Paper · 77751

The use of hapten-polysaccharide conjugates for the induction of B-cell tolerance involving IgE responses. I. Preparation, characterization and specific tolerogenic activity of penicilloy l-substituted levans affecting IgE responses in normal and sensitized mice.

Moreno C and 2 others. Clin Exp Immunol, 1978. Cited by 20 papers, by iCite.

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ConductScience Library. The use of hapten-polysaccharide conjugates for the induction of B-cell tolerance involving IgE responses. I. Preparation, characterization and specific tolerogenic activity of penicilloy l-substituted levans affecting IgE responses in normal and sensitized mice. Papers, record 77751. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/77751

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The use of hapten-polysaccharide conjugates for the induction of B-cell tolerance involving IgE responses. I. Preparation, characterization and specific tolerogenic activity of penicilloy l-substituted levans affecting IgE responses in normal and sensitized mice.; PubMed
Journal: Clin Exp Immunol; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/77751/; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1541236/; PubMed
The journal: https://conductscience.org/library/journal-index/0057202; PubMed
Citations, by iCite: 20; iCite
Relative citation ratio, by iCite: 0.79; iCite
Revised in PubMed: 2018-11-13; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Moreno C	C
2	Hale C	C
3	Hewett R	R

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Haptens	Major topic
Immune Tolerance	Major topic
Immunoglobulin E	Major topic
Penicillin G	Major topic
Polysaccharides	Major topic
Animals
Antibody Specificity
B-Lymphocytes
Epitopes
Immunoglobulin M
Mice
Mice, Inbred CBA
Mice, Inbred DBA

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References43

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	10,172	Role of epitope density in the induction of immunity and tolerance with thymus-independent antigens. I. Studies with 2,4-dinitrophenyl conjugates in vitro.	Eur J Immunol	1975	https://conductscience.org/library/papers/10172	PubMed
2	820,800	Regulation of antibody response in different immunoglobulin classes. I. Selective suppression of anti-DNP IgE antibody response by preadministration of DNP-coupled mycobacterium.	J Immunol	1976	https://conductscience.org/library/papers/820800	PubMed
3	1,084,370	Generation of specific helper cells and suppressor cells in vitro for the IgE and IgG antibody responses.	J Immunol	1976	https://conductscience.org/library/papers/1084370	PubMed
4	1,086,248	Role of epitope density in the induction of immunity and tolerance with thymus-independent antigens. II. Studies with 2,4-dinitrophenyl conjugates in vivo.	Eur J Immunol	1975	https://conductscience.org/library/papers/1086248	PubMed
5	1,086,775	B cell tolerance induced by polymeric antigens. IV. Antigen-mediated inhibition of antibody-forming cells.	Eur J Immunol	1976	https://conductscience.org/library/papers/1086775	PubMed
6	1,116,878	PCA reactions with mouse antibodies in mice and rats.	Int Arch Allergy Appl Immunol	1975	https://conductscience.org/library/papers/1116878	PubMed
7	1,127,228	IgE antibody-specific abrogation of an established immune response in mice by modified antigens.	J Immunol	1975	https://conductscience.org/library/papers/1127228	PubMed
8	1,168,548	Effect of Nippostrongylus brasiliensis infection on anti-hapten IgE antibody response in the mouse. II. Mechanism of potentiation of the IgE antibody response to a heterologous hapten-carrier conjugate.	Cell Immunol	1975	https://conductscience.org/library/papers/1168548	PubMed
9	1,272,373	Isologous IgG-induced tolerance to benzyl penicilloyl.	Nature	1976	https://conductscience.org/library/papers/1272373	PubMed
10	13,930,142	Studies on the dimensions of the rabbit antibenzylpenicilloyl antibody-combing sites.	J Exp Med	1963	https://conductscience.org/library/papers/13930142	PubMed

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 20 citations.

None in this release.

Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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