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Paper · 63530

The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation.

Janeway CA and 3 others. J Exp Med, 1976. Cited by 10 papers, by iCite.

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ConductScience Library. The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation. Papers, record 63530. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/63530

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation.
PubMed
Journal
J Exp Med
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
10
iCite
Relative citation ratio, by iCite
0.2
iCite
Revised in PubMed
2019-05-08
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Janeway CAC A
2Maurer PHP H
3Dailey MOM O
4Inman JKJ K

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
EpitopesMajor topic
Lymphocyte ActivationMajor topic
T-LymphocytesMajor topic
Animals
Binding Sites
Carrier Proteins
Dinitrobenzenes
Female
Guinea Pigs
Haptens
Male
Mycobacterium tuberculosis
Nitrohydroxyiodophenylacetate
Peptides
Species Specificity
Structure-Activity Relationship

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,078,834Cellular cooperation during in vivo anti-hapten antibody responses. I. The effect of cell number on the response.J Immunol1975https://conductscience.org/library/papers/1078834PubMed
21,083,069Immunoglobulin-receptors revisited.Science1975https://conductscience.org/library/papers/1083069PubMed
313,798,685Studies on hypersensitivity. III. The relation between delayed reactivity to the picryl group of conjugates and contact sensitivity.Immunology1959https://conductscience.org/library/papers/13798685PubMed
413,867,017Immunological specificity of delayed and immediate hypersensitivity reactions.J Exp Med1962https://conductscience.org/library/papers/13867017PubMed
514,176,288ANTIGENICITY OF POLYPEPTIDES (POLY ALPHA AMINO ACIDS). XII. IMMUNOLOGICAL STUDIES WITH A NEW GROUP OF SYNTHETIC COPOLYMERS.J Exp Med1964https://conductscience.org/library/papers/14176288PubMed
614,271,319ANTIGENICITY OF POLYPEPTIDES (POLY ALPHA AMINO ACIDS). 13. IMMUNOLOGICAL STUDIES WITH SYNTHETIC POLYMERS CONTAINING ONLY D- OR D- AND L-ALPHA-AMINO ACIDS.J Exp Med1965https://conductscience.org/library/papers/14271319PubMed
714,978,857The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation.Eur J Immunol1971https://conductscience.org/library/papers/14978857PubMed
84,108,424Functional specificity of antigen-binding receptors of lymphocytes.Transplant Rev1970https://conductscience.org/library/papers/4108424PubMed
94,161,471Determination of free amino groups in proteins by trinitrobenzenesulfonic acid.Anal Biochem1966https://conductscience.org/library/papers/4161471PubMed
104,395,780Hapten competition and the nature of cell-cooperation in the antibody response.Proc R Soc Lond B Biol Sci1971https://conductscience.org/library/papers/4395780PubMed

1 to 10 of 25

See all 25 references

Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMIDTitleJournalYearIn PapersSource
6,602,202Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells.J Exp Med1983https://conductscience.org/library/papers/6602202PubMed
6,161,200Antigen-specific helper T cells required for dominant production of an idiotype (THId) are not under immune response (Ir) gene control.J Exp Med1980https://conductscience.org/library/papers/6161200PubMed
77,841Specificity of murine delayed-type hypersensitivity to conjugates of large or small haptens on protein carriers bearing lipid groups.Immunology1978https://conductscience.org/library/papers/77841PubMed
70,501Specificity of cytotoxic effector cells directed against trinitrobenzene sulfonate-modified syngeneic cells. Failure to recognize cell surface-bound trinitrophenyl dextran.J Exp Med1977https://conductscience.org/library/papers/70501PubMed
63,531The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes.J Exp Med1976https://conductscience.org/library/papers/63531PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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