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Trial · NCT03292016

Results by group81

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Maximum Observed Plasma Concentration (Cmax)APL-130277, Sublingual Thin Film0.28190% Confidence Interval 0.191 to 0.413(ng/mL)/(mg)
Maximum Observed Plasma Concentration (Cmax)Subcutaneous APOKYN2.2990% Confidence Interval 1.46 to 3.59(ng/mL)/(mg)
Maximum Observed Plasma Concentration (Cmax)Subcutaneous APO-go2.7490% Confidence Interval 1.82 to 4.13(ng/mL)/(mg)
Observed Time of the Maximum Concentration (Tmax)APL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg0.75Full Range 0.52 to 0.75hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APOKYNAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg0.38Full Range 0.25 to 0.50hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APO-goAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg0.38Full Range 0.25 to 0.50hour
Observed Time of the Maximum Concentration (Tmax)APL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg0.63Full Range 0.25 to 1.02hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APOKYNAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg0.25Full Range 0.25 to 0.25hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APO-goAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg0.26Full Range 0.25 to 0.27hour
Observed Time of the Maximum Concentration (Tmax)APL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg0.75Full Range 0.50 to 1.00hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APOKYNAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg0.38Full Range 0.25 to 0.50hour
Observed Time of the Maximum Concentration (Tmax)Subcutaneous APO-goAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg0.25Full Range 0.25 to 0.50hour
Area Under the Concentration- Time Curve (AUC Last)APL-130277, Sublingual Thin Film0.50090% Confidence Interval 0.344 to 0.726(hxng/mL)/(mg)
Area Under the Concentration- Time Curve (AUC Last)Subcutaneous APOKYN2.9190% Confidence Interval 1.97 to 4.30(hxng/mL)/(mg)
Area Under the Concentration- Time Curve (AUC Last)Subcutaneous APO-go3.0090% Confidence Interval 2.05 to 4.39(hxng/mL)/(mg)
Area Under the Concentration- Time Curve (AUC Inf)APL-130277, Sublingual Thin Film0.5290% Confidence Interval 0.36 to 0.76(hxng/mL)/(mg)
Area Under the Concentration- Time Curve (AUC Inf)Subcutaneous APOKYN2.9790% Confidence Interval 2.01 to 4.39(hxng/mL)/(mg)
Area Under the Concentration- Time Curve (AUC Inf)Subcutaneous APO-go3.0490% Confidence Interval 2.08 to 4.45(hxng/mL)/(mg)
Mean Residence Time (MRT)APL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg1.69Geometric Coefficient of Variation 5.2h
Mean Residence Time (MRT)Subcutaneous APOKYNAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg1.44Geometric Coefficient of Variation 4.3h

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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