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Trial · NCT03292016

Results by group81

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Mean Residence Time (MRT)Subcutaneous APO-goAPL 20 mg, APOKYN 3 mg, and APO-go 3 mg1.21Geometric Coefficient of Variation 19.3h
Mean Residence Time (MRT)APL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg1.83Geometric Coefficient of Variation 41.5h
Mean Residence Time (MRT)Subcutaneous APOKYNAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg1.70Geometric Coefficient of Variation 13.8h
Mean Residence Time (MRT)Subcutaneous APO-goAPL 25 mg, APOKYN 4 mg, and APO-go 4 mg1.51Geometric Coefficient of Variation 19.0h
Mean Residence Time (MRT)APL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg2.15Geometric Coefficient of Variation 15.9h
Mean Residence Time (MRT)Subcutaneous APOKYNAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg1.23Geometric Coefficient of Variation 3.4h
Mean Residence Time (MRT)Subcutaneous APO-goAPL 30 mg, APOKYN 5 mg, and APO-go 5 mg1.08Geometric Coefficient of Variation 35.4h
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxAPL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg and APO-go 3 mg61.6Geometric Coefficient of Variation 28.8no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APOKYNAPL 20 mg, APOKYN 3 mg and APO-go 3 mg15.2Geometric Coefficient of Variation 48.9no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APO-goAPL 20 mg, APOKYN 3 mg and APO-go 3 mg11.5Geometric Coefficient of Variation 4.0no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxAPL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg and APO-go 4 mg32.0Geometric Coefficient of Variation 157.1no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APOKYNAPL 25 mg, APOKYN 4 mg and APO-go 4 mg9.0Geometric Coefficient of Variation 149.3no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APO-goAPL 25 mg, APOKYN 4 mg and APO-go 4 mg7.1Geometric Coefficient of Variation 240.3no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxAPL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg and APO-go 5 mg61.2Geometric Coefficient of Variation 87.0no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APOKYNAPL 30 mg, APOKYN 5 mg and APO-go 5 mg13.7Geometric Coefficient of Variation 8.2no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -CmaxSubcutaneous APO-goAPL 30 mg, APOKYN 5 mg and APO-go 5 mg11.3Geometric Coefficient of Variation 47.6no unit
Apparent Total Clearance of the Drug From Plasma After Oral Administration (CL/F)APL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg and APO-go 3 mg2766.9Geometric Coefficient of Variation 52.4L/h
Apparent Total Clearance of the Drug From Plasma After Oral Administration (CL/F)Subcutaneous APOKYNAPL 20 mg, APOKYN 3 mg and APO-go 3 mg407.9Geometric Coefficient of Variation 33.3L/h
Apparent Total Clearance of the Drug From Plasma After Oral Administration (CL/F)Subcutaneous APO-goAPL 20 mg, APOKYN 3 mg and APO-go 3 mg375.6Geometric Coefficient of Variation 32.2L/h
Apparent Total Clearance of the Drug From Plasma After Oral Administration (CL/F)APL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg and APO-go 4 mg1097.8Geometric Coefficient of Variation 99.5L/h

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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