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Paper · 10172

Role of epitope density in the induction of immunity and tolerance with thymus-independent antigens. I. Studies with 2,4-dinitrophenyl conjugates in vitro.

Desaymard C and 1 other. Eur J Immunol, 1975. Cited by 45 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Role of epitope density in the induction of immunity and tolerance with thymus-independent antigens. I. Studies with 2,4-dinitrophenyl conjugates in vitro. Papers, record 10172. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10172

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Role of epitope density in the induction of immunity and tolerance with thymus-independent antigens. I. Studies with 2,4-dinitrophenyl conjugates in vitro.
PubMed
Journal
Eur J Immunol
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
45
iCite
Relative citation ratio, by iCite
0.74
iCite
Revised in PubMed
2016-11-23
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Desaymard CC
2Feldmann MM

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
DinitrobenzenesMajor topic
Immune ToleranceMajor topic
NitrobenzenesMajor topic
Animals
Corynebacterium
Dextrans
Dose-Response Relationship, Immunologic
Immunoglobulin M
Kinetics
Mice
Mice, Inbred CBA
Peptides
Polysaccharides, Bacterial
Streptococcus pneumoniae
Structure-Activity Relationship

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 45 citations.

PMIDTitleJournalYearIn PapersSource
31,836,655Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help.J Immunol2020https://conductscience.org/library/papers/31836655PubMed
6,209,210Induction of tolerance by haptenated liposomes carrying mouse erythrocyte membrane glycoprotein.Immunology1984https://conductscience.org/library/papers/6209210PubMed
6,157,774Defective B cell tolerance in adult (NZB X MZW)F1 mice.J Exp Med1980https://conductscience.org/library/papers/6157774PubMed
2,683,163Membrane Ig-mediated triggering of B cell tolerance and B cell clonal expansion: implications for rheumatoid factor production in rheumatoid synovitis.Springer Semin Immunopathol1989https://conductscience.org/library/papers/2683163PubMed
391,701Anti-DNP antibody responses to DNP-histone H1 in mice.Immunology1979https://conductscience.org/library/papers/391701PubMed
311,343Stimulation of T-independent antibody responses by hapten-lipopolysaccharides without repeating polymeric structure.Infect Immun1979https://conductscience.org/library/papers/311343PubMed
77,751
The use of hapten-polysaccharide conjugates for the induction of B-cell tolerance involving IgE responses. I. Preparation, characterization and specific tolerogenic activity of penicilloy l-substituted levans affecting IgE responses in normal and sensitized mice.
Clin Exp Immunol1978https://conductscience.org/library/papers/77751PubMed
59,360Induction if immunological tolerance to the major antigenic determinant of penicillin: a therapeutic approach to penicillin allergy.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/59360PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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