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Trial · NCT02304367

Results by group301

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants Achieving Mean Serum Phosphorus Levels Above 2.5 mg/dL at the Mid-Point of the Dose Intervals Between Baseline and Week 24Burosumab50.095% Confidence Interval 26.80 to 73.20percentage of participants
Change From Baseline to Week 48 in Osteoid ThicknessBurosumab-5.1295% Confidence Interval -10.04 to -0.20µm
Change From Baseline to Week 48 in Osteoid Surface/Bone Surface (OS/BS)Burosumab-0.1895% Confidence Interval -13.86 to 13.50percentage of bone surface
Change From Baseline to Week 48 in Osteoid Volume/Bone Volume (OV/BV)Burosumab-5.4795% Confidence Interval -11.87 to 0.93percentage of bone volume
Change From Baseline to Week 48 in Mineralization Lag Time (MLt)Burosumab-565.2095% Confidence Interval -2037.42 to 907.02days
Percentage of Participants Achieving Mean Serum Phosphorus Levels Above 2.5 mg/dL at the End of the Dose Intervals Between Baseline and Week 24Burosumab21.495% Confidence Interval 7.57 to 47.59percentage of participants
Mean Change From Baseline in Serum Phosphorus Levels at the Mid-Point of the Dose Interval, as Averaged Across Dose Cycles Between Baseline and Week 24Burosumab1.039Standard Deviation 0.5622mg/dL
Percent Change From Baseline in Serum Phosphorus Levels at the Mid-Point of the Dose Interval, as Averaged Across Dose Cycles Between Baseline and Week 24Burosumab69.77Standard Deviation 43.743percent change
Mean Change From Baseline in Serum Phosphorus Levels at the End of the Dosing Cycle, as Averaged Across Dose Cycles Between Baseline and Week 24Burosumab0.550Standard Deviation 0.4260mg/dL
Percent Mean Change From Baseline in Serum Phosphorus Levels at the End of the Dosing Cycle, as Averaged Across Dose Cycles Between Baseline and Week 24Burosumab38.56Standard Deviation 33.027percent change
Time-Adjusted Area Under the Curve (AUC) of Serum Phosphorus Levels Between Baseline and Week 24Burosumab2.36Standard Deviation 0.632mg/dL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 249.90Standard Error 4.10pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 4810.49Standard Error 4.82pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 964.28Standard Error 3.80pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 1443.15Standard Error 3.34pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 1684.91Standard Error 3.94pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 1920.67Standard Error 4.19pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 2169.78Standard Error 3.04pg/mL
Change From Baseline Over Time in Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) ConcentrationBurosumabWeek 2406.56Standard Error 3.19pg/mL
Change From Baseline Over Time in Total Serum Fibroblast Growth Factor 23 (FGF23) ConcentrationBurosumabWeek 24246335.35Standard Error 61089.98pg/mL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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