Paper8017
Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor of cathepsin B1.
Fräki JE. Arch Dermatol Res (1975), 1976. Cited by 38 papers, by iCite.
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ConductScience Library. Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor of cathepsin B1. Papers, record 8017. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/8017
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor of cathepsin B1.
- PubMed
Topics10
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Cathepsins | Major topic |
| Peptide Hydrolases | Major topic |
| Skin | Major topic |
| Benzoylarginine-2-Naphthylamide | |
| Chromatography, Liquid | |
| Hemoglobins | |
| Humans | |
| Hydrogen-Ion Concentration | |
| Hydrolysis | |
| Molecular Weight |
Source PubMed
References34
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,207,388 | Cathepsin B1. A lysosomal enzyme that degrades native collagen. | Biochem J | 1974 | https://conductscience.org/library/papers/4207388 | PubMed |
| 2 | 4,651,135 | The nature of the collagenolytic cathepsin of rat liver and its distribution in other rat tissues. | Biochem J | 1972 | https://conductscience.org/library/papers/4651135 | PubMed |
| 3 | 5,344,610 | Unsuitability of leucine naphthylamide for the histochemical demonstration of lysosomal proteolytic activity. | Nature | 1969 | https://conductscience.org/library/papers/5344610 | PubMed |
| 4 | 1,101,833 | Immunocytochemical localization of cathepsin D in rabbit skin. | Arch Dermatol | 1975 | https://conductscience.org/library/papers/1101833 | PubMed |
| 5 | 4,820,680 | The role of neutral proteinase and cathepsin D in turpentine-induced inflammation. | J Invest Dermatol | 1974 | https://conductscience.org/library/papers/4820680 | PubMed |
| 6 | 4,262,591 | Human skin proteases. | Arch Dermatol Forsch | 1972 | https://conductscience.org/library/papers/4262591 | PubMed |
| 7 | 14,292,834 | FURTHER PURIFICATION OF A PROTEASE INHIBITOR FROM RABBIT SKIN WITH HEALING INFLAMMATION. | Biochim Biophys Acta | 1965 | https://conductscience.org/library/papers/14292834 | PubMed |
| 9 | 5,021,576 | Human skin proteases. Differential extraction of proteases and of endogenous protease inhibitors. | Arch Dermatol Forsch | 1972 | https://conductscience.org/library/papers/5021576 | PubMed |
| 10 | 5,549,596 | Purification and properties of cathepsin D from bovine utrus. | J Biol Chem | 1971 | https://conductscience.org/library/papers/5549596 | PubMed |
| 11 | 5,043,176 | Human skin proteases. Fractionation and characterization. | Arch Dermatol Forsch | 1972 | https://conductscience.org/library/papers/5043176 | PubMed |
| 12 | 5,167,876 | Cathepsin B' in the thyroid gland. | Acta Chem Scand | 1971 | https://conductscience.org/library/papers/5167876 | PubMed |
| 13 | 14,462,361 | The purification and properties of a proteolytic enzyme, rabbit cathepsin E, and further studies on rabbit cathepsin D. | Biochem J | 1962 | https://conductscience.org/library/papers/14462361 | PubMed |
| 14 | 4,429,705 | Purification and characterization of rat liver lysosomal cathepsin B2. | Biochim Biophys Acta | 1974 | https://conductscience.org/library/papers/4429705 | PubMed |
| 15 | 1,122,298 | Improved purification of cathepsin B1 and cathepsin B2. | Biochim Biophys Acta | 1975 | https://conductscience.org/library/papers/1122298 | PubMed |
| 16 | 4,824,207 | Human placental cathepsin B1. Isolation and some physical properties. | Biochem J | 1974 | https://conductscience.org/library/papers/4824207 | PubMed |
| 17 | 4,423,493 | The purification of bovine cathepsin B1 and its mode of action on bovine collagens. | Biochem J | 1974 | https://conductscience.org/library/papers/4423493 | PubMed |
| 18 | 4,435,103 | A carbohydrate inhibitor of cathepsin B activity associated with haptoglobin. | Experientia | 1974 | https://conductscience.org/library/papers/4435103 | PubMed |
| 19 | 4,198,623 | Inhibition by alpha-macroglobulin and other serum proteins. | Biochem J | 1973 | https://conductscience.org/library/papers/4198623 | PubMed |
| 20 | 14,434,765 | The isolation and properties of a proteolytic enzyme, cathepsin D, from bovine spleen. | Biochem J | 1960 | https://conductscience.org/library/papers/14434765 | PubMed |
| 21 | 242,173 | alpha-N-benzoylarginine-2-naphthylamide hydrolase (cathepsin B1 ?) from rat skin. II. Purification of the enzyme and demonstration of two inhibitors in the skin. | Acta Chem Scand B | 1975 | https://conductscience.org/library/papers/242173 | PubMed |
Cited by7
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 38 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 28,094,448 | Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era. | Med Res Rev | 2018 | https://conductscience.org/library/papers/28094448 | PubMed |
| 8,215,586 | Detection and characterization of endogenous protease associated with desquamation of stratum corneum. | Arch Dermatol Res | 1993 | https://conductscience.org/library/papers/8215586 | PubMed |
| 3,530,141 | Serine proteinases in human cutaneous mastocytosis. | Arch Dermatol Res | 1986 | https://conductscience.org/library/papers/3530141 | PubMed |
| 900,989 | Inhibition of human skin proteinases by chloroquine, dapsone and sulfapyridine. | Arch Dermatol Res (1975) | 1977 | https://conductscience.org/library/papers/900989 | PubMed |
| 736,607 | Lymphocyte stimulation in vitro by proteinases and its augmentation with a proteinase binding factor from human skin. | Arch Dermatol Res | 1978 | https://conductscience.org/library/papers/736607 | PubMed |
| 21,851 | Factors affecting germination of Trichophyton mentagrophytes arthrospores. | Infect Immun | 1977 | https://conductscience.org/library/papers/21851 | PubMed |
| 9,031 | Human skin proteases. Fractionation of psoriasis scale proteases and separation of a plasminogen activator and a histone hydrolysing protease. | Arch Dermatol Res (1975) | 1976 | https://conductscience.org/library/papers/9031 | PubMed |
Genes3
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CTSB | 1,508 | PubTator's text mining | https://conductscience.org/library/genes/1508 | NCBI Gene |
| CTSD | 1,509 | PubTator's text mining | https://conductscience.org/library/genes/1509 | NCBI Gene |
| CTSZ | 1,522 | PubTator's text mining | https://conductscience.org/library/genes/1522 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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