Paper92520
T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes.
Solinger AM and 3 others. J Exp Med, 1979. Cited by 213 papers, by iCite.
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ConductScience Library. T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes. Papers, record 92520. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/92520
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes.
- PubMed
Topics18
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Cytochrome c Group | Major topic |
| Epitopes | Major topic |
| Genetic Linkage | Major topic |
| Major Histocompatibility Complex | Major topic |
| T-Lymphocytes | Major topic |
| Animals | |
| Ascitic Fluid | |
| Cell Division | |
| Chromosome Mapping | |
| Columbidae | |
| Female | |
| Genes | |
| H-2 Antigens | |
| Humans | |
| Male | |
| Mice | |
| Protein Conformation | |
| Species Specificity |
Source PubMed
References30
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 100,572 | Two-gene control of the expression of a murine Ia antigen. | J Exp Med | 1978 | https://conductscience.org/library/papers/100572 | PubMed |
| 2 | 105,077 | Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell. | J Exp Med | 1979 | https://conductscience.org/library/papers/105077 | PubMed |
| 3 | 1,059,157 | Complementation of H-2-linked Ir genes in the mouse. | Proc Natl Acad Sci U S A | 1975 | https://conductscience.org/library/papers/1059157 | PubMed |
| 4 | 1,082,491 | T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation. | J Exp Med | 1976 | https://conductscience.org/library/papers/1082491 | PubMed |
| 5 | 1,082,919 | The requirement for two complementing Ir-GLphi immune response genes in the T-lymphocyte proliferative response to poly-(Glu53Lys36Phe11). | J Exp Med | 1976 | https://conductscience.org/library/papers/1082919 | PubMed |
| 6 | 109,567 | Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. I. Genetic control of delayed-type hypersensitivity by VH and I-A-region genes. | J Exp Med | 1979 | https://conductscience.org/library/papers/109567 | PubMed |
| 7 | 13,640,681 | Studies on hypersensitivity. II. Delayed hypersensitivity to denatured proteins in guinea pigs. | Immunology | 1959 | https://conductscience.org/library/papers/13640681 | PubMed |
| 8 | 165,078 | Conformational studies of equilibrium structures in fragments of horse heart cytochrome c. | Eur J Biochem | 1975 | https://conductscience.org/library/papers/165078 | PubMed |
| 9 | 166,072 | The crystal structure of bonito (katsuo) ferrocytochrome c at 2.3 A resolution. II. Structure and function. | J Biochem | 1975 | https://conductscience.org/library/papers/166072 | PubMed |
| 10 | 194,885 | Tuna cytochrome c at 2.0 A resolution. III. Coordinate optimization and comparison of structures. | J Biol Chem | 1977 | https://conductscience.org/library/papers/194885 | PubMed |
| 11 | 213,675 | Mitochondrial cytochrome c: preparation and activity of native and chemically modified cytochromes c. | Methods Enzymol | 1978 | https://conductscience.org/library/papers/213675 | PubMed |
| 12 | 281,690 | Interactive computer surface graphics approach to study of the active site of bovine trypsin. | Proc Natl Acad Sci U S A | 1978 | https://conductscience.org/library/papers/281690 | PubMed |
| 13 | 307,022 | Genetic control of the T lymphocyte proliferative response to staphylococcal nuclease: evidence for multiple MHC-linked Ir gene control. | J Immunol | 1978 | https://conductscience.org/library/papers/307022 | PubMed |
| 14 | 4,138,630 | Immune responses against native and chemically modified albumins in mice. II. Effect of electric charge and conformation on the humoral antibody response and on helper T cell responses. | J Immunol | 1974 | https://conductscience.org/library/papers/4138630 | PubMed |
| 15 | 418,137 | Isolated hapten-binding receptors of sensitized lymphocytes. III. Evidence for idiotypic restriction of T-cell receptors. | J Exp Med | 1978 | https://conductscience.org/library/papers/418137 | PubMed |
| 16 | 4,586,168 | Strain differences in the fine specificity of mouse anti-hapten antibodies. | Eur J Immunol | 1973 | https://conductscience.org/library/papers/4586168 | PubMed |
| 17 | 4,949,245 | The molecular variations of cytochrome c as a function of the evolution of species. | Harvey Lect | 1971 | https://conductscience.org/library/papers/4949245 | PubMed |
| 18 | 54,223 | Reaginic antibody formation in the mouse. VI. Suppression of IgE and IgG antibody responses to ovalbumin following the administration of high dose urea-denatured antigen. | Cell Immunol | 1975 | https://conductscience.org/library/papers/54223 | PubMed |
