Paper70349

Metabolic instability of myelin proteins. Breakdown of basic protein induced by brain cathepsin D.

Benuck M and 2 others. Eur J Biochem, 1975. Cited by 64 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Metabolic instability of myelin proteins. Breakdown of basic protein induced by brain cathepsin D. Papers, record 70349. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/70349

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Metabolic instability of myelin proteins. Breakdown of basic protein induced by brain cathepsin D.; PubMed
Journal: Eur J Biochem; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/70349/; PubMed
DOI: https://doi.org/10.1111/j.1432-1033.1975.tb04033.x; PubMed
The journal: https://conductscience.org/library/journal-index/0107600; PubMed
Citations, by iCite: 64; iCite
Relative citation ratio, by iCite: 1.69; iCite
Revised in PubMed: 2019-06-20; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Benuck M	M
2	Marks N	N
3	Hashim GA	G A

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Brain	Major topic
Cathepsins	Major topic
Myelin Basic Protein	Major topic
Amino Acids
Animals
Cattle
Drug Stability
Peptide Fragments

Source PubMed

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Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 64 citations.

PMID	Title	Journal	Year	In Papers	Source
34,502,116	Tau Protein Interaction Partners and Their Roles in Alzheimer's Disease and Other Tauopathies.	Int J Mol Sci	2021	https://conductscience.org/library/papers/34502116	PubMed
24,272,051	The role of proteolytic enzymes in demyelination in experimental allergic encephalomyelitis.	Neurochem Res	1977	https://conductscience.org/library/papers/24272051	PubMed
24,271,248	The breakdown of myelin-bound proteins by intra- and extracellular proteases.	Neurochem Res	1976	https://conductscience.org/library/papers/24271248	PubMed
18,396,408	Cathepsin D--many functions of one aspartic protease.	Crit Rev Oncol Hematol	2008	https://conductscience.org/library/papers/18396408	PubMed
9,358,770	Mononuclear phagocyte hydrolytic enzyme activity associated with cerebral HIV-1 infection.	Am J Pathol	1997	https://conductscience.org/library/papers/9358770	PubMed
7,566,359	Myelin basic protein purified on an ion-exchange continuous polymer bed in the presence of ethylene glycol and salt possesses activity against p-nitrophenyl acetate.	Neurochem Res	1995	https://conductscience.org/library/papers/7566359	PubMed
6,178,399	The polyadenylated RNA directing the synthesis of the rat myelin basic proteins is present in both free and membrane-bound forebrain polyribosomes.	Biochem J	1982	https://conductscience.org/library/papers/6178399	PubMed
6,169,802	Myelin basic protein in cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases.	J Neurol	1981	https://conductscience.org/library/papers/6169802	PubMed
2,426,610	Isolation and characterization of cathepsin B from bovine brain.	Neurochem Res	1986	https://conductscience.org/library/papers/2426610	PubMed
1,281,293	Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC).	Neurochem Res	1992	https://conductscience.org/library/papers/1281293	PubMed
307,703	Treatment of experimental allergic encephalomyelitis with an inhibitor of cathepsin D (pepstatin).	Neurochem Res	1978	https://conductscience.org/library/papers/307703	PubMed
79,987	Myelin basic protein-stimulated rosette-forming T cells in multiple sclerosis.	Neurochem Res	1978	https://conductscience.org/library/papers/79987	PubMed

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
CTSD	1,509	PubTator's text mining	https://conductscience.org/library/genes/1509	NCBI Gene
MBP	4,155	PubTator's text mining	https://conductscience.org/library/genes/4155	NCBI Gene

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

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Data

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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