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Paper723972

New type of nerve-mediated cholinergic contractions of the guinea-pig small intestine and its selective blockade by capsaicin.

Szolcsányi J and 1 other. Naunyn Schmiedebergs Arch Pharmacol, 1978. Cited by 100 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. New type of nerve-mediated cholinergic contractions of the guinea-pig small intestine and its selective blockade by capsaicin. Papers, record 723972. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/723972

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
New type of nerve-mediated cholinergic contractions of the guinea-pig small intestine and its selective blockade by capsaicin.
PubMed
Journal
Naunyn Schmiedebergs Arch Pharmacol
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
100
iCite
Relative citation ratio, by iCite
4.25
iCite
Revised in PubMed
2019-07-25
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Szolcsányi JJ
2Barthó LL

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CapsaicinMajor topic
Fatty Acids, UnsaturatedMajor topic
IleumMajor topic
Muscle ContractionMajor topic
Muscle, SmoothMajor topic
Parasympathetic Nervous SystemMajor topic
Animals
Duodenum
Electric Stimulation
Female
Guinea Pigs
In Vitro Techniques
Male
Stomach
Vagotomy
Vagus Nerve

Source PubMed

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,884,063Effect of guanethidine in revealing cholinergic sympathetic fibres.Br J Pharmacol Chemother1961https://conductscience.org/library/papers/13884063PubMed
24,141,638Formation of a factor increasing vascular permeability during electrical stimulation of the saphenous nerve in rats.Br J Pharmacol1974https://conductscience.org/library/papers/4141638PubMed
36,055,248Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin.Br J Pharmacol Chemother1967https://conductscience.org/library/papers/6055248PubMed
51,243,658Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents.Arzneimittelforschung1975https://conductscience.org/library/papers/1243658PubMed
618,581Effects of sympathetic nerve stimulation on electrical activity of Auerbach's plexus and intestinal smooth muscle tone.J Pharm Pharmacol1977https://conductscience.org/library/papers/18581PubMed
74,381,374A periarterial nerve-circular muscle preparation from the caecum of the guinea-pig.J Pharm Pharmacol1966https://conductscience.org/library/papers/4381374PubMed
81,143,357Functional and fine structural characteristics of the sensory neuron blocking effect of capsaicin.Naunyn Schmiedebergs Arch Pharmacol1975https://conductscience.org/library/papers/1143357PubMed
913,705,341The inhibitory action of the sympathetic nerves on the smooth muscle of the rabbit gut, its reversal by reserpine and restoration by catechol amines and by DOPA.J Physiol1961https://conductscience.org/library/papers/13705341PubMed
10842,619Excitation conduction in Auerbach's plexus of rabbit small intestine.Am J Physiol1977https://conductscience.org/library/papers/842619PubMed
115,942,028The effect of some anticholinesterases on the response of the taenia to sympathetic nerve stimulation.J Physiol1966https://conductscience.org/library/papers/5942028PubMed
12926,026A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain.J Physiol (Paris)1977https://conductscience.org/library/papers/926026PubMed
1316,992,436Two types of neurones in the myenteric plexus of duodenum in the guinea-pig.J Physiol1974https://conductscience.org/library/papers/16992436PubMed
1419,108,166Origin of the cholinergic response of the rabbit intestine to stimulation of its extrinsic sympathetic nerves after exposure to sympathetic blocking agents.Br J Pharmacol Chemother1962https://conductscience.org/library/papers/19108166PubMed
184,298,238The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat.Br J Pharmacol Chemother1968https://conductscience.org/library/papers/4298238PubMed
195,679,796Effects of capsaicin upon the stimulatory action of potassium chloride in the visceral branches of spinal afferents of the cat.Acta Physiol Acad Sci Hung1968https://conductscience.org/library/papers/5679796PubMed
21991,938Mechanism of morphine block of electrical activity in ganglia of Auerbach's plexus.Eur J Pharmacol1976https://conductscience.org/library/papers/991938PubMed
2313,867,378Studies on sympathetic mechanisms in isolated intestinal and vas deferens preparations.Br J Pharmacol Chemother1962https://conductscience.org/library/papers/13867378PubMed
244,783,093Intracellular recording from the myenteric plexus of the guinea-pig ileum.J Physiol1973https://conductscience.org/library/papers/4783093PubMed
2631,571The site of action of capsaicin on the guinea-pig isolated ileum.Naunyn Schmiedebergs Arch Pharmacol1978https://conductscience.org/library/papers/31571PubMed
2714,081,661THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM.Br J Pharmacol Chemother1963https://conductscience.org/library/papers/14081661PubMed

See all 24 references

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 100 citations.

