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Paper · 77481

Studies on the release of histamine from isolated guinea pig mast cells stimulated by ionophore A23187 or by the anaphylactic reaction.

Pearce FL and 3 others. Naunyn Schmiedebergs Arch Pharmacol, 1978. Cited by 21 papers, by iCite.

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ConductScience Library. Studies on the release of histamine from isolated guinea pig mast cells stimulated by ionophore A23187 or by the anaphylactic reaction. Papers, record 77481. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/77481

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Studies on the release of histamine from isolated guinea pig mast cells stimulated by ionophore A23187 or by the anaphylactic reaction.
PubMed
Journal
Naunyn Schmiedebergs Arch Pharmacol
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
21
iCite
Relative citation ratio, by iCite
0.92
iCite
Revised in PubMed
2019-07-25
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Pearce FLF L
2Blum UU
3Poblete-Freundt GG
4Schmutzler WW

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AnaphylaxisMajor topic
Anti-Bacterial AgentsMajor topic
CalcimycinMajor topic
Histamine ReleaseMajor topic
Mast CellsMajor topic
Animals
Calcium
Cromolyn Sodium
Cyclic AMP
Guinea Pigs
In Vitro Techniques
Sympathomimetics
Theophylline

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References19

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
147,876The mechanism of basophil histamine release induced by antigen and by the calcium ionophore A23187.J Immunol1975https://conductscience.org/library/papers/47876PubMed
24,116,105The role of the alkaline earth ions in anaphylactic histamine secretion.J Physiol1972https://conductscience.org/library/papers/4116105PubMed
360,108Mechanism of action of disodium cromoglycate--mast cell calcium ion influx after a histamine-releasing stimulus.Biochem Pharmacol1976https://conductscience.org/library/papers/60108PubMed
449,313Stimulation and inhibition of histamine release from isolated rat mast cells. Dual effects of the ionophore A23187.Int Arch Allergy Appl Immunol1975https://conductscience.org/library/papers/49313PubMed
546,148A possible role for cyclic AMP in the regulation of histamine secretion and the action of cromoglycate.Biochem Pharmacol1975https://conductscience.org/library/papers/46148PubMed
6764,856Ionophore A23187. Solution conformations of the calcium complex and free acid deduced from proton and carbon-13 nuclear magnetic resonance studies.Biochemistry1976https://conductscience.org/library/papers/764856PubMed
74,126,372Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process.Nature1973https://conductscience.org/library/papers/4126372PubMed
8764,880Ionophores X537A and A23187. Effects on the permeability of lipid bimolecular membranes to dopamine and calcium.Biochim Biophys Acta1976https://conductscience.org/library/papers/764880PubMed
960,103Cyclic AMP independent inhibition by papaverine of histamine release induced by compound 48/80.Biochem Pharmacol1976https://conductscience.org/library/papers/60103PubMed
104,205,591Calcium-induced extrusion of secretory granules (exocytosis) in mast cells exposed to 48-80 or the ionophores A-23187 and X-537A.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4205591PubMed

1 to 10 of 19

See all 19 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 21 citations.

PMIDTitleJournalYearIn PapersSource
6,203,366Autacoid and beta-adrenergic agonist modulation of N-formylmethionyl-leucyl-phenylalanine evoked lysosomal enzyme release from human neutrophils.Agents Actions1984https://conductscience.org/library/papers/6203366PubMed
6,185,855Presence of functionally active beta-adrenoceptors in rat mast cells. Correlation between (--)[3H]-dihydroalprenolol binding and inhibition of histamine release.Naunyn Schmiedebergs Arch Pharmacol1982https://conductscience.org/library/papers/6185855PubMed
6,182,345Mast cell receptors controlling histamine release: influences on the mode of action of drugs used in the treatment of adverse drug reactions.Klin Wochenschr1982https://conductscience.org/library/papers/6182345PubMed
6,157,320Inhibition of histamine release induced by compound 48/80 and peptide 401 in the presence and absence of calcium. Implications for the mode of action of anti-allergic compounds.Agents Actions1980https://conductscience.org/library/papers/6157320PubMed
2,451,398Non cytotoxic guinea-pig mesenteric mast cell stimulation by protamine.Agents Actions1987https://conductscience.org/library/papers/2451398PubMed
88,887Release of heparin and histamine from guinea pig mast cells [proceedings].Agents Actions1979https://conductscience.org/library/papers/88887PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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