Paper1104747
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS.
Skidmore BJ and 3 others. J Exp Med, 1975. Cited by 144 papers, by iCite.
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ConductScience Library. Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. Papers, record 1104747. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1104747
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS.
- PubMed
- Publication types
- Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Lipopolysaccharides | Major topic |
| Lymphocytes | Major topic |
| Polysaccharides, Bacterial | Major topic |
| Spleen | Major topic |
| Animals | |
| DNA | |
| Escherichia coli | |
| Male | |
| Mice | |
| Mice, Inbred Strains | |
| Mitogens | |
| Species Specificity |
Source PubMed
References39
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,096,290 | Genetic control of B-cell responses. I. Selective unresponsiveness to lipopolysaccharide. | Scand J Immunol | 1975 | https://conductscience.org/library/papers/1096290 | PubMed |
| 2 | 1,095,471 | Relation of structure to function in bacterial O-antigens--VII. Endotoxicity of 'lipid A'. | Immunochemistry | 1975 | https://conductscience.org/library/papers/1095471 | PubMed |
| 3 | 5,227,701 | Structural relationship of Salmonella O and R antigens. | Ann N Y Acad Sci | 1966 | https://conductscience.org/library/papers/5227701 | PubMed |
| 4 | 5,804,498 | A new method for the extraction of R lipopolysaccharides. | Eur J Biochem | 1969 | https://conductscience.org/library/papers/5804498 | PubMed |
| 5 | 6,034,749 | Immunization of dissociated spleen cell cultures from normal mice. | J Exp Med | 1967 | https://conductscience.org/library/papers/6034749 | PubMed |
| 6 | 5,926,455 | Cytodynamics of the distinctive immune response produced in regional lymph nodes by Salmonella somatic polysaccharide. | J Immunol | 1966 | https://conductscience.org/library/papers/5926455 | PubMed |
| 7 | 16,557,702 | Specific inhibition of endotoxin coating of red cells by a human erythrocyte membrane component. | Infect Immun | 1970 | https://conductscience.org/library/papers/16557702 | PubMed |
| 9 | 14,299,610 | THE BIOSYNTHESIS OF CELL WALL LIPOPOLYSACCHARIDE IN ESCHERICHIA COLI. I. THE BIOCHEMICAL PROPERTIES OF A URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASELESS MUTANT. | J Biol Chem | 1965 | https://conductscience.org/library/papers/14299610 | PubMed |
| 12 | 14,069,871 | REDUCTION OF PSEUDOMONAS AERUGINOSA AND COLIFORM BACTERIA IN MOUSE DRINKING WATER FOLLOWING TREATMENT WITH HYDROCHLORIC ACID OR CHLORINE. | Lab Anim Care | 1963 | https://conductscience.org/library/papers/14069871 | PubMed |
| 13 | 13,813,473 | Estimation of 3-deoxy sugars by means of the malonaldehyde-thiobarbituric acid reaction. | Nature | 1960 | https://conductscience.org/library/papers/13813473 | PubMed |
| 14 | 13,672,993 | A sensitive colorimetric method for the estimation of 2-deoxy sugars with the use of the malonaldehyde-thiobarbituric acid reaction. | J Biol Chem | 1959 | https://conductscience.org/library/papers/13672993 | PubMed |
| 16 | 4,877,918 | Genetic control of leucocyte responses to endotoxin. | Nature | 1968 | https://conductscience.org/library/papers/4877918 | PubMed |
| 17 | 4,539,345 | PPD tuberculin--a B-cell mitogen. | Nat New Biol | 1972 | https://conductscience.org/library/papers/4539345 | PubMed |
| 18 | 4,138,849 | Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides. | J Exp Med | 1974 | https://conductscience.org/library/papers/4138849 | PubMed |
| 19 | 804,483 | Fractions of lipopolysaccharide from Escherichia coli O111:B4 prepared by two extraction procedures. | J Biol Chem | 1975 | https://conductscience.org/library/papers/804483 | PubMed |
| 20 | 4,204,442 | Degradative effect of phenol on endotoxin and lipopolysaccharide preparations from Serratia marcescens. | J Bacteriol | 1974 | https://conductscience.org/library/papers/4204442 | PubMed |
| 21 | 4,609,774 | Selective triggering of B cell subpopulations by mitogens. | Eur J Immunol | 1974 | https://conductscience.org/library/papers/4609774 | PubMed |
| 22 | 4,604,327 | Differentiation of B cells: sequential appearance of responsiveness to polyclonal activators. | Scand J Immunol | 1974 | https://conductscience.org/library/papers/4604327 | PubMed |
| 23 | 4,602,658 | Polyanions and lipopolysaccharide acts on different subpopulations of B cells. | Nature | 1974 | https://conductscience.org/library/papers/4602658 | PubMed |
