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Paper · 978583

A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.

Ritchie JM and 2 others. J Physiol, 1976. Cited by 190 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves. Papers, record 978583. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/978583

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.
PubMed
Journal
J Physiol
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
190
iCite
Relative citation ratio, by iCite
6.64
iCite
Revised in PubMed
2019-05-09
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Ritchie JMJ M
2Rogart RBR B
3Strichartz GRG R

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Isotope LabelingMajor topic
Nerve FibersMajor topic
SaxitoxinMajor topic
Animals
Binding Sites
Fishes
Muscles
Nephropidae
Olfactory Nerve
Rabbits
Sodium
Tritium
Vagus Nerve

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References19

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1238,232The purity of tritiated tetrodotoxin as determined by bioassay.Philos Trans R Soc Lond B Biol Sci1975https://conductscience.org/library/papers/238232PubMed
2238,231Binding of tetrodotoxin and saxitoxin to sodium channels.Philos Trans R Soc Lond B Biol Sci1975https://conductscience.org/library/papers/238231PubMed
31,083,895Density and distribution of tetrodotoxin receptors in normal and detubulated frog sartorius muscle.J Gen Physiol1976https://conductscience.org/library/papers/1083895PubMed
44,530,274Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4530274PubMed
55,038,273Binding of radioactive tetrodotoxin to nerve membrane preparations.Biochim Biophys Acta1972https://conductscience.org/library/papers/5038273PubMed
61,133,383Letter: The structure of saxitoxin.J Am Chem Soc1975https://conductscience.org/library/papers/1133383PubMed
75,573,568Garfish olfactory nerve: easily accessible source of numerous long, homogeneous, nonmyelinated axons.Science1971https://conductscience.org/library/papers/5573568PubMed
813,642,309Movements of Na and K in single muscle fibres.J Physiol1959https://conductscience.org/library/papers/13642309PubMed
94,646,588The binding of labelled tetrodotoxin to non-myelinated nerve fibres.J Physiol1972https://conductscience.org/library/papers/4646588PubMed
105,016,360The interaction at equilibrium between tetrodotoxin and mammalian non-myelinated nerve fibres.J Physiol1972https://conductscience.org/library/papers/5016360PubMed

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Cited by32

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 190 citations.

PMIDTitleJournalYearIn PapersSource
35,315,190Chemical and Biological Tools for the Study of Voltage-Gated Sodium Channels in Electrogenesis and Nociception.Chembiochem2022https://conductscience.org/library/papers/35315190PubMed
26,432,640Finding Channels.J Biol Chem2015https://conductscience.org/library/papers/26432640PubMed
20,033,248The dependence of auditory nerve rate adaptation on electric stimulus parameters, electrode position, and fiber diameter: a computer model study.J Assoc Res Otolaryngol2010https://conductscience.org/library/papers/20033248PubMed
18,941,294Tetrodotoxin: a brief history.Proc Jpn Acad Ser B Phys Biol Sci2008https://conductscience.org/library/papers/18941294PubMed
7,279,111Composition of axolemma-enriched fractions isolated from bovine CNS myelinated axons.Neurochem Res1981https://conductscience.org/library/papers/7279111PubMed
6,325,471Components of the plasma membrane of growing axons. III. Saxitoxin binding to sodium channels.J Cell Biol1984https://conductscience.org/library/papers/6325471PubMed
6,320,167Electrical activity and cytosolic calcium regulate levels of tetrodotoxin-sensitive sodium channels in cultured rat muscle cells.Proc Natl Acad Sci U S A1984https://conductscience.org/library/papers/6320167PubMed
6,302,670Identification of two sodium channel subtypes in chick heart and brain.Proc Natl Acad Sci U S A1983https://conductscience.org/library/papers/6302670PubMed
6,284,939Sodium currents in the giant axon of the crab Carcinus maenas.J Membr Biol1982https://conductscience.org/library/papers/6284939PubMed
6,280,195Isolation and characterization of a monoclonal antibody against the saxitoxin-binding component from the electric organ of the eel Electrophorus electricus.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6280195PubMed

1 to 10 of 32

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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