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Paper7731995

Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.

Mitani K and 3 others. Proc Natl Acad Sci U S A, 1995. Cited by 194 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. Papers, record 7731995. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7731995

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1995
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
194
iCite
Relative citation ratio, by iCite
4.27
iCite
Revised in PubMed
2019-12-10
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Mitani KK
2Graham FLF L
3Caskey CTC T
4Kochanek SS

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adenoviruses, HumanMajor topic
DNA, ViralMajor topic
Genetic VectorsMajor topic
Helper VirusesMajor topic
Animals
Cell Line
Centrifugation, Density Gradient
Chlorocebus aethiops
DNA Replication
Defective Viruses
Humans
Kidney
Plasmids
Recombinant Proteins
Restriction Mapping
Transfection
beta-Galactosidase

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
1PO1HL51754NHLBI NIH HHSUnited StatesP01HL051754PubMed and NIH

Source NIH RePORTER

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,705,382A new technique for the assay of infectivity of human adenovirus 5 DNA.Virology1973https://conductscience.org/library/papers/4705382PubMed
28,090,727An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.Proc Natl Acad Sci U S A1994https://conductscience.org/library/papers/8090727PubMed
3205,653The structure and expression of two defective adenovirus 2/simian virus 40 hybrids.J Mol Biol1978https://conductscience.org/library/papers/205653PubMed
4206,726Enhanced infectivity of adenovirus type 2 DNA and a DNA-protein complex.J Virol1978https://conductscience.org/library/papers/206726PubMed
57,418,007Encapsidation of adenovirus 16 DNA is directed by a small DNA sequence at the left end of the genome.Cell1980https://conductscience.org/library/papers/7418007PubMed
66,265,937An unusual symmetric recombinant between adenovirus type 12 DNA and human cell DNA.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6265937PubMed
76,296,462Palindromic adenovirus type 5-simian virus 40 hybrid.J Virol1983https://conductscience.org/library/papers/6296462PubMed
86,303,701Uptake, fixation, and expression of foreign DNA in mammalian cells: the organization of integrated adenovirus DNA sequences.Curr Top Microbiol Immunol1982https://conductscience.org/library/papers/6303701PubMed
96,323,266Proof of recombination between viral and cellular genomes in human KB cells productively infected by adenovirus type 12: structure of the junction site in a symmetric recombinant (SYREC).Gene1983https://conductscience.org/library/papers/6323266PubMed
106,737,476Replication of adenovirus mini-chromosomes.J Mol Biol1984https://conductscience.org/library/papers/6737476PubMed
116,098,454Covalently closed circles of human adenovirus DNA are infectious.EMBO J1984https://conductscience.org/library/papers/6098454PubMed
122,983,341An adenovirus vector system used to express polyoma virus tumor antigens.Proc Natl Acad Sci U S A1985https://conductscience.org/library/papers/2983341PubMed
132,987,934Overproduction of the protein product of a nonselected foreign gene carried by an adenovirus vector.Proc Natl Acad Sci U S A1985https://conductscience.org/library/papers/2987934PubMed
142,827,008
SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat.
Mol Cell Biol1988https://conductscience.org/library/papers/2827008PubMed
151,652,278Herpes simplex virus for gene delivery to neurons.New Biol1991https://conductscience.org/library/papers/1652278PubMed
161,653,172Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.Genes Dev1991https://conductscience.org/library/papers/1653172PubMed
171,731,109cis and trans requirements for the selective packaging of adenovirus type 5 DNA.J Virol1992https://conductscience.org/library/papers/1731109PubMed
181,582,242Retroviral vectors.Curr Top Microbiol Immunol1992https://conductscience.org/library/papers/1582242PubMed
191,582,245Expression of heterologous sequences in adenoviral vectors.Curr Top Microbiol Immunol1992https://conductscience.org/library/papers/1582245PubMed
208,371,349Packaging capacity and stability of human adenovirus type 5 vectors.J Virol1993https://conductscience.org/library/papers/8371349PubMed

See all 22 references

Cited by75

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 194 citations.

PMIDTitleJournalYearIn PapersSource
40,181,545The road toward AAV-mediated gene therapy of Duchenne muscular dystrophy.Mol Ther2025https://conductscience.org/library/papers/40181545PubMed
40,156,191The deLIVERed promises of gene therapy: Past, present, and future of liver-directed gene therapy.Mol Ther2025https://conductscience.org/library/papers/40156191PubMed
38,646,933Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction.JCI Insight2024https://conductscience.org/library/papers/38646933PubMed
38,543,743Advances of Recombinant Adenoviral Vectors in Preclinical and Clinical Applications.Viruses2024https://conductscience.org/library/papers/38543743PubMed
36,206,378The use of adenoviral vectors in gene therapy and vaccine approaches.Genet Mol Biol2022https://conductscience.org/library/papers/36206378PubMed
35,752,626Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.Nat Commun2022https://conductscience.org/library/papers/35752626PubMed
32,785,089The Evolution of Gene Therapy in the Treatment of Metabolic Liver Diseases.Genes (Basel)2020https://conductscience.org/library/papers/32785089PubMed
31,944,286Retargeting adenoviruses for therapeutic applications and vaccines.FEBS Lett2020https://conductscience.org/library/papers/31944286PubMed
30,706,395Current Use of Adenovirus Vectors and Their Production Methods.Methods Mol Biol2019https://conductscience.org/library/papers/30706395PubMed
30,089,813Precision gene editing technology and applications in nephrology.Nat Rev Nephrol2018https://conductscience.org/library/papers/30089813PubMed
29,172,089Retargeted and detargeted adenovirus for gene delivery to the muscle.Virology2018https://conductscience.org/library/papers/29172089PubMed
26,280,081BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector.Gene Ther2016https://conductscience.org/library/papers/26280081PubMed
26,116,393Pacing the Heart with Genes: Recent Progress in Biological Pacing.Curr Cardiol Rep2015https://conductscience.org/library/papers/26116393PubMed
25,876,176Progress on adenovirus-vectored universal influenza vaccines.Hum Vaccin Immunother2015https://conductscience.org/library/papers/25876176PubMed
25,479,556Adenovirus-based vaccines against avian-origin H5N1 influenza viruses.Microbes Infect2015https://conductscience.org/library/papers/25479556PubMed
25,254,384The adenovirus genome contributes to the structural stability of the virion.Viruses2014https://conductscience.org/library/papers/25254384PubMed
24,999,918Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.Nat Commun2014https://conductscience.org/library/papers/24999918PubMed
24,155,386Switching a replication-defective adenoviral vector into a replication-competent, oncolytic adenovirus.J Virol2014https://conductscience.org/library/papers/24155386PubMed
23,496,671Prospects, promise and problems on the road to effective vaccines and related therapies for substance abuse.Expert Rev Vaccines2013https://conductscience.org/library/papers/23496671PubMed
23,202,501Advances and future challenges in recombinant adenoviral vectored H5N1 influenza vaccines.Viruses2012https://conductscience.org/library/papers/23202501PubMed

See all 75 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
GLB12,720PubTator's text mininghttps://conductscience.org/library/genes/2720

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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