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Trial · NCT03153111

Results by group14

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent of Baseline N-terminal Pro-brain Natriuretic Peptide (NT-proBNP) Assessed at Week 24Macitentan108.39Geometric Coefficient of Variation 0.65percentage of baseline NT-proBNP
Percent of Baseline N-terminal Pro-brain Natriuretic Peptide (NT-proBNP) Assessed at Week 24Placebo106.27Geometric Coefficient of Variation 0.55percentage of baseline NT-proBNP
Change From Baseline to Week 24 in the Clinical Summary Score Assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ) ScoreMacitentan-2.37Standard Deviation 16.12score on a scale
Change From Baseline to Week 24 in the Clinical Summary Score Assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ) ScorePlacebo0.89Standard Deviation 17.72score on a scale
Change From Baseline to Week 24 in Accelerometer-assessed Proportion of Time Spent in Light to Vigourous Physical ActivityMacitentan-0.024Standard Deviation 0.084proportion of time spent
Change From Baseline to Week 24 in Accelerometer-assessed Proportion of Time Spent in Light to Vigourous Physical ActivityPlacebo-0.005Standard Deviation 0.098proportion of time spent
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksMacitentanWeek 1612Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksPlaceboWeek 165Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksMacitentanWeek 2414Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksPlaceboWeek 246Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksMacitentanWeek 3617Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksPlaceboWeek 369Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksMacitentanWeek 5218Participants
Number of Participants With Worsening of Heart Failure (WHF) Events Over 52 WeeksPlaceboWeek 5213Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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