| 19 | 5,499,432 | Cleavage of cytochrome c with cyanogen bromide. | Biochim Biophys Acta | 1970 | https://conductscience.org/library/papers/5499432 | PubMed |
| 20 | 5,839,284 | Genetic control of the antibody response. I. Demonstration of determinant-specific differences in response to synthetic polypeptide antigens in two strains of inbred mice. | J Exp Med | 1965 | https://conductscience.org/library/papers/5839284 | PubMed |
Cited by57
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 213 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 34,855,510 | Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants. | Science | 2022 | https://conductscience.org/library/papers/34855510 | PubMed |
| 28,893,274 | Modulation of the strength and character of HIV-specific CD8+ T cell responses with heteroclitic peptides. | AIDS Res Ther | 2017 | https://conductscience.org/library/papers/28893274 | PubMed |
| 27,376,549 | Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. | Elife | 2016 | https://conductscience.org/library/papers/27376549 | PubMed |
| 26,257,743 | Enhancing Human Immunodeficiency Virus-Specific CD8(+) T Cell Responses with Heteroclitic Peptides. | Front Immunol | 2015 | https://conductscience.org/library/papers/26257743 | PubMed |
| 25,576,665 | Determinants of immunodominance for CD4 T cells. | Curr Opin Immunol | 2015 | https://conductscience.org/library/papers/25576665 | PubMed |
| 25,086,170 | Antigen signal strength during priming determines effector CD4 T cell function and antigen sensitivity during influenza virus challenge. | J Immunol | 2014 | https://conductscience.org/library/papers/25086170 | PubMed |
| 24,424,413 | T cell immunodominance is dictated by the positively selecting self-peptide. | Elife | 2014 | https://conductscience.org/library/papers/24424413 | PubMed |
| 23,237,510 | Cross-reactivity of T cells and its role in the immune system. | Crit Rev Immunol | 2012 | https://conductscience.org/library/papers/23237510 | PubMed |
| 21,490,152 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k). | J Immunol | 2011 | https://conductscience.org/library/papers/21490152 | PubMed |
| 20,331,477 | Regulation of CD4 T-cell receptor diversity by vaccine adjuvants. | Immunology | 2010 | https://conductscience.org/library/papers/20331477 | PubMed |
| 20,007,533 | Peptide-MHC class II complex stability governs CD4 T cell clonal selection. | J Immunol | 2010 | https://conductscience.org/library/papers/20007533 | PubMed |
| 19,562,081 | Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients. | PLoS One | 2009 | https://conductscience.org/library/papers/19562081 | PubMed |
| 19,037,317 | The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease. | Nature | 2008 | https://conductscience.org/library/papers/19037317 | PubMed |
| 17,936,255 | Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains. | Cell Immunol | 2007 | https://conductscience.org/library/papers/17936255 | PubMed |
| 17,804,011 | Hock immunization: a humane alternative to mouse footpad injections. | J Immunol Methods | 2007 | https://conductscience.org/library/papers/17804011 | PubMed |
| 15,578,104 | Using modified antigenic sequences to develop cancer vaccines: are we losing the focus? | PLoS Med | 2004 | https://conductscience.org/library/papers/15578104 | PubMed |
| 11,956,295 | Structural basis of cytochrome c presentation by IE(k). | J Exp Med | 2002 | https://conductscience.org/library/papers/11956295 | PubMed |
| 9,802,967 | Heteroclitic immunization induces tumor immunity. | J Exp Med | 1998 | https://conductscience.org/library/papers/9802967 | PubMed |
| 7,534,228 | Predicted complementarity determining regions of the T cell antigen receptor determine antigen specificity. | EMBO J | 1995 | https://conductscience.org/library/papers/7534228 | PubMed |
| 6,980,183 | Inhibition by Fab and Fab'2 monoclonal anti-Ia antibody fragments of T-lymphocyte proliferative responses. | Immunology | 1982 | https://conductscience.org/library/papers/6980183 | PubMed |
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- 2026-09-18
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- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- HGNCCC0: https://www.genenames.org/about/license/
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- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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