferation.	Immunol Rev	1981	https://conductscience.org/library/papers/6458554	PubMed
4	4,102,686	The functional dissection of an antigen molecule: specificity of humoral and cellular immune responses to glucagon.	J Exp Med	1971	https://conductscience.org/library/papers/4102686	PubMed
5	6,271,869	Parallel cross-reactivity patterns of 2 sets of antigenically distinct cytochrome c peptides: possible evidence for a presentational model of Ir gene function.	J Immunol	1981	https://conductscience.org/library/papers/6271869	PubMed
6	315,877	Cytotoxic T cell responses to haptenated cells. I. Primary, secondary and long-term cultures.	Eur J Immunol	1979	https://conductscience.org/library/papers/315877	PubMed
7	6,157,540	Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells.	Eur J Immunol	1980	https://conductscience.org/library/papers/6157540	PubMed
8	7,188,699	Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.	J Immunol	1980	https://conductscience.org/library/papers/7188699	PubMed
9	4,137,682	Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).	J Exp Med	1974	https://conductscience.org/library/papers/4137682	PubMed
10	63,531	The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes.	J Exp Med	1976	https://conductscience.org/library/papers/63531	PubMed

1 to 10 of 34

See all 34 references

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 73 citations.

PMID	Title	Journal	Year	In Papers	Source
15,493,260	The T-cell response to haptenated insulins. I. The proliferative response.	Immunology	1989	https://conductscience.org/library/papers/15493260	PubMed
10,841,571	Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D.	Proc Natl Acad Sci U S A	2000	https://conductscience.org/library/papers/10841571	PubMed
6,198,431	Activation specificity of arsonate-reactive T cell clones. Structural requirements for hapten recognition and comparison with monoclonal antibodies.	J Exp Med	1984	https://conductscience.org/library/papers/6198431	PubMed
6,196,433	Hapten reactive inducer T cells. II. Evidence that a secreted form of the T cell receptor induces antibody production.	J Exp Med	1983	https://conductscience.org/library/papers/6196433	PubMed
3,876,930	Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.	EMBO J	1985	https://conductscience.org/library/papers/3876930	PubMed
3,871,522	Identification of a unique B-cell-stimulating factor produced by a cloned dendritic cell.	Proc Natl Acad Sci U S A	1985	https://conductscience.org/library/papers/3871522	PubMed
3,864,163	Cloning of Ly-5 cDNA.	Proc Natl Acad Sci U S A	1985	https://conductscience.org/library/papers/3864163	PubMed
3,257,903	Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens.	Cancer Immunol Immunother	1988	https://conductscience.org/library/papers/3257903	PubMed
3,023,970	Immunologically distinct p53 molecules generated by alternative splicing.	Mol Cell Biol	1986	https://conductscience.org/library/papers/3023970	PubMed
2,965,815	rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.	Proc Natl Acad Sci U S A	1988	https://conductscience.org/library/papers/2965815	PubMed

1 to 10 of 16

See all 16 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/6602202

GET https://conductscience.org/api/papers/v1/6602202/references?page=2

API reference For AI assistants