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Trial · NCT00624468

Results by group90

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Last Observed Value (LOV)Placebo: Double-blind PeriodBaseline (n = 17, 17)103.893Standard Deviation 17.271micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Last Observed Value (LOV)Atacicept: Double-blind PeriodBaseline (n = 17, 17)104.170Standard Deviation 8.832micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Last Observed Value (LOV)Placebo: Double-blind PeriodChange at LOV (n = 16, 15)-17.317Standard Deviation 15.158micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Last Observed Value (LOV)Atacicept: Double-blind PeriodChange at LOV (n = 16, 15)-8.636Standard Deviation 10.056micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyePlacebo: Double-blind PeriodChange at Week 12 (n = 13, 13)-14Standard Error 4micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyeAtacicept: Double-blind PeriodChange at Week 12 (n = 13, 13)-7.9Standard Error 1.5micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyePlacebo: Double-blind PeriodChange at Week 24 (n = 4, 5)-7Standard Error 6.9micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyeAtacicept: Double-blind PeriodChange at Week 24 (n = 4, 5)-10.6Standard Error 3.7micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyePlacebo: Double-blind PeriodChange at Week 36 (n = 3, 4)-7.5Standard Error 8.8micrometer
Difference in Retinal Nerve Fibre Layer (RNFL) Thickness Between the Affected Eye and Fellow EyeAtacicept: Double-blind PeriodChange at Week 36 (n = 3, 4)-9.4Standard Error 6.6micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Placebo: Double-blind PeriodBaseline (n=17, 17)103.893Standard Deviation 17.271micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Atacicept: Double-blind PeriodBaseline (n=17, 17)104.170Standard Deviation 8.832micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Placebo: Double-blind PeriodChange at Week 12 (n = 13, 13)-17.036Standard Deviation 13.919micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Atacicept: Double-blind PeriodChange at Week 12 (n = 13, 13)-9.356Standard Deviation 9.532micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Placebo: Double-blind PeriodChange at Week 24 (n = 4, 5)-17.815Standard Deviation 16.505micrometer
Change From Baseline in Retinal Nerve Fiber Layer (RNFL) Thickness in the Affected Eye at Weeks 12 and 24Atacicept: Double-blind PeriodChange at Week 24 (n = 4, 5)-11.234Standard Deviation 14.230micrometer
Change From Baseline in Macular Thickness at 3 Millimeter (mm) Around Fovea in the Affected Eye at Weeks 12, 24 and 36Placebo: Double-blind PeriodBaseline (n = 17, 17)1054.4Standard Deviation 76.5micrometer
Change From Baseline in Macular Thickness at 3 Millimeter (mm) Around Fovea in the Affected Eye at Weeks 12, 24 and 36Atacicept: Double-blind PeriodBaseline (n = 17, 17)1070.6Standard Deviation 72.7micrometer
Change From Baseline in Macular Thickness at 3 Millimeter (mm) Around Fovea in the Affected Eye at Weeks 12, 24 and 36Placebo: Double-blind PeriodChange at Week 12 (n = 13, 13)-29.3Standard Deviation 34.4micrometer
Change From Baseline in Macular Thickness at 3 Millimeter (mm) Around Fovea in the Affected Eye at Weeks 12, 24 and 36Atacicept: Double-blind PeriodChange at Week 12 (n = 13, 13)-34.0Standard Deviation 21.8micrometer

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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