Paper931997
Protein degradation in human fibroblasts (WI-38). Effects of aging, viral transformation, and amino acid analogs.
Bradley MO and 2 others. J Biol Chem, 1976. Cited by 113 papers, by iCite.
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ConductScience Library. Protein degradation in human fibroblasts (WI-38). Effects of aging, viral transformation, and amino acid analogs. Papers, record 931997. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/931997
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Protein degradation in human fibroblasts (WI-38). Effects of aging, viral transformation, and amino acid analogs.
- PubMed
Topics13
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Aging | Major topic |
| Amino Acids | Major topic |
| Cell Transformation, Neoplastic | Major topic |
| Proteins | Major topic |
| Biological Transport | |
| Cell Division | |
| Cell Line | |
| Cell Survival | |
| Kinetics | |
| Leucine | |
| Mathematics | |
| Protein Biosynthesis | |
| Time Factors |
Source PubMed
Cited by17
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 113 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 26,961,882 | Rapidly Translated Polypeptides Are Preferred Substrates for Cotranslational Protein Degradation. | J Biol Chem | 2016 | https://conductscience.org/library/papers/26961882 | PubMed |
| 25,709,559 | The proteome profiles of the olfactory bulb of juvenile, adult and aged rats - an ontogenetic study. | Proteome Sci | 2015 | https://conductscience.org/library/papers/25709559 | PubMed |
| 7,305,898 | Protein degradation in skin fibroblasts from patients with Duchenne muscular dystrophy. | Biochem J | 1980 | https://conductscience.org/library/papers/7305898 | PubMed |
| 7,153,243 | Clonal selection in cultured human fibroblasts: role of protein synthetic errors. | J Cell Biol | 1982 | https://conductscience.org/library/papers/7153243 | PubMed |
| 7,028,761 | Degradation of proteins microinjected into IMR-90 human diploid fibroblasts. | J Cell Biol | 1981 | https://conductscience.org/library/papers/7028761 | PubMed |
| 6,756,389 | Protein turnover and proliferation. Turnover kinetics associated with the elevation of 3T3-cell acid-proteinase activity and cessation of net protein gain. | Biochem J | 1982 | https://conductscience.org/library/papers/6756389 | PubMed |
| 6,387,441 | Genetic modifications during cellular aging. | Mol Cell Biochem | 1984 | https://conductscience.org/library/papers/6387441 | PubMed |
| 6,323,303 | Amino acid analogs inhibit murine xenotropic retrovirus expression and cell cycle progression. | In Vitro | 1984 | https://conductscience.org/library/papers/6323303 | PubMed |
| 6,086,007 | Dual pathways for ribonucleic acid turnover in WI-38 but not in I-cell human diploid fibroblasts. | Mol Cell Biol | 1981 | https://conductscience.org/library/papers/6086007 | PubMed |
| 3,455,753 | L-Canavanine and protein synthesis in the tobacco hornworm Manduca sexta. | Proc Natl Acad Sci U S A | 1986 | https://conductscience.org/library/papers/3455753 | PubMed |
| 3,226,468 | Changes of mitochondrial membrane proteins in rat cerebellum during aging. | Neurochem Res | 1988 | https://conductscience.org/library/papers/3226468 | PubMed |
| 2,930,516 | Vanadate inhibits degradation of short-lived, but not of long-lived, proteins in L-132 human cells. | Biochem J | 1989 | https://conductscience.org/library/papers/2930516 | PubMed |
| 2,509,484 | A homologue of the axonally secreted protein axonin-1 is an integral membrane protein of nerve fiber tracts involved in neurite fasciculation. | J Cell Biol | 1989 | https://conductscience.org/library/papers/2509484 | PubMed |
| 1,944,772 | Effect of hypoxia on mitochondrial protein composition of cerebral cortex during aging. | Neurochem Res | 1991 | https://conductscience.org/library/papers/1944772 | PubMed |
| 880,243 | Effect of a nutritional shift on the degradation of abnormal proteins in the mouse liver. Decreased degradation during rapid liver growth. | Biochem J | 1977 | https://conductscience.org/library/papers/880243 | PubMed |
| 597,269 | Effect of microtubular or translational inhibitors on general cell protein degradation. Evidence for a dual catabolic pathway. | Biochem J | 1977 | https://conductscience.org/library/papers/597269 | PubMed |
| 264,694 | A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes. | Proc Natl Acad Sci U S A | 1977 | https://conductscience.org/library/papers/264694 | PubMed |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
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- Trials
- Comments and corrections
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- Genes
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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