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Paper · 6767239

Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.

Gough NM and 4 others. Proc Natl Acad Sci U S A, 1980. Cited by 72 papers, by iCite.

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ConductScience Library. Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain. Papers, record 6767239. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6767239

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1980
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
72
iCite
Relative citation ratio, by iCite
1.45
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gough NMN M
2Kemp DJD J
3Tyler BMB M
4Adams JMJ M
5Cory SS

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
Immunoglobulin Constant RegionsMajor topic
Immunoglobulin Heavy ChainsMajor topic
Immunoglobulin mu-ChainsMajor topic
ImmunoglobulinsMajor topic
Myeloma ProteinsMajor topic
Animals
Codon
DNA, Recombinant
Mice
Plasmacytoma
Protein Conformation
RNA, Messenger
Recombination, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,160,200The molecular basis of antibody formation: a paradox.Proc Natl Acad Sci U S A1965https://conductscience.org/library/papers/4160200PubMed
214,129,718SINGLE CELL STUDIES ON 19S ANTIBODY PRODUCTION.J Exp Med1964https://conductscience.org/library/papers/14129718PubMed
34,611,173Biological activities of immunoglobulins of different classes and subclasses.Adv Immunol1974https://conductscience.org/library/papers/4611173PubMed
41,195,397Detection of specific sequences among DNA fragments separated by gel electrophoresis.J Mol Biol1975https://conductscience.org/library/papers/1195397PubMed
5781,674Hybridization of RNA to double-stranded DNA: formation of R-loops.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/781674PubMed
6787,937A simple method for DNA restriction site mapping.Nucleic Acids Res1976https://conductscience.org/library/papers/787937PubMed
7847,462Charon phages: safer derivatives of bacteriophage lambda for DNA cloning.Science1977https://conductscience.org/library/papers/847462PubMed
8322,279Screening lambdagt recombinant clones by hybridization to single plaques in situ.Science1977https://conductscience.org/library/papers/322279PubMed
9881,736Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.J Mol Biol1977https://conductscience.org/library/papers/881736PubMed
10409,716Immunoglobulin structure and genetics. Identity between variable regions of a mu and a gamma2 chain.J Biol Chem1977https://conductscience.org/library/papers/409716PubMed

1 to 10 of 34

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Cited by23

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 72 citations.

PMIDTitleJournalYearIn PapersSource
41,528,574Dynamic Changes in Serum Biochemical Indices and Alternative Splicing Events Revealed Molecular Regulatory Mechanisms in Rainbow Trout Under Copper Stress.Mar Biotechnol (NY)2026https://conductscience.org/library/papers/41528574PubMed
6,813,678Biosynthesis and structure of membrane and secretory immunoglobulins.Mol Cell Biochem1982https://conductscience.org/library/papers/6813678PubMed
6,789,141A general function of noncoding polynucleotide sequences. Mass binding of transconformational proteins.Mol Biol Rep1981https://conductscience.org/library/papers/6789141PubMed
6,787,604Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6787604PubMed
6,787,590Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6787590PubMed
6,784,123Transcripts of the immunoglobulin C mu gene vary in structure and splicing during lymphoid development.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6784123PubMed
6,780,980Organization of the sequences flanking immunoglobulin heavy chain genes and their role in class switching.Nucleic Acids Res1980https://conductscience.org/library/papers/6780980PubMed
6,779,282Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6779282PubMed
6,777,755Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA.Nucleic Acids Res1980https://conductscience.org/library/papers/6777755PubMed
6,776,532Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6776532PubMed

1 to 10 of 23

See all 23 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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