Paper · 6980191

Lipopolysaccharides from Bacteroides fragilis are mitogenic for spleen cells from endotoxin responder and nonresponder mice.

Joiner KA and 2 others. Infect Immun, 1982. Cited by 42 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Lipopolysaccharides from Bacteroides fragilis are mitogenic for spleen cells from endotoxin responder and nonresponder mice. Papers, record 6980191. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6980191

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Lipopolysaccharides from Bacteroides fragilis are mitogenic for spleen cells from endotoxin responder and nonresponder mice.; PubMed
Journal: Infect Immun; PubMed
Year: 1982; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6980191/; PubMed
DOI: https://doi.org/10.1128/iai.36.3.1139-1145.1982; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC551449/; PubMed
The journal: https://conductscience.org/library/journal-index/0246127; PubMed
Citations, by iCite: 42; iCite
Relative citation ratio, by iCite: 1.68; iCite
Revised in PubMed: 2021-05-26; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Joiner KA	K A
2	McAdam KP	K P
3	Kasper DL	D L

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Bacteroides fragilis	Major topic
Lipopolysaccharides	Major topic
Lymphocyte Activation	Major topic
Mitogens	Major topic
Cell Membrane
Endotoxins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,867,999	Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235.	Biochemistry	1967	https://conductscience.org/library/papers/4867999	PubMed
2	5,806,584	The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.	J Biol Chem	1969	https://conductscience.org/library/papers/5806584	PubMed
3	4,577,879	Mitogenicity of bacterial endotoxins: characterization of the mitogenic principle.	J Immunol	1973	https://conductscience.org/library/papers/4577879	PubMed
4	4,579,014	Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4579014	PubMed
5	804,483	Fractions of lipopolysaccharide from Escherichia coli O111:B4 prepared by two extraction procedures.	J Biol Chem	1975	https://conductscience.org/library/papers/804483	PubMed
6	1,095,497	Bacterial endotoxins. The second Carl Prausnitz Memorial Lecture.	Int Arch Allergy Appl Immunol	1975	https://conductscience.org/library/papers/1095497	PubMed
7	1,095,681	The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen.	J Exp Med	1975	https://conductscience.org/library/papers/1095681	PubMed
8	810,521	Immunochemical characterization of the outer membrane complex of Bacteroides fragilis subspecies fragilis.	J Infect Dis	1975	https://conductscience.org/library/papers/810521	PubMed
9	939,922	Chemical and biological characterization of the lipopolysaccharide of Bacteroides fragilis subspecies fragilis.	J Infect Dis	1976	https://conductscience.org/library/papers/939922	PubMed
10	784,892	Endotoxin protein: a B-cell mitogen and polyclonal activator of C3H/HeJ lymphocytes.	J Exp Med	1976	https://conductscience.org/library/papers/784892	PubMed

1 to 10 of 24

See all 24 references

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 42 citations.

PMID	Title	Journal	Year	In Papers	Source
29,134,546	Effect of hyperbaric air on endotoxin from Bacteroides fragilis strains.	Folia Microbiol (Praha)	2018	https://conductscience.org/library/papers/29134546	PubMed
16,113,279	Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4.	Infect Immun	2005	https://conductscience.org/library/papers/16113279	PubMed
10,085,012	Lipopolysaccharides (LPS) of oral black-pigmented bacteria induce tumor necrosis factor production by LPS-refractory C3H/HeJ macrophages in a way different from that of Salmonella LPS.	Infect Immun	1999	https://conductscience.org/library/papers/10085012	PubMed
9,353,030	A novel component different from endotoxin extracted from Prevotella intermedia ATCC 25611 activates lymphoid cells from C3H/HeJ mice and gingival fibroblasts from humans.	Infect Immun	1997	https://conductscience.org/library/papers/9353030	PubMed
8,841,520	Splenic B-cell activation in lipopolysaccharide-non-responsive C3H/HeJ mice by lipopolysaccharide of Porphyromonas gingivalis.	Experientia	1996	https://conductscience.org/library/papers/8841520	PubMed
7,721,702	Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis.	J Bacteriol	1995	https://conductscience.org/library/papers/7721702	PubMed
3,882,561	Biochemical and immunobiological properties of lipopolysaccharide (LPS) from Bacteroides gingivalis and comparison with LPS from Escherichia coli.	Infect Immun	1985	https://conductscience.org/library/papers/3882561	PubMed
3,384,476	Bacteroides vulgatus outer membrane antigens associated with carrageenan-induced colitis in guinea pigs.	Infect Immun	1988	https://conductscience.org/library/papers/3384476	PubMed
2,917,784	Comparison of the biological responses induced by lipopolysaccharide and endotoxin of Treponema hyodysenteriae and Treponema innocens.	Infect Immun	1989	https://conductscience.org/library/papers/2917784	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/6980191

GET https://conductscience.org/api/papers/v1/6980191/references?page=2

API reference For AI assistants