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Trial · NCT02130557

Results by group71

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With Major Molecular Response (MMR) at Month 12Bosutinib47.295% Confidence Interval 40.9 to 53.4percentage of participants
Percentage of Participants With Major Molecular Response (MMR) at Month 12Imatinib36.995% Confidence Interval 30.8 to 43.0percentage of participants
Percentage of Participants With Major Molecular Response (MMR) Up to Month 18Bosutinib61.095% Confidence Interval 54.9 to 67.1percentage of participants
Percentage of Participants With Major Molecular Response (MMR) Up to Month 18Imatinib52.795% Confidence Interval 46.4 to 59.0percentage of participants
Kaplan-Meier Estimate of Probability of Retaining Major Molecular Response (MMR) at Month 48Bosutinib92.295% Confidence Interval 86.8 to 95.4percentage of participants
Kaplan-Meier Estimate of Probability of Retaining Major Molecular Response (MMR) at Month 48Imatinib92.095% Confidence Interval 85.9 to 95.5percentage of participants
Percentage of Participants With Complete Cytogenetic Response (CCyR) Up to Month 12Bosutinib77.295% Confidence Interval 72.0 to 82.5percentage of participants
Percentage of Participants With Complete Cytogenetic Response (CCyR) Up to Month 12Imatinib66.495% Confidence Interval 60.4 to 72.4percentage of participants
Kaplan-Meier Estimate of Probability of Retaining Complete Cytogenetic Response (CCyR) at Month 48Bosutinib97.495% Confidence Interval 93.9 to 98.9percentage of participants
Kaplan-Meier Estimate of Probability of Retaining Complete Cytogenetic Response (CCyR) at Month 48Imatinib93.795% Confidence Interval 88.9 to 96.5percentage of participants
Cumulative Incidence of Event Free Survival (EFS) EventsBosutinib6.995% Confidence Interval 4.2 to 10.5percentage of participants
Cumulative Incidence of Event Free Survival (EFS) EventsImatinib10.495% Confidence Interval 6.9 to 14.6percentage of participants
Overall Survival (OS) RateBosutinib94.995% Confidence Interval 91.1 to 97.0percentage of participants
Overall Survival (OS) RateImatinib94.095% Confidence Interval 90.1 to 96.4percentage of participants
Summary of Trough Plasma Concentration by Complete Cytogenetic Response (CCyR) of BosutinibBosutinibDay 2871.282Standard Deviation 46.0545nanogram per milliliter (ng/mL)
Summary of Trough Plasma Concentration by Complete Cytogenetic Response (CCyR) of BosutinibBosutinibDay 5673.069Standard Deviation 45.1349nanogram per milliliter (ng/mL)
Summary of Trough Plasma Concentration by Complete Cytogenetic Response (CCyR) of BosutinibBosutinibDay 8483.973Standard Deviation 64.3206nanogram per milliliter (ng/mL)
Summary of Trough Plasma Concentration by Major Molecular Response (MMR) of BosutinibBosutinibDay 2875.050Standard Deviation 51.9551ng/mL
Summary of Trough Plasma Concentration by Major Molecular Response (MMR) of BosutinibBosutinibDay 5678.437Standard Deviation 43.6019ng/mL
Summary of Trough Plasma Concentration by Major Molecular Response (MMR) of BosutinibBosutinibDay 8491.081Standard Deviation 72.1500ng/mL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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