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Paper · 63531

The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes.

Janeway CA and 1 other. J Exp Med, 1976. Cited by 25 papers, by iCite.

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ConductScience Library. The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes. Papers, record 63531. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/63531

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes.
PubMed
Journal
J Exp Med
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
25
iCite
Relative citation ratio, by iCite
0.43
iCite
Revised in PubMed
2019-05-08
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Janeway CAC A
2Paul WEW E

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DinitrobenzenesMajor topic
EpitopesMajor topic
NitrobenzenesMajor topic
T-LymphocytesMajor topic
Animals
Ascitic Fluid
Binding Sites
Bromodeoxyuridine
Carrier Proteins
Cell Survival
Cross Reactions
Guinea Pigs
Haptens
Immune Tolerance
Light
Lymphocyte Activation

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References19

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,097,352THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.Biochem J1963https://conductscience.org/library/papers/14097352PubMed
24,108,424Functional specificity of antigen-binding receptors of lymphocytes.Transplant Rev1970https://conductscience.org/library/papers/4108424PubMed
358,456The specificity of T lymphocyte responses to chemically defined antigens.Transplant Rev1976https://conductscience.org/library/papers/58456PubMed
46,027,783Synthetic antigens composed exclusively of L- or D-amino acids. I. Effect of optical configuration on the immunogenicity of synthetic polypeptides in mice.Immunology1967https://conductscience.org/library/papers/6027783PubMed
563,530The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation.J Exp Med1976https://conductscience.org/library/papers/63530PubMed
6802,471Comparison of specificities of humoral and cellular immune response to haptens.Eur J Immunol1975https://conductscience.org/library/papers/802471PubMed
74,130,110
Failure to induce tolerance to 2,4-dinitrochlorobenzene contact sensitivity with a 2,4-dinitrophenyl (DNP) conjugate of a copolymer of D-glutamic acid and D-lysine, a specific tolerogen for DNP B cells.
J Immunol1974https://conductscience.org/library/papers/4130110PubMed
84,395,780Hapten competition and the nature of cell-cooperation in the antibody response.Proc R Soc Lond B Biol Sci1971https://conductscience.org/library/papers/4395780PubMed
94,403,472Simultaneous suppression of responses to allogeneic tissue in vitro and in vivo.Cell Immunol1972https://conductscience.org/library/papers/4403472PubMed
104,539,833Hapten-specific tolerance: depressed humoral and normal cellular immune responses.J Immunol1973https://conductscience.org/library/papers/4539833PubMed

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 25 citations.

PMIDTitleJournalYearIn PapersSource
23,947,343Immunity to viruses.Immunol Rev2013https://conductscience.org/library/papers/23947343PubMed
6,602,202Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells.J Exp Med1983https://conductscience.org/library/papers/6602202PubMed
2,460,578MHC-restricted recognition of immunogenic T cell epitopes of pertussis toxin reveals determinants in man distinct from the ADP-ribosylase active site.J Exp Med1988https://conductscience.org/library/papers/2460578PubMed
306,404T cells specific for hapten-modified self are precommitted for self major histocompatibility complex antigens before encounter with the hapten.J Exp Med1978https://conductscience.org/library/papers/306404PubMed
233,906Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells.J Exp Med1977https://conductscience.org/library/papers/233906PubMed
84,044Lymphocyte specificity to protein antigens. II. Fine specificity of T-cell activation with cytochrome c and derived peptides as antigenic probes.J Exp Med1979https://conductscience.org/library/papers/84044PubMed
77,841Specificity of murine delayed-type hypersensitivity to conjugates of large or small haptens on protein carriers bearing lipid groups.Immunology1978https://conductscience.org/library/papers/77841PubMed
68,474Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/68474PubMed
63,530The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation.J Exp Med1976https://conductscience.org/library/papers/63530PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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