Paper · 7610045
Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases.
Tuusa J and 2 others. Nucleic Acids Res, 1995. Cited by 22 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases. Papers, record 7610045. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7610045
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases.
- PubMed
Topics15
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Cell Division | Major topic |
| DNA-Directed DNA Polymerase | Major topic |
| Gene Expression | Major topic |
| Cell Cycle | |
| DNA Polymerase I | |
| DNA Polymerase II | |
| DNA Repair | |
| DNA Replication | |
| G1 Phase | |
| HeLa Cells | |
| Humans | |
| Nocodazole | |
| RNA, Messenger | |
| Resting Phase, Cell Cycle | |
| S Phase |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References42
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 3,359,994 | Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. | EMBO J | 1988 | https://conductscience.org/library/papers/3359994 | PubMed |
| 2 | 2,423,078 | Sequence of human DNA polymerase beta mRNA obtained through cDNA cloning. | Biochem Biophys Res Commun | 1986 | https://conductscience.org/library/papers/2423078 | PubMed |
| 3 | 3,211,134 | Gene expression of human DNA polymerase alpha during cell proliferation and the cell cycle. | Mol Cell Biol | 1988 | https://conductscience.org/library/papers/3211134 | PubMed |
| 4 | 2,563,372 | Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen. | J Biol Chem | 1989 | https://conductscience.org/library/papers/2563372 | PubMed |
| 5 | 2,651,430 | Methyl-directed DNA mismatch correction. | J Biol Chem | 1989 | https://conductscience.org/library/papers/2651430 | PubMed |
| 6 | 2,710,127 | Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells. | Mol Cell Biol | 1989 | https://conductscience.org/library/papers/2710127 | PubMed |
| 7 | 2,569,465 | Regulation of proliferating cell nuclear antigen during the cell cycle. | J Biol Chem | 1989 | https://conductscience.org/library/papers/2569465 | PubMed |
| 8 | 2,406,268 | Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. | J Biol Chem | 1990 | https://conductscience.org/library/papers/2406268 | PubMed |
| 9 | 2,169,349 | A third essential DNA polymerase in S. cerevisiae. | Cell | 1990 | https://conductscience.org/library/papers/2169349 | PubMed |
| 10 | 2,005,899 | Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells. | Mol Cell Biol | 1991 | https://conductscience.org/library/papers/2005899 | PubMed |
1 to 10 of 42
See all 42 referencesCited by7
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 22 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 12,087,186 | The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells. | Nucleic Acids Res | 2002 | https://conductscience.org/library/papers/12087186 | PubMed |
| 11,433,027 | E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2. | Nucleic Acids Res | 2001 | https://conductscience.org/library/papers/11433027 | PubMed |
| 11,058,115 | Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. | Nucleic Acids Res | 2000 | https://conductscience.org/library/papers/11058115 | PubMed |
| 10,871,396 | Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta. | Nucleic Acids Res | 2000 | https://conductscience.org/library/papers/10871396 | PubMed |
| 10,215,605 | Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase epsilon. | Biochem J | 1999 | https://conductscience.org/library/papers/10215605 | PubMed |
| 9,443,964 | The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon. | Nucleic Acids Res | 1998 | https://conductscience.org/library/papers/9443964 | PubMed |
| 8,641,295 | DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication. | EMBO J | 1996 | https://conductscience.org/library/papers/8641295 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| POLA1 | 5,422 | PubTator's text mining | https://conductscience.org/library/genes/5422 | NCBI Gene |
| POLB | 5,423 | PubTator's text mining | https://conductscience.org/library/genes/5423 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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