Trial · NCT01902290
Outcomes15
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
1 to 15 of 15
Download this page as JSON| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change From Baseline in Asthma Control Questionnaire (ACQ) Composite Score at Week 24 | Baseline and week 24 | Full analysis set with available data | score on a scale | LEAST_SQUARES_MEAN |
| SECONDARY | Asthma Exacerbation Rate | Baseline to week 24 | Full analysis set with available data | exacerbations per subject-year | NUMBER |
| SECONDARY | Change From Baseline in ACQ Composite Score at Week 24 in ICS+LABA Subpopulation | Baseline and week 24 | Full analysis set participants who were taking both inhaled corticosteroids (ICS) and a long-acting β-agonist (LABA) at baseline with available data. | score on a scale | LEAST_SQUARES_MEAN |
| SECONDARY | Asthma Exacerbation Rate in ICS+LABA Subpopulation | Baseline to week 24 | Full analysis set participants taking both ICS and LABA at baseline with available data | exacerbations per subject-year | NUMBER |
| SECONDARY | Change From Baseline in Daily Asthma Symptom Score (7-day Average Score) | Baseline and week 24 | Full analysis set with available data | score on a scale | LEAST_SQUARES_MEAN |
| SECONDARY | Change From Baseline in Pre-bronchodilator Forced Expiratory Volume in One Second (FEV1) | Baseline and week 24 | Full analysis set with available data | L/s | LEAST_SQUARES_MEAN |
| SECONDARY | Change From Baseline in Daily Rescue Short-acting Beta-agonist Use | Baseline and week 24 | Full analysis set with available data | puffs | LEAST_SQUARES_MEAN |
| SECONDARY | Time to First Asthma Exacerbation | From first dose of study drug to week 24 | Full analysis set with available data | percentage of participants | NUMBER |
| SECONDARY | Number of Participants Who Experienced an Asthma Exacerbation | Baseline to week 24 | Full analysis set with available data | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Change From Baseline in Asthma Quality of Life Questionnaire (AQLQ) Overall Score | Baseline and week 24 | Full analysis set with available data | score on a scale | LEAST_SQUARES_MEAN |
| SECONDARY | Change From Baseline in Morning and Evening Peak Expiratory Flow Rate (PEFR) | Baseline and week 24 | Full analysis set with available data | L/min | LEAST_SQUARES_MEAN |
| SECONDARY | Change From Baseline in Variation of Peak Flow | Baseline and week 24 | Full analysis set with available data | L/min | LEAST_SQUARES_MEAN |
| SECONDARY | Proportion of Asthma Symptom-free Days in 4-weeks Intervals Over the Treatment Period | Baseline (the 4 weeks prior to first dose) and 4-week intervals up to week 24 | Full analysis set with available data during each 4-week interval | proportion of days | MEAN |
| SECONDARY | Serum Brodalumab Concentration | Day 1 and weeks 1, 2, 4, 8, 12, 16, and 22 at predose, week 2 + 3 days, week 22 + 3, 7, 10, and 14 days | Participants who received brodalumab with available concentration data at each time point. | µg/mL | MEAN |
| OTHER_PRE_SPECIFIED | Number of Participants With Treatment-emergent Adverse Events (TEAEs) | From first dose of study drug up to the end of study, 28 weeks | Randomized participants who received at least 1 dose of study drug. | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT01902290/outcomes