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Trial · NCT00486434

Results by group107

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Joint Space Width (JSW) in the Medial Tibiofemoral Knee Joint in Signal Knee Measured by X-ray After 24 Months.Active Arm-0.188Standard Deviation 0.5626mm
Joint Space Width (JSW) in the Medial Tibiofemoral Knee Joint in Signal Knee Measured by X-ray After 24 Months.Placebo Arm-0.198Standard Deviation 0.5069mm
Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Subscore in the Signal KneeActive Arm-124.0Inter-Quartile Range -391 to 218Units on a scale
Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Subscore in the Signal KneePlacebo Arm-109.0Inter-Quartile Range -410 to 349Units on a scale
Western Ontario and McMaster Universities Arthritis Index (WOMAC) Function Subscore in the Signal Knee.Active Arm-390.0Inter-Quartile Range -1307 to 783Units on a scale
Western Ontario and McMaster Universities Arthritis Index (WOMAC) Function Subscore in the Signal Knee.Placebo Arm-299.5Inter-Quartile Range -1342 to 915Units on a scale
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Active ArmSerum CTX-I (ng/mL)41.358Standard Deviation 68.1153percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Placebo ArmSerum CTX-I (ng/mL)62.883Standard Deviation 65.7225percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Active ArmSerum Osteocalcin (ng/mL)-9.134Standard Deviation 22.1368percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Placebo ArmSerum Osteocalcin (ng/mL)1.785Standard Deviation 22.8324percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Active Arm24-h urine CTX-I/creatinine (µg/mmol)-8.959Standard Deviation 50.0723percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Placebo Arm24-h urine CTX-I/creatinine (µg/mmol)8.311Standard Deviation 55.4934percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Active Arm24-h urine CTX-II/creatinine (ng/mmol)0.484Standard Deviation 56.4879percentage of change
Changes in Biochemical Markers of Bone & Cartilage Metabolism.Placebo Arm24-h urine CTX-II/creatinine (ng/mmol)11.266Standard Deviation 49.6250percentage of change
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsActive ArmTotal osteophytes0.40Standard Deviation 0.784Scores on a scale
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsPlacebo ArmTotal osteophytes0.40Standard Deviation 0.754Scores on a scale
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsActive ArmTotal JSN0.45Standard Deviation 1.063Scores on a scale
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsPlacebo ArmTotal JSN0.62Standard Deviation 0.990Scores on a scale
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsActive ArmTotal cyst/erosions0.83Standard Deviation 1.204Scores on a scale
Effect on Hand Osteoarthritis (OA) Assessed by X-ray & Questionnaire From Baseline to 24 MonthsPlacebo ArmTotal cyst/erosions0.82Standard Deviation 1.327Scores on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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