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Paper9234792

The endotoxin of Helicobacter pylori is a modulator of host-dependent gastritis.

Sakagami T and 8 others. Infect Immun, 1997. Cited by 62 papers, by iCite.

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ConductScience Library. The endotoxin of Helicobacter pylori is a modulator of host-dependent gastritis. Papers, record 9234792. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/9234792

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The endotoxin of Helicobacter pylori is a modulator of host-dependent gastritis.
PubMed
Journal
Infect Immun
PubMed
Year
1997
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
62
iCite
Relative citation ratio, by iCite
1.75
iCite
Revised in PubMed
2021-05-26
PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Sakagami TT
2Vella JJ
3Dixon MFM F
4O'Rourke JJ
5Radcliff FF
6Sutton PP
7Shimoyama TT
8Beagley KK
9Lee AA

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Gastritis, AtrophicMajor topic
Helicobacter pyloriMajor topic
LipopolysaccharidesMajor topic
Animals
Antibodies, Bacterial
Female
Helicobacter Infections
Immunization
Mice
Mice, Inbred C3H

Source PubMed

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,138,849Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides.J Exp Med1974https://conductscience.org/library/papers/4138849PubMed
29,026,476Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis.Gut1996https://conductscience.org/library/papers/9026476PubMed
31,104,747Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS.J Exp Med1975https://conductscience.org/library/papers/1104747PubMed
43,754,653Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.Science1986https://conductscience.org/library/papers/3754653PubMed
52,436,470Campylobacter pyloridis gastritis I: Detection of urease as a marker of bacterial colonization and gastritis.Am J Gastroenterol1987https://conductscience.org/library/papers/2436470PubMed
63,200,186The use of serology to diagnose active Campylobacter pylori infection.Med J Aust1988https://conductscience.org/library/papers/3200186PubMed
72,492,265Endotoxin-induced serum factor that stimulates gamma interferon production.Infect Immun1989https://conductscience.org/library/papers/2492265PubMed
82,759,091Structural characterization of the lipid A component of Bacteroides fragilis strain NCTC 9343 lipopolysaccharide.Eur J Biochem1989https://conductscience.org/library/papers/2759091PubMed
91,847,939Soluble surface proteins from Helicobacter pylori activate monocytes/macrophages by lipopolysaccharide-independent mechanism.J Clin Invest1991https://conductscience.org/library/papers/1847939PubMed
108,499,895Immunological activity of lipopolysaccharide of Helicobacter pylori on human peripheral mononuclear blood cells in comparison to lipopolysaccharides of other intestinal bacteria.FEMS Immunol Med Microbiol1993https://conductscience.org/library/papers/8499895PubMed
117,890,370Activation of human THP-1 cells and rat bone marrow-derived macrophages by Helicobacter pylori lipopolysaccharide.Infect Immun1995https://conductscience.org/library/papers/7890370PubMed
127,729,896Endotoxin-induced desensitization of mouse macrophages is mediated in part by nitric oxide production.Infect Immun1995https://conductscience.org/library/papers/7729896PubMed
137,612,223Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity.Annu Rev Immunol1995https://conductscience.org/library/papers/7612223PubMed
147,591,106Helicobacter pylori expresses a complex surface carbohydrate, Lewis X.Infect Immun1995https://conductscience.org/library/papers/7591106PubMed
157,473,824Helicobacter pylori and gastric atrophy--cancer paradoxes.J Natl Cancer Inst1995https://conductscience.org/library/papers/7473824PubMed
168,557,346Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection of inbred and congenic mouse strains.Infect Immun1996https://conductscience.org/library/papers/8557346PubMed
178,563,048Histological responses to Helicobacter pylori infection: gastritis, atrophy and preneoplasia.Baillieres Clin Gastroenterol1995https://conductscience.org/library/papers/8563048PubMed
188,652,594Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide regions.Biochemistry1996https://conductscience.org/library/papers/8652594PubMed
198,648,119Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice.J Immunol1996https://conductscience.org/library/papers/8648119PubMed
208,675,304Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity.Infect Immun1996https://conductscience.org/library/papers/8675304PubMed

See all 22 references

Cited by21

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 62 citations.

