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Paper7562004

Growth inhibition of rat glioma cells in vitro and in vivo by aspirin.

Aas AT and 3 others. J Neurooncol, 1995. Cited by 34 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Growth inhibition of rat glioma cells in vitro and in vivo by aspirin. Papers, record 7562004. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7562004

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin.
PubMed
Journal
J Neurooncol
PubMed
Year
1995
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
34
iCite
Relative citation ratio, by iCite
0.96
iCite
Revised in PubMed
2019-09-09
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Aas ATA T
2Tønnessen TIT I
3Brun AA
4Salford LGL G

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Anti-Inflammatory Agents, Non-SteroidalMajor topic
AspirinMajor topic
Brain NeoplasmsMajor topic
GliomaMajor topic
Adenosine Triphosphate
Animals
Cell Division
Female
Hydrogen-Ion Concentration
Indomethacin
Male
Neoplasm Proteins
Neoplasm Transplantation
Piroxicam
Rats
Rats, Inbred F344
Salicylates
Tumor Cells, Cultured

Source PubMed

References31

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
13,373,288Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model.J Neurosurg1988https://conductscience.org/library/papers/3373288PubMed
22,873,353Biochemical investigation of human tumours in vivo with phosphorus-31 magnetic resonance spectroscopy.Lancet1986https://conductscience.org/library/papers/2873353PubMed
32,545,340Acid pH in tumors and its potential for therapeutic exploitation.Cancer Res1989https://conductscience.org/library/papers/2545340PubMed
48,260,358Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment.Br J Cancer1993https://conductscience.org/library/papers/8260358PubMed
52,535,690Requirement of the Na+/H+ exchanger for tumor growth.Cancer Res1989https://conductscience.org/library/papers/2535690PubMed
66,095,096Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH.Nature1984https://conductscience.org/library/papers/6095096PubMed
73,918,045Mitogen-independent activation of Na+/H+ exchange in human epidermoid carcinoma A431 cells: regulation by medium osmolarity.J Cell Physiol1985https://conductscience.org/library/papers/3918045PubMed
8954,814Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse.Eur J Pharmacol1976https://conductscience.org/library/papers/954814PubMed
93,418,382Ten-year survival among patients with supratentorial astrocytomas grade III and IV.J Neurosurg1988https://conductscience.org/library/papers/3418382PubMed
102,703,970Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport.J Pharmacol Exp Ther1989https://conductscience.org/library/papers/2703970PubMed
117,012,859Intracellular pH.Physiol Rev1981https://conductscience.org/library/papers/7012859PubMed
128,729Intracellular pH and activation of sea urchin eggs after fertilisation.Nature1976https://conductscience.org/library/papers/8729PubMed
133,515,010Reductive effect of aspirin treatment on primary tumor growth and metastasis of implanted fibrosarcoma in rats.J Natl Cancer Inst1986https://conductscience.org/library/papers/3515010PubMed
142,844,806Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells.J Biol Chem1988https://conductscience.org/library/papers/2844806PubMed
156,961,450Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6961450PubMed
163,017,962The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange.J Biol Chem1986https://conductscience.org/library/papers/3017962PubMed
173,403,517Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport.J Biol Chem1988https://conductscience.org/library/papers/3403517PubMed
183,624,315Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH.J Cell Physiol1987https://conductscience.org/library/papers/3624315PubMed
193,624,314Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange.J Cell Physiol1987https://conductscience.org/library/papers/3624314PubMed
2042,779Regulation of chloride in quiescent sheep-heart Purkinje fibres studied using intracellular chloride and pH-sensitive micro-electrodes.J Physiol1979https://conductscience.org/library/papers/42779PubMed

See all 31 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 34 citations.

PMIDTitleJournalYearIn PapersSource
40,651,674Repurposing neurological drugs for brain cancer therapeutics: A systematic approach to identify charged molecules for affinity-based local drug delivery systems.Int J Pharm2025https://conductscience.org/library/papers/40651674PubMed
31,637,020The interrelationship between cerebral ischemic stroke and glioma: a comprehensive study of recent reports.Signal Transduct Target Ther2019https://conductscience.org/library/papers/31637020PubMed
30,443,448Survival as a Function of Nonsteroidal Anti-inflammatory Drug Use in Patients with Glioblastoma.Cureus2018https://conductscience.org/library/papers/30443448PubMed
26,342,455Increasing the endogenous NO level causes catalase inactivation and reactivation of intercellular apoptosis signaling specifically in tumor cells.Redox Biol2015https://conductscience.org/library/papers/26342455PubMed
21,302,177Modulation of glioma risk and progression by dietary nutrients and antiinflammatory agents.Nutr Cancer2011https://conductscience.org/library/papers/21302177PubMed
18,158,574Anti-tumor effect of non-steroidal anti-inflammatory drugs on human ovarian cancers.Pathol Oncol Res2007https://conductscience.org/library/papers/18158574PubMed
17,504,931Preoperative thrombocytosis predicts poor survival in patients with glioblastoma.Neuro Oncol2007https://conductscience.org/library/papers/17504931PubMed
15,803,368Inhibition of cell invasion by indomethacin on glioma cell lines: in vitro study.J Neurooncol2005https://conductscience.org/library/papers/15803368PubMed
15,015,658Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089.J Neurooncol2004https://conductscience.org/library/papers/15015658PubMed
14,693,827The eicosanoid cascade: possible role in gliomas and meningiomas.J Clin Pathol2004https://conductscience.org/library/papers/14693827PubMed
10,902,853Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.J Neurooncol2000https://conductscience.org/library/papers/10902853PubMed
9,804,370p53 and brain tumors: from gene mutations to gene therapy.Brain Pathol1998https://conductscience.org/library/papers/9804370PubMed
7,673,979The RG2 rat glioma model.J Neurooncol1995https://conductscience.org/library/papers/7673979PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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