| 24 | 4,577,879 | Mitogenicity of bacterial endotoxins: characterization of the mitogenic principle. | J Immunol | 1973 | https://conductscience.org/library/papers/4577879 | PubMed |
Cited by37
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 144 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 15,932,502 | Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells. | Clin Exp Immunol | 2005 | https://conductscience.org/library/papers/15932502 | PubMed |
| 15,147,344 | Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic colitis through the down-regulation of interleukin-6 production on colonic epithelial cells. | Clin Exp Immunol | 2004 | https://conductscience.org/library/papers/15147344 | PubMed |
| 10,446,099 | A genetic basis for atrophy: dominant non-responsiveness and helicobacter induced gastritis in F(1) hybrid mice. | Gut | 1999 | https://conductscience.org/library/papers/10446099 | PubMed |
| 10,084,984 | Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin. | Infect Immun | 1999 | https://conductscience.org/library/papers/10084984 | PubMed |
| 9,234,792 | The endotoxin of Helicobacter pylori is a modulator of host-dependent gastritis. | Infect Immun | 1997 | https://conductscience.org/library/papers/9234792 | PubMed |
| 8,801,436 | Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. | Microbiol Rev | 1996 | https://conductscience.org/library/papers/8801436 | PubMed |
| 7,655,992 | Modulins: a new class of cytokine-inducing, pro-inflammatory bacterial virulence factor. | Inflamm Res | 1995 | https://conductscience.org/library/papers/7655992 | PubMed |
| 7,014,458 | Role of antigen form in development of mucosal immunoglobin A response to Shigella flexneri Antigens. | Infect Immun | 1981 | https://conductscience.org/library/papers/7014458 | PubMed |
| 6,981,588 | Immunostimulating polysaccharide separated from hot water extract of Angelica acutiloba Kitagawa (Yamato tohki). | Immunology | 1982 | https://conductscience.org/library/papers/6981588 | PubMed |
| 6,785,242 | Evidence for the presence of lipopolysaccharide in a ribonuclease-sensitive ribosomal vaccine of Pseudomonas aeruginosa. | Infect Immun | 1981 | https://conductscience.org/library/papers/6785242 | PubMed |
| 6,358,257 | Enhanced survival in Pseudomonas aeruginosa septicemia associated with high levels of circulating antibody to Escherichia coli endotoxin core. | J Clin Invest | 1983 | https://conductscience.org/library/papers/6358257 | PubMed |
| 3,862,286 | Changes in membrane gangliosides: differentiation of human and murine monocytic cells. | Yale J Biol Med | 1985 | https://conductscience.org/library/papers/3862286 | PubMed |
| 3,286,501 | Endotoxin-associated protein: interleukin-1-like activity on serum amyloid A synthesis and T-lymphocyte activation. | Infect Immun | 1988 | https://conductscience.org/library/papers/3286501 | PubMed |
| 2,836,311 | Endotoxin-associated protein: a potent stimulus for human granulocytopoietic activity which may be accessory cell independent. | Infect Immun | 1988 | https://conductscience.org/library/papers/2836311 | PubMed |
| 1,937,834 | Interleukin-1 administration to C3H/HeJ mice after but not prior to infection increases resistance to Salmonella typhimurium. | Infect Immun | 1991 | https://conductscience.org/library/papers/1937834 | PubMed |
| 1,085,749 | Genetic analysis of lymphocyte activation by lipopolysaccharide Endotoxin. | Infect Immun | 1976 | https://conductscience.org/library/papers/1085749 | PubMed |
| 978,136 | Murine model for human secondary amyloidosis: genetic variability of the acute-phase serum protein SAA response to endotoxins and casein. | J Exp Med | 1976 | https://conductscience.org/library/papers/978136 | PubMed |
| 863,513 | Immunological responses of mice to lipopolysaccharide: lack of secondary responsiveness by C3H/HeJ mice. | Infect Immun | 1977 | https://conductscience.org/library/papers/863513 | PubMed |
| 702,060 | Suppression of the immune response in C3H/HeJ mice by protein-free lipopolysaccharides. | J Exp Med | 1978 | https://conductscience.org/library/papers/702060 | PubMed |
| 689,731 | Distribution of endotoxin (lipopolysaccharide) in the tissues of lipopolysaccharide-responsive and -unresponsive mice. | Infect Immun | 1978 | https://conductscience.org/library/papers/689731 | PubMed |
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- 2026-09-18
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- ClinicalTrials.govNo license stated
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- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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