PMIDTitleJournalYearIn PapersSource
42,254,085Pernicious Anemia and Helicobacter pylori Infection: What a Hematologist Needs to Know?Clin Case Rep2026https://conductscience.org/library/papers/42254085PubMed
26,075,271Extraction optimization for obtaining Artemisia capillaris extract with high anti-inflammatory activity in RAW 264.7 macrophage cells.Biomed Res Int2015https://conductscience.org/library/papers/26075271PubMed
25,729,277The Effect of Polyphenols Isolated from Cynanchi wilfordii Radix with Anti-inflammatory, Antioxidant, and Anti-bacterial Activity.Korean J Physiol Pharmacol2015https://conductscience.org/library/papers/25729277PubMed
24,278,504Methanolic Extract of Asterina pectinifera inhibits LPS-Induced Inflammatory Mediators in Murine Macrophage.Toxicol Res2010https://conductscience.org/library/papers/24278504PubMed
23,956,624The Anti-inflammatory Effects of Water Extract from Cordyceps militaris in Murine Macrophage.Mycobiology2010https://conductscience.org/library/papers/23956624PubMed
21,850,571In silico quest for putative drug targets in Helicobacter pylori HPAG1: molecular modeling of candidate enzymes from lipopolysaccharide biosynthesis pathway.J Mol Model2012https://conductscience.org/library/papers/21850571PubMed
18,437,214Absence of Common Polymorphisms of Toll Like Receptor 4 (TLR4): Asp299Gly, Thr399Ile in Patients with Gastroduodenal Diseases in Japan.J Clin Biochem Nutr2007https://conductscience.org/library/papers/18437214PubMed
17,683,897Effects of a Th1- versus a Th2-biased immune response in protection against Helicobacter pylori challenge in mice.Microb Pathog2008https://conductscience.org/library/papers/17683897PubMed
17,353,291Deficiencies of myeloid differentiation factor 88, Toll-like receptor 2 (TLR2), or TLR4 produce specific defects in macrophage cytokine secretion induced by Helicobacter pylori.Infect Immun2007https://conductscience.org/library/papers/17353291PubMed
16,714,584CD4+ CD25+ regulatory T cells modulate the T-cell and antibody responses in helicobacter-infected BALB/c mice.Infect Immun2006https://conductscience.org/library/papers/16714584PubMed
16,030,209Identification of a D-glycero-D-manno-heptosyltransferase gene from Helicobacter pylori.J Bacteriol2005https://conductscience.org/library/papers/16030209PubMed
15,731,083Colonization and inflammation deficiencies in Mongolian gerbils infected by Helicobacter pylori chemotaxis mutants.Infect Immun2005https://conductscience.org/library/papers/15731083PubMed
15,501,775Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4.Infect Immun2004https://conductscience.org/library/papers/15501775PubMed
15,237,433Helicobacter pylori lipopolysaccharide: biological activities in vitro and in vivo, pathological correlation to human chronic gastritis and peptic ulcer.World J Gastroenterol2004https://conductscience.org/library/papers/15237433PubMed
14,500,487Helicobacter pylori outer membrane vesicles modulate proliferation and interleukin-8 production by gastric epithelial cells.Infect Immun2003https://conductscience.org/library/papers/14500487PubMed
12,540,559Colonization of C57BL/6J and BALB/c wild-type and knockout mice with Helicobacter pylori: effect of vaccination and implications for innate and acquired immunity.Infect Immun2003https://conductscience.org/library/papers/12540559PubMed
11,777,849Host cell responses to genotypically similar Helicobacter pylori isolates from United States and Japan.Clin Diagn Lab Immunol2002https://conductscience.org/library/papers/11777849PubMed
11,148,003Emergence of diverse Helicobacter species in the pathogenesis of gastric and enterohepatic diseases.Clin Microbiol Rev2001https://conductscience.org/library/papers/11148003PubMed
10,446,099A genetic basis for atrophy: dominant non-responsiveness and helicobacter induced gastritis in F(1) hybrid mice.Gut1999https://conductscience.org/library/papers/10446099PubMed
9,784,544Helicobacter pylori lipopolysaccharide binds to CD14 and stimulates release of interleukin-8, epithelial neutrophil-activating peptide 78, and monocyte chemotactic protein 1 by human monocytes.Infect Immun1998https://conductscience.org/library/papers/9784544PubMed

See all 21 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
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  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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