Paper · 83204

Hypothesis: nonspecific polyclonal activation of memory B cells by antigen as a mechanism for the preservation of long term immunologic anamnesis.

Moticka EJ and 1 other. Cell Immunol, 1978. Cited by 22 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Hypothesis: nonspecific polyclonal activation of memory B cells by antigen as a mechanism for the preservation of long term immunologic anamnesis. Papers, record 83204. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/83204

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Hypothesis: nonspecific polyclonal activation of memory B cells by antigen as a mechanism for the preservation of long term immunologic anamnesis.; PubMed
Journal: Cell Immunol; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/83204/; PubMed
DOI: https://doi.org/10.1016/0008-8749(78)90237-x; PubMed
The journal: https://conductscience.org/library/journal-index/1246405; PubMed
Citations, by iCite: 22; iCite
Relative citation ratio, by iCite: 0.56; iCite
Revised in PubMed: 2019-07-20; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Moticka EJ	E J
2	Streilein JW	J W

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Epitopes	Major topic
Immunologic Memory	Major topic
Hypergammaglobulinemia
Immunoglobulin Fc Fragments
Immunoglobulins
Macrophages
Multiple Myeloma
Time Factors

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 22 citations.

PMID	Title	Journal	Year	In Papers	Source
41,502,006	SARS-CoV-2 mRNA Vaccination Leads to Transient Humoral and B Cell Bystander Responses in Adults.	Eur J Immunol	2026	https://conductscience.org/library/papers/41502006	PubMed
34,835,283	Longitudinal Dynamics of Human B-Cell Response at the Single-Cell Level in Response to Tdap Vaccination.	Vaccines (Basel)	2021	https://conductscience.org/library/papers/34835283	PubMed
31,968,262	Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics.	Cell Rep	2020	https://conductscience.org/library/papers/31968262	PubMed
7,389,209	Oligoclonal immunoglobulins and smooth muscle antibodies in arthritic joints.	Clin Exp Immunol	1980	https://conductscience.org/library/papers/7389209	PubMed
7,380,475	Sequential changes in serum immunoglobulin levels in young RFM mice with host-versus-graft disease.	Immunology	1980	https://conductscience.org/library/papers/7380475	PubMed
7,294,881	Immunological features of psoriasis. Effects of Ro-109359, concanavalin A, pokeweed mitogen, and methotrexate on cultivated lymphocytes.	Arch Dermatol Res	1981	https://conductscience.org/library/papers/7294881	PubMed
6,604,024	Nonspecific induction of immunoglobulin M antibodies to periodontal disease-associated microorganisms after polyclonal human B-lymphocyte activation by Fusobacterium nucleatum.	Infect Immun	1983	https://conductscience.org/library/papers/6604024	PubMed
6,603,301	Human B cell growth factors overcome T cell-mediated inhibition of specific antibody production: a possible mechanism for the exacerbation of autoimmune disease.	Clin Exp Immunol	1983	https://conductscience.org/library/papers/6603301	PubMed
6,433,575	Non-specific polyclonal antibody response induced by Mycoplasma pneumoniae.	Yale J Biol Med	1983	https://conductscience.org/library/papers/6433575	PubMed
6,299,636	Specific and non-specific B cell activation in measles and varicella.	Clin Exp Immunol	1983	https://conductscience.org/library/papers/6299636	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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