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Paper · 884018

Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods.

Birkhead JS and 1 other. Br Heart J, 1977. Cited by 94 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods. Papers, record 884018. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/884018

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods.
PubMed
Journal
Br Heart J
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
94
iCite
Relative citation ratio, by iCite
3.82
iCite
Revised in PubMed
2019-05-03
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Birkhead JSJ S
2Vaughan Williams EME M

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Atrioventricular NodeMajor topic
DisopyramideMajor topic
Heart AtriaMajor topic
Heart Conduction SystemMajor topic
Neural ConductionMajor topic
PyridinesMajor topic
Refractory Period, ElectrophysiologicalMajor topic
Adolescent
Adult
Aged
Arrhythmias, Cardiac
Atropine
Female
Heart
Heart Ventricles
Humans
Male
Middle Aged
Parasympathetic Nervous System

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References11

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,110,747A COMPARISON OF THE ANTIFIBRILLATORY ACTIONS AND EFFECTS ON INTRACELLULAR CARDIAC POTENTIALS OF PRONETHALOL, DISOPYRAMIDE AND QUINIDINE.Br J Pharmacol Chemother1963https://conductscience.org/library/papers/14110747PubMed
21,026,535Acute termination of cardiac arrhythmias with intravenous disopyramide.J Int Med Res1976https://conductscience.org/library/papers/1026535PubMed
31,026,529The pharmacokinetics of disopyramide following myocardial infarction with special reference to oral and intravenous dose regimens.J Int Med Res1976https://conductscience.org/library/papers/1026529PubMed
41,026,525The effect of disopyramide on in vivo measurement of monophasic action potential in canine heart muscle.J Int Med Res1976https://conductscience.org/library/papers/1026525PubMed
54,586,372Class 3 antiarrhythmic action in man. Observations from monophasic action potential recordings and amiodarone treatment.Br Heart J1973https://conductscience.org/library/papers/4586372PubMed
61,119,389Electrophysiologic effects of the antiarrhythmic agent disopyramide phosphate.Am J Cardiol1975https://conductscience.org/library/papers/1119389PubMed
753,057Effects of disopyramide on electrophysiological properties of specialized conduction system in man and on accessory atrioventricular pathway in Wolff-Parkinson-White syndrome.Br Heart J1975https://conductscience.org/library/papers/53057PubMed
84,762,159Effects of disopyramide on electrophysiological and mechanical properties of the heart.J Pharm Sci1973https://conductscience.org/library/papers/4762159PubMed
94,757,788Electrophysiological evaluation of disopyramide in man.Am Heart J1973https://conductscience.org/library/papers/4757788PubMed
10772,700Classification of antidysrhythmic drugs.Pharmacol Ther B1975https://conductscience.org/library/papers/772700PubMed

1 to 10 of 11

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Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 94 citations.

PMIDTitleJournalYearIn PapersSource
19,760,273Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.Naunyn Schmiedebergs Arch Pharmacol2010https://conductscience.org/library/papers/19760273PubMed
8,428,201Antiarrhythmic agents act differently on the activation phase of the ACh-response in guinea-pig atrial myocytes.Br J Pharmacol1993https://conductscience.org/library/papers/8428201PubMed
7,426,181Response of atrial flutter to overdrive atrial pacing and intravenous disopyramide phosphate, singly and in combination.Br Heart J1980https://conductscience.org/library/papers/7426181PubMed
7,407,521Potentially dangerous effect of disopyramide on atrioventricular conduction in a patient on digitalis.Br Med J1980https://conductscience.org/library/papers/7407521PubMed
6,849,716Selective blockade of retrograde fast pathway by intravenous disopyramide in paroxysmal supraventricular tachycardia mediated by dual atrioventricular nodal pathways.Br Heart J1983https://conductscience.org/library/papers/6849716PubMed
6,652,350Pharmacological mapping of regional effects in the rabbit heart of some new antiarrhythmic drugs.Br J Pharmacol1983https://conductscience.org/library/papers/6652350PubMed
6,161,824Efficacy of intravenous disopyramide in acute cardiac arrhythmias.Eur J Clin Pharmacol1981https://conductscience.org/library/papers/6161824PubMed
3,970,790Disopyramide induced second and third degree atrioventricular block in patients with bifascicular block. An acute stress test to predict atrioventricular block progression.Br Heart J1985https://conductscience.org/library/papers/3970790PubMed
3,893,488Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass. Comparison with disopyramide and digoxin in a randomised trial.Br Heart J1985https://conductscience.org/library/papers/3893488PubMed
3,718,795A new method for evaluating the effect of antiarrhythmic drugs on atrioventricular nodal conduction.Br Heart J1986https://conductscience.org/library/papers/3718795PubMed

1 to 10 of 18

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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