Paper92183

MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.

Zinkernagel RM and 1 other. Adv Immunol, 1979. Cited by 1,321 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Papers, record 92183. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/92183

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.; PubMed
Journal: Adv Immunol; PubMed
Year: 1979; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/92183/; PubMed
DOI: https://doi.org/10.1016/s0065-2776(08)60262-x; PubMed
The journal: https://conductscience.org/library/journal-index/0370425; PubMed
Citations, by iCite: 1,321; iCite
Relative citation ratio, by iCite: 28.5; iCite
Revised in PubMed: 2019-10-27; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Zinkernagel RM	R M
2	Doherty PC	P C

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cytotoxicity, Immunologic	Major topic
Epitopes	Major topic
Major Histocompatibility Complex	Major topic
T-Lymphocytes	Major topic
Animals
Antibodies
Antigens, Viral
Binding, Competitive
Chimera
Chromosome Mapping
Clone Cells
Gammaretrovirus
Humans
Isoantigens
Mice
Poxviridae
Rats
Receptors, Antigen, B-Cell
Species Specificity
Tumor Virus Infections

Source PubMed

Show 14 more topicsShow fewer topics

Cited by569

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,321 citations.

PMID	Title	Journal	Year	In Papers	Source
42,433,167	Diversity of the Major Histocompatibility Complex Region Among Seven Founders of the Crested Ibis Nipponia nippon in Japan.	Anim Sci J	2026	https://conductscience.org/library/papers/42433167	PubMed
40,045,373	A chimeric antigen receptor tailored to integrate complementary activation signals potentiates the antitumor activity of NK cells.	J Exp Clin Cancer Res	2025	https://conductscience.org/library/papers/40045373	PubMed
38,620,211	Current situation in the development of a preventive HIV vaccine.	Enferm Infecc Microbiol Clin	2005	https://conductscience.org/library/papers/38620211	PubMed
35,529,847	Transplant Tolerance, Not Only Clonal Deletion.	Front Immunol	2022	https://conductscience.org/library/papers/35529847	PubMed
34,960,628	Heterologous Immunity of Virus-Specific T Cells Leading to Alloreactivity: Possible Implications for Solid Organ Transplantation.	Viruses	2021	https://conductscience.org/library/papers/34960628	PubMed
34,061,023	Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link.	Elife	2021	https://conductscience.org/library/papers/34061023	PubMed
33,776,885	A Case Report of Central Nervous System Graft-Versus-Host Disease and Literature Review.	Front Neurol	2021	https://conductscience.org/library/papers/33776885	PubMed
33,729,394	Immunity, virus evolution, and effectiveness of SARS-CoV-2 vaccines.	Braz J Med Biol Res	2021	https://conductscience.org/library/papers/33729394	PubMed
32,287,595	References.	Perspect Med Virol	1986	https://conductscience.org/library/papers/32287595	PubMed
31,413,198	A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections.	Proc Natl Acad Sci U S A	2019	https://conductscience.org/library/papers/31413198	PubMed
31,385,169	Polymorphisms in major histocompatibility complex genes and its associations with milk quality in Murrah buffaloes.	Trop Anim Health Prod	2020	https://conductscience.org/library/papers/31385169	PubMed
31,001,278	Immunology's Coming of Age.	Front Immunol	2019	https://conductscience.org/library/papers/31001278	PubMed
29,181,831	Molecular guidance cues in the development of visual pathway.	Protein Cell	2018	https://conductscience.org/library/papers/29181831	PubMed
28,755,382	Tools to define the melanoma-associated immunopeptidome.	Immunology	2017	https://conductscience.org/library/papers/28755382	PubMed
28,211,522	Structure and polymorphisms of the major histocompatibility complex in the Oriental stork, Ciconia boyciana.	Sci Rep	2017	https://conductscience.org/library/papers/28211522	PubMed
27,475,804	Immunotherapy as a Potential Treatment for Chordoma: a Review.	Curr Oncol Rep	2016	https://conductscience.org/library/papers/27475804	PubMed
26,804,910	L-selectin Is Essential for Delivery of Activated CD8(+) T Cells to Virus-Infected Organs for Protective Immunity.	Cell Rep	2016	https://conductscience.org/library/papers/26804910	PubMed
26,373,575	PD-L1 and HLA Class I Antigen Expression and Clinical Course of the Disease in Intrahepatic Cholangiocarcinoma.	Clin Cancer Res	2016	https://conductscience.org/library/papers/26373575	PubMed
26,213,383	Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells.	Cell	2015	https://conductscience.org/library/papers/26213383	PubMed
25,876,770	T Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T Cells.	Clin J Am Soc Nephrol	2015	https://conductscience.org/library/papers/25876770	PubMed

Show 14 more cited byShow fewer cited bySee all 569 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
HLA-C	3,107	PubTator's text mining	https://conductscience.org/library/genes/3107

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

Grants
Trials
Comments and corrections
References
Drugs
Data

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/92183

GET https://conductscience.org/api/papers/v1/92183/cited_by?page=2

API reference For AI assistants