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Trial · NCT00683124

Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryBSA and age-adjusted aortic root diameter (sinuses of Valsalva)every 12 months
SecondaryThe pharmacokinetics of the two drugs by age and dosagesevery 12 months
SecondaryComparative evaluation of the serum levels of total and active TGFbevery 12 months
SecondaryQuantitative assessment of the expression of the mutated gene (FBN1, both 5' and 3')every 12 months
SecondaryPharmacogenetic bases of drug responsiveness (Losartan: CYP2C9 gene) (Nebivolol: CYP2D6 gene)every 12 months
SecondaryAortic valve regurgitation severityevery 12 months
SecondaryLeft ventricular end-diastolic diameterevery 12 months
SecondaryLeft ventricular ejection fractionevery 12 months
SecondarySpirometric lung volumes and flowsevery 12 months
SecondaryQoL evaluation basing on SF-36 questionnaireevery 12 months
SecondaryArterial stiffness (carotids)every 12 months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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GET https://conductscience.org/api/trials/v1/NCT00683124/registered