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Paper · 7610045

Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases.

Tuusa J and 2 others. Nucleic Acids Res, 1995. Cited by 22 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases. Papers, record 7610045. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7610045

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases.
PubMed
Journal
Nucleic Acids Res
PubMed
Year
1995
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
22
iCite
Relative citation ratio, by iCite
0.38
iCite
Revised in PubMed
2020-12-09
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Tuusa JJ
2Uitto LL
3Syväoja JEJ E

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cell DivisionMajor topic
DNA-Directed DNA PolymeraseMajor topic
Gene ExpressionMajor topic
Cell Cycle
DNA Polymerase I
DNA Polymerase II
DNA Repair
DNA Replication
G1 Phase
HeLa Cells
Humans
Nocodazole
RNA, Messenger
Resting Phase, Cell Cycle
S Phase

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References42

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
13,359,994Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.EMBO J1988https://conductscience.org/library/papers/3359994PubMed
22,423,078Sequence of human DNA polymerase beta mRNA obtained through cDNA cloning.Biochem Biophys Res Commun1986https://conductscience.org/library/papers/2423078PubMed
33,211,134Gene expression of human DNA polymerase alpha during cell proliferation and the cell cycle.Mol Cell Biol1988https://conductscience.org/library/papers/3211134PubMed
42,563,372Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen.J Biol Chem1989https://conductscience.org/library/papers/2563372PubMed
52,651,430Methyl-directed DNA mismatch correction.J Biol Chem1989https://conductscience.org/library/papers/2651430PubMed
62,710,127Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.Mol Cell Biol1989https://conductscience.org/library/papers/2710127PubMed
72,569,465Regulation of proliferating cell nuclear antigen during the cell cycle.J Biol Chem1989https://conductscience.org/library/papers/2569465PubMed
82,406,268Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme.J Biol Chem1990https://conductscience.org/library/papers/2406268PubMed
92,169,349A third essential DNA polymerase in S. cerevisiae.Cell1990https://conductscience.org/library/papers/2169349PubMed
102,005,899Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells.Mol Cell Biol1991https://conductscience.org/library/papers/2005899PubMed

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 22 citations.

PMIDTitleJournalYearIn PapersSource
12,087,186The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells.Nucleic Acids Res2002https://conductscience.org/library/papers/12087186PubMed
11,433,027E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2.Nucleic Acids Res2001https://conductscience.org/library/papers/11433027PubMed
11,058,115Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis.Nucleic Acids Res2000https://conductscience.org/library/papers/11058115PubMed
10,871,396Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta.Nucleic Acids Res2000https://conductscience.org/library/papers/10871396PubMed
10,215,605Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase epsilon.Biochem J1999https://conductscience.org/library/papers/10215605PubMed
9,443,964The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon.Nucleic Acids Res1998https://conductscience.org/library/papers/9443964PubMed
8,641,295DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication.EMBO J1996https://conductscience.org/library/papers/8641295PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
POLA15,422PubTator's text mininghttps://conductscience.org/library/genes/5422NCBI Gene
POLB5,423PubTator's text mininghttps://conductscience.org/library/genes/5423NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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