ConductScience.org, home

Paper80453

Antibody-linked cytotoxic agents in the treatment of cancer: current status and future prospects.

Ghose T and 1 other. J Natl Cancer Inst, 1978. Cited by 157 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Antibody-linked cytotoxic agents in the treatment of cancer: current status and future prospects. Papers, record 80453. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/80453

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antibody-linked cytotoxic agents in the treatment of cancer: current status and future prospects.
PubMed
Journal
J Natl Cancer Inst
PubMed
Year
1978
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
157
iCite
Relative citation ratio, by iCite
4.65
iCite
Revised in PubMed
2004-11-17
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Ghose TT
2Blair AHA H

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibodies, NeoplasmMajor topic
Antineoplastic AgentsMajor topic
NeoplasmsMajor topic
Alkylating Agents
Animals
Antibiotics, Antineoplastic
Antibody Specificity
Antigens, Neoplasm
Antimetabolites, Antineoplastic
Bacterial Toxins
Drug Resistance
Epitopes
Histocompatibility Antigens
Humans
Immunity
Methods
Phospholipases
Plant Proteins

Source PubMed

Cited by28

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 157 citations.

PMIDTitleJournalYearIn PapersSource
38,953,775Evolution of Pyrrolysyl-tRNA Synthetase: From Methanogenesis to Genetic Code Expansion.Chem Rev2024https://conductscience.org/library/papers/38953775PubMed
28,134,797Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.Molecules2017https://conductscience.org/library/papers/28134797PubMed
18,508,155Use of antibodies and immunoconjugates for the therapy of more accessible cancers.Adv Drug Deliv Rev2008https://conductscience.org/library/papers/18508155PubMed
7,284,242A vindesine-anti-CEA conjugate cytotoxic for human cancer cells in vitro.Br J Cancer1981https://conductscience.org/library/papers/7284242PubMed
7,207,602Directing toxins to cancer cells.Nature1981https://conductscience.org/library/papers/7207602PubMed
6,996,771Monoclonal antibodies as tools in hematology.Blut1980https://conductscience.org/library/papers/6996771PubMed
6,988,099Oncostatic-antibody complexes in chemotherapy.Cancer Chemother Pharmacol1980https://conductscience.org/library/papers/6988099PubMed
6,968,912Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6968912PubMed
6,952,214
A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies.
Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6952214PubMed
6,950,410Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6950410PubMed
6,925,984Inhibition of a mouse hepatoma by the alkylating agent Trenimon linked to immunoglobulins.Cancer Immunol Immunother1982https://conductscience.org/library/papers/6925984PubMed
6,821,632Localisation and toxicity study of a vindesine-anti-CEA conjugate in patients with advanced cancer.Br J Cancer1983https://conductscience.org/library/papers/6821632PubMed
6,804,591In vivo therapy of a murine B cell tumor (BCL1) using antibody-ricin A chain immunotoxins.J Exp Med1982https://conductscience.org/library/papers/6804591PubMed
6,586,198Antigenicity and drug susceptibility of human osteogenic sarcoma cells "escaping" a cytotoxic methotrexate-albumin-monoclonal antibody conjugate.Br J Cancer1984https://conductscience.org/library/papers/6586198PubMed
6,350,169Cytotoxic effect of anti-idiotype antibody-chlorambucil conjugates against human lymphoblastoid cells.Immunology1983https://conductscience.org/library/papers/6350169PubMed
6,205,782Daunomycin-arachidonic acid complex as a potential new antitumor agent.Cancer Chemother Pharmacol1984https://conductscience.org/library/papers/6205782PubMed
6,183,764Human tumor-associated antigens identified by monoclonal antibodies.Springer Semin Immunopathol1982https://conductscience.org/library/papers/6183764PubMed
6,165,996Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6165996PubMed
3,929,932Monoclonal antibodies in clinical medicine.Br Med J (Clin Res Ed)1985https://conductscience.org/library/papers/3929932PubMed
3,847,291Conjugation of methotrexate to IgG antibodies and their F(ab)2 fragments and the effect of conjugated methotrexate on tumor growth in vivo.Cancer Immunol Immunother1985https://conductscience.org/library/papers/3847291PubMed

See all 28 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/80453

GET https://conductscience.org/api/papers/v1/80453/cited_by?page=2