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Topiramate for Cryptogenic Sensory Peripheral Neuropathy in Metabolic Syndrome (CSPN)
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Trial · NCT02878798

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

1 to 20 of 24

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OutcomeGroupCategoryValueSpreadUnits
Intraepidermal Nerve Fiber Density (IENFD)Placebo-0.606495% Confidence Interval -1.1785 to -0.03437fibers/mm/year (52 weeks)
Intraepidermal Nerve Fiber Density (IENFD)Topiramate-0.39695% Confidence Interval -0.9625 to 0.1705fibers/mm/year (52 weeks)
Norfolk Quality of Life - Diabetic NeuropathyPlacebo3.581595% Confidence Interval 1.3162 to 5.8467Change inTotal NQOL-DN score over 52 wks
Norfolk Quality of Life - Diabetic NeuropathyTopiramate2.059695% Confidence Interval -0.2545 to 4.3737Change inTotal NQOL-DN score over 52 wks
Brief Pain Inventory - Diabetic Neuropathy (BPI-DN) Pain InterferencePlacebo0.199995% Confidence Interval -0.3602 to 0.7600Slope of change in BPI-DN PI over 52 wks
Brief Pain Inventory - Diabetic Neuropathy (BPI-DN) Pain InterferenceTopiramate0.176795% Confidence Interval -0.3984 to 0.7517Slope of change in BPI-DN PI over 52 wks
Brief Pain Inventory - Diabetic Neuropathy (BPI-DN) Average Pain IntensityPlacebo-0.104695% Confidence Interval -0.3431 to 0.1338Slope of change in BPI-DN pain over 52 w
Brief Pain Inventory - Diabetic Neuropathy (BPI-DN) Average Pain IntensityTopiramate-0.272695% Confidence Interval -0.5176 to -0.0276Slope of change in BPI-DN pain over 52 w
Utah Early Neuropathy ScalePlacebo0.428195% Confidence Interval -0.2409 to 1.0970Slope of change in Total UENS over 52wks
Utah Early Neuropathy ScaleTopiramate0.367195% Confidence Interval -0.3220 to 1.0562Slope of change in Total UENS over 52wks
Sural Sensory Amplitude (SSA)Placebo0.033495% Confidence Interval -0.0320 to 0.0987slope of change in SSA uV over 52 wks
Sural Sensory Amplitude (SSA)Topiramate0.04495% Confidence Interval -0.0232 to 0.1111slope of change in SSA uV over 52 wks
Peroneal Motor Conduction Velocity (PMCV)Placebo-0.0436395% Confidence Interval -0.5073 to 0.4200Slope of change in M/S over 52 wks
Peroneal Motor Conduction Velocity (PMCV)Topiramate-0.78395% Confidence Interval -1.2347 to -0.3314Slope of change in M/S over 52 wks
Body Mass Index (BMI)Placebo-0.153795% Confidence Interval -0.7461 to 0.4387Slope of change in BMI kg/m2 over 52wks
Body Mass Index (BMI)Topiramate-0.286595% Confidence Interval -0.8952 to 0.3221Slope of change in BMI kg/m2 over 52wks
Hemoglobin A1CPlacebo0.0395% Confidence Interval -0.0281 to 0.0880change in %/52 weeks over 96 weeks
Hemoglobin A1CTopiramate0.027995% Confidence Interval -0.0299 to 0.0858change in %/52 weeks over 96 weeks
Serum Triglycerides (TRG)Placebo0.02295% Confidence Interval -0.0258 to 0.0698change in mg/dl/52 weeks over 96 weeks
Serum Triglycerides (TRG)Topiramate-0.017695% Confidence Interval -0.0654 to 0.0301change in mg/dl/52 weeks over 96 weeks

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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