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Paper82971

Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis.

Hurley JN and 4 others. Proc Natl Acad Sci U S A, 1978. Cited by 55 papers, by iCite.

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ConductScience Library. Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis. Papers, record 82971. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/82971

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
55
iCite
Relative citation ratio, by iCite
1.35
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hurley JNJ N
2Fu SMS M
3Kunkel HGH G
4McKenna GG
5Scharff MDM D

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antigens, NeoplasmMajor topic
Leukemia, LymphoidMajor topic
Aged
Cell Line
Clone Cells
Epitopes
Female
Fluorescent Antibody Technique
Hemagglutination Tests
Humans
Immunoglobulins
Middle Aged

Source PubMed

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,279,138Biochemical and morphological observations on lymphocytes in continuous cell culture from a patient with chronic lymphocytic leukemia.Acta Haematol1974https://conductscience.org/library/papers/4279138PubMed
24,186,919Immunoglobulin production in synchronized cultures of human hematopoietic cell lines. I. Variation of cellular immunoglobulin level with the generation cycle.J Immunol1969https://conductscience.org/library/papers/4186919PubMed
34,346,033Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4346033PubMed
44,363,409Epstein-barr virus-negative human malignant T-cell lines.J Exp Med1974https://conductscience.org/library/papers/4363409PubMed
54,612,522Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone-marrow-derived lymphocytes.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4612522PubMed
64,625,122Cloning of mouse myeloma cells and detection of rare variants.J Cell Physiol1972https://conductscience.org/library/papers/4625122PubMed
762,018Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes.J Exp Med1976https://conductscience.org/library/papers/62018PubMed
8782,729Immunoglobulin expression of cells from human lymphoblastoid lines. III. Cell cycle phase and surface immunoglobulin expression.Cell Immunol1976https://conductscience.org/library/papers/782729PubMed
9803,528Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes.J Immunol1975https://conductscience.org/library/papers/803528PubMed
1114,332,483SIMPLIFIED MYELOPEROXIDASE STAIN USING BENZIDINE DIHYDROCHLORIDE.Blood1965https://conductscience.org/library/papers/14332483PubMed
12163,658Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome.Blood1975https://conductscience.org/library/papers/163658PubMed
13165,156Classification and biological nature of established human hematopoietic cell lines.Int J Cancer1975https://conductscience.org/library/papers/165156PubMed
14197,411Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukaemia cell line.Nature1977https://conductscience.org/library/papers/197411PubMed
15344,797Immunologic characterization of hairy cell leukemias in continuous culture.J Immunol1978https://conductscience.org/library/papers/344797PubMed
164,133,943Cellular localization of an Epstein-Barr virus (EBV)-associated complement-fixing antigen in producer and non-producer lymphoblastoid cell lines.Int J Cancer1973https://conductscience.org/library/papers/4133943PubMed
174,136,723Establishment and characteristics of two unique cell lines from patients with lymphosarcoma.Int J Cancer1974https://conductscience.org/library/papers/4136723PubMed
184,140,017Biology of the human malignant lymphomas. I. Establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas.Cancer1974https://conductscience.org/library/papers/4140017PubMed
194,167,883Detection of genetic antigens utilizing gamma globulins coupled to red blood cells.Nature1967https://conductscience.org/library/papers/4167883PubMed
204,182,344Limited periods of gene expression in immunoglobulin-synthesizing cells.Science1969https://conductscience.org/library/papers/4182344PubMed
214,339,260Are some human lymphoblastoid cell lines established from leukemic tissues actually derived from normal leukocytes?Cancer1972https://conductscience.org/library/papers/4339260PubMed

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 55 citations.

PMIDTitleJournalYearIn PapersSource
6,973,004Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains.J Exp Med1981https://conductscience.org/library/papers/6973004PubMed
6,795,627Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6795627PubMed
6,772,735Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N-termini and different C-termini.J Exp Med1980https://conductscience.org/library/papers/6772735PubMed
6,606,012A novel HLA-D/DR-like antigen specific for human B lymphoid cells. Biochemical evidence for similarity to but nonidentity with known HLA-D/DR antigens.J Exp Med1983https://conductscience.org/library/papers/6606012PubMed
6,480,829Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.J Clin Invest1984https://conductscience.org/library/papers/6480829PubMed
6,439,743Polyclonal immunoglobulin secretion in patients with common variable immunodeficiency using monoclonal B cell differentiation factors.J Clin Invest1984https://conductscience.org/library/papers/6439743PubMed
6,375,389Induction of maturation of human B-cell lymphomas in vitro. Morphologic changes in relation to immunoglobulin and DNA synthesis.Am J Pathol1984https://conductscience.org/library/papers/6375389PubMed
6,295,671Interaction of Epstein-Barr virus with leukaemic B cells in vitro. I. Abortive infection and rare cell line establishment from chronic lymphocytic leukaemic cells.Clin Exp Immunol1982https://conductscience.org/library/papers/6295671PubMed
6,289,318Dimer-size DNA circles in a leukemic cell immortalized with the Epstein-Barr virus.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6289318PubMed
6,256,462Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia.J Exp Med1980https://conductscience.org/library/papers/6256462PubMed
3,886,830Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers.J Exp Med1985https://conductscience.org/library/papers/3886830PubMed
3,263,462Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells.J Exp Med1988https://conductscience.org/library/papers/3263462PubMed
3,262,465The establishment of cell lines from chronic B cell leukaemias: evidence of leukaemic origin by karyotypic abnormalities and Ig gene rearrangement.Clin Exp Immunol1988https://conductscience.org/library/papers/3262465PubMed
2,156,585Establishment and characterization of a new Epstein-Barr virus transformed cell line from a human B cell lymphoma.Blut1990https://conductscience.org/library/papers/2156585PubMed
312,899Isolation and immunological characterization of a major surface glycoprotein (gp54) preferentially expressed on certain human B cells.J Exp Med1979https://conductscience.org/library/papers/312899PubMed
286,328Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/286328PubMed
230,517Human cell lines containing Epstein-Barr virus but distinct from the common B cell lymphoblastoid lines.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/230517PubMed
88,499Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells.J Exp Med1979https://conductscience.org/library/papers/88499PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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