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Paper · 7535342

Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells.

Patel DD and 6 others. J Exp Med, 1995. Cited by 129 papers, by iCite.

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ConductScience Library. Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells. Papers, record 7535342. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7535342

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells.
PubMed
Journal
J Exp Med
PubMed
Year
1995
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
129
iCite
Relative citation ratio, by iCite
2.59
iCite
Revised in PubMed
2019-05-08
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Patel DDD D
2Wee SFS F
3Whichard LPL P
4Bowen MAM A
5Pesando JMJ M
6Aruffo AA
7Haynes BFB F

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antigens, CDMajor topic
Antigens, Differentiation, T-LymphocyteMajor topic
GlycoproteinsMajor topic
Thymus GlandMajor topic
Activated-Leukocyte Cell Adhesion Molecule
Antibodies, Monoclonal
Antigens, Surface
Child
Epithelium
Epitopes
Fibroblasts
Humans
Molecular Weight
Organ Specificity
Recombinant Fusion Proteins

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
CA28936NCI NIH HHSUnited StatesR01CA028936PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,790,625A novel human T cell antigen preferentially expressed on mature T cells and shared by both well and poorly differentiated B cell leukemias and lymphomas.J Immunol1981https://conductscience.org/library/papers/6790625PubMed
27,923,388Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.Cell Immunol1994https://conductscience.org/library/papers/7923388PubMed
36,982,759Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex.Cell1982https://conductscience.org/library/papers/6982759PubMed
46,863,545Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene.J Clin Invest1983https://conductscience.org/library/papers/6863545PubMed
53,874,195In vitro growth and phenotypic characterization of mesodermal-derived and epithelial components of normal and abnormal human thymus.Hum Immunol1985https://conductscience.org/library/papers/3874195PubMed
63,456,179Isolation of cowpox virus A-type inclusions and characterization of their major protein component.Virology1986https://conductscience.org/library/papers/3456179PubMed
73,491,146Antibody-induced antigenic modulation is antigen dependent: characterization of 22 proteins on a malignant human B cell line.J Immunol1986https://conductscience.org/library/papers/3491146PubMed
83,098,838Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.J Immunol1987https://conductscience.org/library/papers/3098838PubMed
93,116,085Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation.J Immunol1987https://conductscience.org/library/papers/3116085PubMed
102,895,1502H1--a novel antigen involved in T lymphocyte triggering.J Immunol1988https://conductscience.org/library/papers/2895150PubMed

1 to 10 of 28

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Cited by44

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 129 citations.

PMIDTitleJournalYearIn PapersSource
39,840,036Ligands of CD6: roles in the pathogenesis and treatment of cancer.Front Immunol2024https://conductscience.org/library/papers/39840036PubMed
39,369,131AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine.Cell Mol Life Sci2024https://conductscience.org/library/papers/39369131PubMed
38,790,044The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling.Cell Commun Signal2024https://conductscience.org/library/papers/38790044PubMed
38,139,340CD6 and Its Interacting Partners: Newcomers to the Block of Cancer Immunotherapies.Int J Mol Sci2023https://conductscience.org/library/papers/38139340PubMed
37,514,028Optimization and Characterization of Novel ALCAM-Targeting Antibody Fragments for Transepithelial Delivery.Pharmaceutics2023https://conductscience.org/library/papers/37514028PubMed
36,859,431Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis.Nat Commun2023https://conductscience.org/library/papers/36859431PubMed
34,680,335The Clinical and Theranostic Values of Activated Leukocyte Cell Adhesion Molecule (ALCAM)/CD166 in Human Solid Cancers.Cancers (Basel)2021https://conductscience.org/library/papers/34680335PubMed
34,070,159Contribution of Evolutionary Selected Immune Gene Polymorphism to Immune-Related Disorders: The Case of Lymphocyte Scavenger Receptors CD5 and CD6.Int J Mol Sci2021https://conductscience.org/library/papers/34070159PubMed
32,907,880Interactions of ferritin with scavenger receptor class A members.J Biol Chem2020https://conductscience.org/library/papers/32907880PubMed
32,098,784Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.Life Sci Alliance2020https://conductscience.org/library/papers/32098784PubMed

1 to 10 of 44

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CD6923PubTator's text mininghttps://conductscience.org/library/genes/923NCBI Gene
TRBV20OR9-26,962PubTator's text mininghttps://conductscience.org/library/genes/6962NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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