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Paper62018

Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes.

Hough DW and 4 others. J Exp Med, 1976. Cited by 64 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes. Papers, record 62018. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/62018

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes.
PubMed
Journal
J Exp Med
PubMed
Year
1976
PubMed
Publication types
Case Reports, Journal Article
PubMed
Citations, by iCite
64
iCite
Relative citation ratio, by iCite
1.42
iCite
Revised in PubMed
2019-05-08
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hough DWD W
2Eady RPR P
3Hamblin TJT J
4Stevenson FKF K
5Stevenson GTG T

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibodies, Anti-IdiotypicMajor topic
B-LymphocytesMajor topic
Immunoglobulin MMajor topic
Leukemia, LymphoidMajor topic
Receptors, Antigen, B-CellMajor topic
Aged
Antibody Specificity
Epitopes
Female
Humans
Immunoglobulin Fab Fragments
Male
Methods

Source PubMed

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,089,708Identification of two populations of immunoglobulin-bearing lymphocytes in man.J Immunol1975https://conductscience.org/library/papers/1089708PubMed
21,262,783Mutant lines of guinea pig L2C leukemia. I. Deletion of Ia alloantigens is associated with a loss in immunogenicity of tumor-associated transplantation antigens.J Exp Med1976https://conductscience.org/library/papers/1262783PubMed
34,113,870Myeloma proteins as tumor-specific transplantation antigens.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4113870PubMed
44,115,135Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays.J Exp Med1972https://conductscience.org/library/papers/4115135PubMed
54,131,936Immunisation with antigen coupled to an immunosorbent.Nature1974https://conductscience.org/library/papers/4131936PubMed
64,138,880Idiotypic uniformity of cell surface immunoglobulin in chronic lymphocytic leukeima. Evidence for monoclonal proliferation.J Exp Med1974https://conductscience.org/library/papers/4138880PubMed
74,177,759Spectrum of ovine immunoglobulins.Proc Soc Exp Biol Med1968https://conductscience.org/library/papers/4177759PubMed
84,200,956Lymphocytes forming red cell rosettes in the cold in patients with chronic cold agglutinin disease.Blood1973https://conductscience.org/library/papers/4200956PubMed
94,511,918Syngeneic immune serum specifically inhibits the motility of tumour cells.Nat New Biol1973https://conductscience.org/library/papers/4511918PubMed
104,541,122Active suppression of immunoglobulin allotype synthesis. 3. Identification of T cells as responsible for suppression by cells from spleen, thymus, lymph node, and bone marrow.J Exp Med1973https://conductscience.org/library/papers/4541122PubMed
114,544,585Cell surface immunoglobulin. VII. Synthesis, shedding, and secretion of immunoglobulin by lymphoid cells of germ-free mice.J Exp Med1974https://conductscience.org/library/papers/4544585PubMed
124,554,455Variation in accessible cell surface immunoglobulin among antibody-firming cells.J Exp Med1972https://conductscience.org/library/papers/4554455PubMed
134,577,289Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia.Clin Exp Immunol1973https://conductscience.org/library/papers/4577289PubMed
144,604,559IgM in bone marrow-derived lymphocytes. Synthesis, surface deposition, turnover and carbohydrate composition in unstimulated mouse B cells.Eur J Immunol1974https://conductscience.org/library/papers/4604559PubMed
154,605,019Recovery of immunoglobulin removed from lymphocytic surfaces by proteolysis.Immunology1974https://conductscience.org/library/papers/4605019PubMed
164,609,460Early changes in immunoglobulin M synthesis after mitogenic stimulation of bone marrow derived lymphocytes.Biochemistry1974https://conductscience.org/library/papers/4609460PubMed
174,612,522Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone-marrow-derived lymphocytes.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4612522PubMed
1847,218Hypervariable regions, idiotypy, and the antibody-combining site.Adv Immunol1975https://conductscience.org/library/papers/47218PubMed
194,745,850Human tumor cell migration.J Natl Cancer Inst1973https://conductscience.org/library/papers/4745850PubMed
2047,617Antibody to a molecularly-defined antigen confined to a tumour cell surface.Nature1975https://conductscience.org/library/papers/47617PubMed

See all 29 references

Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 64 citations.

PMIDTitleJournalYearIn PapersSource
36,819,155Ars2-containing bispecific, Fab- and IgG1-format BAR-bodies to target DLBCL cells.EJHaem2023https://conductscience.org/library/papers/36819155PubMed
34,263,144The B-cell Receptor Autoantigen LRPAP1 Can Replace Variable Antibody Regions to Target Mantle Cell Lymphoma Cells.Hemasphere2021https://conductscience.org/library/papers/34263144PubMed
33,282,736Integration of the B-Cell Receptor Antigen Neurabin-I/SAMD14 Into an Antibody Format as New Therapeutic Approach for the Treatment of Primary CNS Lymphoma.Front Oncol2020https://conductscience.org/library/papers/33282736PubMed
27,114,517Targeting lymphoma with precision using semisynthetic anti-idiotype peptibodies.Proc Natl Acad Sci U S A2016https://conductscience.org/library/papers/27114517PubMed
25,271,313Three major uncertainties in the antibody therapy of cancer.Haematologica2014https://conductscience.org/library/papers/25271313PubMed
15,359,585How well can an idiotope peptide mimic replace its parent idiotype in a synthetic peptide vaccine?Pharm Res2004https://conductscience.org/library/papers/15359585PubMed
8,222,331Characterization of a human monoclonal autoantibody directed to cardiolipin/beta 2 glycoprotein I produced by chronic lymphocytic leukaemia B cells.Clin Exp Immunol1993https://conductscience.org/library/papers/8222331PubMed
7,192,154Preliminary experience in treating lymphocytic leukaemia with antibody to immunoglobulin idiotypes on the cell surfaces.Br J Cancer1980https://conductscience.org/library/papers/7192154PubMed
7,049,456The assessment of anti-idiopathic antibodies as effective immunoregulatory probes in vivo.Clin Exp Immunol1982https://conductscience.org/library/papers/7049456PubMed
6,970,174Antigenic modulation of lymphocytic surface immunoglobulin yielding resistance to complement-mediated lysis. I. Characterization with syngeneic and xenogeneic complements.Immunology1981https://conductscience.org/library/papers/6970174PubMed
6,969,771Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes.J Exp Med1980https://conductscience.org/library/papers/6969771PubMed
6,809,124Immune guided missiles.Br Med J (Clin Res Ed)1982https://conductscience.org/library/papers/6809124PubMed
6,722,005Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody.Br J Cancer1984https://conductscience.org/library/papers/6722005PubMed
6,350,169Cytotoxic effect of anti-idiotype antibody-chlorambucil conjugates against human lymphoblastoid cells.Immunology1983https://conductscience.org/library/papers/6350169PubMed
6,175,455Cell-bound immunoglobulin on peripheral blood mononuclear cells of patients with myeloma.Clin Exp Immunol1981https://conductscience.org/library/papers/6175455PubMed
221,000Antibody-induced changes in levels of cyclic adenosine monophosphate in leukaemic lymphocytes.Br J Cancer1979https://conductscience.org/library/papers/221000PubMed
97,669Rescue of immunoglobulin secretion from human neoplastic lymphoid cells by somatic cell hybridization.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/97669PubMed
96,010Further studies of immunoglobulin synthesis by guinea pig leukaemic lymphocytes.Immunology1978https://conductscience.org/library/papers/96010PubMed
92,518Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.J Exp Med1979https://conductscience.org/library/papers/92518PubMed
82,971Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/82971PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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