Trial · NCT03548220
Results by group47
Each measurement the trial posted, group by group, in the words and numbers it posted.
1 to 20 of 47
Download this page as JSON| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Percentage of Participants Achieving a Hemoglobin (Hb) Response (HR) | Placebo Comparator: Placebo | 0 | percentage of participants | ||
| Percentage of Participants Achieving a Hemoglobin (Hb) Response (HR) | Experimental: AG-348 | 40.0 | percentage of participants | ||
| Average Change From Baseline in Hb Concentration at Weeks 16, 20 and 24 | Placebo Comparator: Placebo | -1.48 | Standard Error 2.082 | grams per liter (g/L) | |
| Average Change From Baseline in Hb Concentration at Weeks 16, 20 and 24 | Experimental: AG-348 | 16.73 | Standard Error 2.075 | grams per liter (g/L) | |
| Maximum Change From Baseline in Hb Concentration | Placebo Comparator: Placebo | 4.76 | Standard Deviation 4.217 | g/L | |
| Maximum Change From Baseline in Hb Concentration | Experimental: AG-348 | 23.94 | Standard Deviation 21.367 | g/L | |
| Time to Achieve an Increase in Hb Concentration of 1.5 g/dL or More | Experimental: AG-348 | 7.66 | Standard Deviation 4.050 | weeks | |
| Average Change From Baseline in Indirect Bilirubin at Weeks 16, 20 and 24 | Placebo Comparator: Placebo | 5.10 | Standard Error 4.061 | micromoles per liter (μmol/L) | |
| Average Change From Baseline in Indirect Bilirubin at Weeks 16, 20 and 24 | Experimental: AG-348 | -21.16 | Standard Error 4.228 | micromoles per liter (μmol/L) | |
| Average Change From Baseline in Lactic Acid Dehydrogenase (LDH) at Weeks 16, 20 and 24 | Placebo Comparator: Placebo | -21.18 | Standard Error 16.040 | units per litre (U/L) | |
| Average Change From Baseline in Lactic Acid Dehydrogenase (LDH) at Weeks 16, 20 and 24 | Experimental: AG-348 | -91.99 | Standard Error 16.222 | units per litre (U/L) | |
| Average Change From Baseline in Haptoglobin at Weeks 16, 20 and 24 | Placebo Comparator: Placebo | 0.012 | Standard Error 0.0412 | g/L | |
| Average Change From Baseline in Haptoglobin at Weeks 16, 20 and 24 | Experimental: AG-348 | 0.169 | Standard Error 0.0408 | g/L | |
| Average Change From Baseline in Reticulocyte Percentages at Weeks 16, 20 and 24 | Placebo Comparator: Placebo | 0.0038 | Standard Error 0.01390 | Reticulocyte percentages | |
| Average Change From Baseline in Reticulocyte Percentages at Weeks 16, 20 and 24 | Experimental: AG-348 | -0.0973 | Standard Error 0.01401 | Reticulocyte percentages | |
| Change From Baseline in Pyruvate Kinase Deficiency Diary (PKDD) Score at Week 24 | Placebo Comparator: Placebo | -2.05 | Standard Error 0.976 | score on a scale | |
| Change From Baseline in Pyruvate Kinase Deficiency Diary (PKDD) Score at Week 24 | Experimental: AG-348 | -5.16 | Standard Error 0.955 | score on a scale | |
| Change From Baseline in Pyruvate Kinase Deficiency Impact Assessment (PKDIA) Score at Week 24 | Placebo Comparator: Placebo | -1.39 | Standard Error 1.157 | score on a scale | |
| Change From Baseline in Pyruvate Kinase Deficiency Impact Assessment (PKDIA) Score at Week 24 | Experimental: AG-348 | -4.65 | Standard Error 1.123 | score on a scale | |
| Percentage of Participants With Adverse Events | Placebo Comparator: Placebo | 89.7 | percentage of participants |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT03548220/results