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Trial · NCT03238235

Results by group132

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Mean Change From Baseline to Visit 11 in Total Fibrosis (%) on Log Scale, Comparing the Histology of Muscle BiopsiesGivinostat-0.01795% Confidence Interval -0.367 to 0.333log[percentage of total fibrosis]
Mean Change From Baseline to Visit 11 in Total Fibrosis (%) on Log Scale, Comparing the Histology of Muscle BiopsiesPlacebo-0.05495% Confidence Interval -0.507 to 0.399log[percentage of total fibrosis]
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Vastus Lateralis and SoleusGivinostatVastus Lateralis0.01795% Confidence Interval -0.053 to 0.086log[percentage of fat in muscle]
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Vastus Lateralis and SoleusPlaceboVastus Lateralis0.06495% Confidence Interval -0.019 to 0.147log[percentage of fat in muscle]
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Vastus Lateralis and SoleusGivinostatSoleus-4.28795% Confidence Interval -6.126 to -2.447log[percentage of fat in muscle]
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Vastus Lateralis and SoleusPlaceboSoleus-4.02195% Confidence Interval -6.404 to -1.637log[percentage of fat in muscle]
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesGivinostatWhole Thigh0.64295% Confidence Interval -0.328 to 1.611percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesPlaceboWhole Thigh1.99695% Confidence Interval 0.813 to 3.180percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesGivinostatQuadriceps0.61095% Confidence Interval -0.506 to 1.726percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesPlaceboQuadriceps2.57295% Confidence Interval 1.227 to 3.918percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesGivinostatHamstrings0.87795% Confidence Interval -0.627 to 2.381percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesPlaceboHamstrings1.45595% Confidence Interval -0.400 to 3.309percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesGivinostatTriceps Surae-0.27695% Confidence Interval -2.862 to 2.310percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesPlaceboTriceps Surae1.31795% Confidence Interval -1.686 to 4.319percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesGivinostatPelvis Girdle0.58495% Confidence Interval -0.509 to 1.676percentage of fat in muscle
Mean Change From Baseline to Visit 11 in the Percentage of Fat Fraction of Lower Limb MusclesPlaceboPelvis Girdle1.47195% Confidence Interval 0.112 to 2.830percentage of fat in muscle
Mean Change From Baseline to Visit 11 in Cross-sectional Area (CSA), in cm2 of Lower Limb MusclesGivinostatwhole thigh2.78295% Confidence Interval 0.151 to 5.413centimeters^2
Mean Change From Baseline to Visit 11 in Cross-sectional Area (CSA), in cm2 of Lower Limb MusclesPlacebowhole thigh2.37795% Confidence Interval -0.820 to 5.575centimeters^2
Mean Change From Baseline to Visit 11 in Cross-sectional Area (CSA), in cm2 of Lower Limb MusclesGivinostatquadriceps0.99795% Confidence Interval -0.169 to 2.163centimeters^2
Mean Change From Baseline to Visit 11 in Cross-sectional Area (CSA), in cm2 of Lower Limb MusclesPlaceboquadriceps1.08295% Confidence Interval -0.329 to 2.494centimeters^2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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