PMIDTitleJournalYearIn PapersSource
37,240,118The Vanilloid (Capsaicin) Receptor TRPV1 in Blood Pressure Regulation: A Novel Therapeutic Target in Hypertension?Int J Mol Sci2023https://conductscience.org/library/papers/37240118PubMed
7,812,624Inhibitory effects of capsaicin on acetylcholine-evoked responses in rat phaeochromocytoma cells.Br J Pharmacol1994https://conductscience.org/library/papers/7812624PubMed
6,189,543The influence of substance P on the response of guinea-pig isolated ileum to periarterial nerve stimulation.Br J Pharmacol1983https://conductscience.org/library/papers/6189543PubMed
6,185,670Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to release of substance P.J Physiol1982https://conductscience.org/library/papers/6185670PubMed
6,180,331Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to substance P release.Naunyn Schmiedebergs Arch Pharmacol1982https://conductscience.org/library/papers/6180331PubMed
3,951,565Capsaicin-sensitive afferent neurones and gastrointestinal propulsion in the rat.Naunyn Schmiedebergs Arch Pharmacol1986https://conductscience.org/library/papers/3951565PubMed
3,580,706Evaluation of a new and potent cholecystokinin antagonist on motor responses of the guinea-pig intestine.Br J Pharmacol1987https://conductscience.org/library/papers/3580706PubMed
3,491,329
Extrinsic origin of the capsaicin-sensitive innervation of rat duodenum: possible involvement of calcitonin gene-related peptide (CGRP) in the capsaicin-induced activation of intramural non-adrenergic non-cholinergic neurons.
Naunyn Schmiedebergs Arch Pharmacol1986https://conductscience.org/library/papers/3491329PubMed
2,479,444Modulation of neurotransmission in the guinea-pig vas deferens by capsaicin: involvement of calcitonin gene-related peptide and substance P.Br J Pharmacol1989https://conductscience.org/library/papers/2479444PubMed
2,442,628Involvement of substance P in the excitatory action of GABAA agonists on cholinergic neurons in the guinea-pig ileum.Naunyn Schmiedebergs Arch Pharmacol1987https://conductscience.org/library/papers/2442628PubMed
2,431,327A pharmacological and immunohistochemical study of the splanchnic innervation of ileal longitudinal muscle in the toad Bufo marinus.Naunyn Schmiedebergs Arch Pharmacol1986https://conductscience.org/library/papers/2431327PubMed
1,884,100Prejunctional modulatory action of neuropeptide Y on responses due to antidromic activation of peripheral terminals of capsaicin-sensitive sensory nerves in the isolated guinea-pig ileum.Br J Pharmacol1991https://conductscience.org/library/papers/1884100PubMed
1,422,598Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin.Br J Pharmacol1992https://conductscience.org/library/papers/1422598PubMed
1,383,834CP-96,345, a non-peptide antagonist of substance P: I. Effects on the actions mediated by substance P and related tachykinins on the guinea-pig ileum and rabbit jejunum.Naunyn Schmiedebergs Arch Pharmacol1992https://conductscience.org/library/papers/1383834PubMed
522,896Capsaicin-sensitive innervation of the guinea-pig taenia caeci.Naunyn Schmiedebergs Arch Pharmacol1979https://conductscience.org/library/papers/522896PubMed
481,610Evidence that axons containing substance P in the guinea-pig ileum are of intrinsic origin.Naunyn Schmiedebergs Arch Pharmacol1979https://conductscience.org/library/papers/481610PubMed
93,705Longitudinal contraction of isolated guinea-pig ileum induced by rapid cooling.Naunyn Schmiedebergs Arch Pharmacol1979https://conductscience.org/library/papers/93705PubMed
31,571The site of action of capsaicin on the guinea-pig isolated ileum.Naunyn Schmiedebergs Arch Pharmacol1978https://conductscience.org/library/papers/31571PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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