Trial · NCT03765398

VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment

NCT03765398, Not applicable, Completed, University of Illinois Chicago; results first posted 2025-07-03

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment. Trials, record NCT03765398. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03765398

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment
NCT number: NCT03765398
Status: Completed
Phases: Not applicable
Enrollment: 27 participants, actual
Lead sponsor: University of Illinois Chicago
Conditions: Mild Cognitive Impairment
Interventions: VR Cognitive-motor-balance training
First posted: 2018-12-05
Last updated: 2025-07-03
Results first posted: 2025-07-03

Source ClinicalTrials.gov

Registered outcomes24

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Change in Maximum Excursion	Baseline (Week 0) and Immediate Post-training (Week 5)	It is the actual magnitude of a self-initiated movement (i.e., how far did he/she actually reach a target) without taking a step or losing balance measured in percentage under single and dual-task conditions. Higher values indicate better performance.
Primary	Change in 4 Meter Walk Test	Baseline (Week 0) and Immediate Post-training (Week 5)	The total time taken to complete the 4 meters will be noted. Speed will then be determined by using the formula distance (4 meters) covered by time taken to complete the test. Higher speed indicate better performance.
Primary	Change of Accuracy in Letter Number Sequencing	Baseline (Week 0) and Immediate Post-training (Week 5)	This is an oral trail making test which includes listing alternate letter and number from the cue given in sequence. This test will be performed under single and dual-task conditions. For the auditory clock test, the participant is provided with cues that include different times of the day (e.g., 3.15) and the participant has to answer a yes if the hour and the minute hand of the clock are on the same side and no if the hour and minute hand are on opposite side of the clock. For the letter number sequencing test, the participant will be provided sets of letters and numbers (e.g.., A1) and will be asked to list in sequence the consecutive letter and numbers (e.g., B2, C3, D4, E5) until the next cue is provided. The performance will be measured in terms of accuracy (number of correct responses out of the total responses) for both the tests. Higher accuracy i.e., higher percentage indicates better performance.
Primary	Change in Working Memory	Baseline (Week 0) and Immediate Post-training (Week 5)	List Sorting Memory test to evaluate working memory. This test requires the participant to recall and sequentially list the visually and orally presented stimuli. The accuracy of the participants response is computer generated. Higher value indicate better performance. The total possible responses are 28.
Primary	Change in Episodic Memory	Baseline (Week 0) and Immediate Post-training (Week 5)	Picture sequence memory test will assess episodic memory of the individual. The number of adjacent pairs of pictures placed correctly will score a point. The scores are computer generated. Higher value indicate better performance.
Primary	Change in Accuracy of Flanker Inhibitory Control and Attention Test	Baseline (Week 0) and Immediate Post-training (Week 5)	Flanker inhibitory control and attention test is used to evaluate the participants ability to inhibit the attention to the stimulus flanking it and focus on a particular stimulus. Accuracy of the responses are recorded and the scores are computer generated. Higher value indicate better performance.
Primary	Change in Cognitive Flexibility and Attention	Baseline (Week 0) and Immediate Post-training (Week 5)	Dimensional Change card sort assesses cognitive flexibility and attention. Participants are asked to match a series of bivalent pictures either by colors or shapes accordingly. Responses are computer recorded and accuracy scores are computer generated. Higher value indicate better performance.
Primary	Change in Processing Speed	Baseline (Week 0) and Immediate Post-training (Week 5)	Pattern comparison processing speed test is used to evaluate the processing speed. The participants are expected to respond whether the two pictures side-by side are same or not the same. Accuracy will be recorded by the number of correct responses out of the total questions in 90 seconds. Scores are computer generated. Higher value indicate better performance.
Secondary	Change in Movement Velocity	Baseline (Week 0) and Immediate post-training (Week 5)	It is the average speed of center of gravity movement during intentional movement measured in degrees per second under single and dual-task conditions. Higher values indicate better performance.
Secondary	Changes in End Point Excursion	Baseline (Week 0) and post-training (Week 5)	It is the magnitude of a self-initiated movement (i.e., how far he/she wills to reach a target) without taking a step or losing balance measured in percentage under single and dual-task conditions. Higher values indicate better performance.

1 to 10 of 24Source ClinicalTrials.gov

See all 24 registered outcomes

Outcomes24

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Change in Maximum Excursion	Baseline (Week 0) and Immediate Post-training (Week 5)		percentage of center of pressure motion	MEAN
PRIMARY	Change in 4 Meter Walk Test	Baseline (Week 0) and Immediate Post-training (Week 5)		m/s	MEAN
PRIMARY	Change of Accuracy in Letter Number Sequencing	Baseline (Week 0) and Immediate Post-training (Week 5)		percentage of total responses	MEAN
PRIMARY	Change in Working Memory	Baseline (Week 0) and Immediate Post-training (Week 5)		correct responses	MEAN
PRIMARY	Change in Episodic Memory	Baseline (Week 0) and Immediate Post-training (Week 5)		accuracy (%)	MEAN
PRIMARY	Change in Accuracy of Flanker Inhibitory Control and Attention Test	Baseline (Week 0) and Immediate Post-training (Week 5)		% accurate	MEAN
PRIMARY	Change in Cognitive Flexibility and Attention	Baseline (Week 0) and Immediate Post-training (Week 5)		% accurate	MEAN
PRIMARY	Change in Processing Speed	Baseline (Week 0) and Immediate Post-training (Week 5)		percentage of accurate responses	MEAN
SECONDARY	Change in Movement Velocity	Baseline (Week 0) and Immediate post-training (Week 5)	Due to the emergence of the COVID-19 pandemic, this study was conducted primarily on Zoom, preventing the collection of data for this outcome measure, as the assessment is typically conducted in person.
SECONDARY	Changes in End Point Excursion	Baseline (Week 0) and post-training (Week 5)	Due to the emergence of the COVID-19 pandemic, this study was conducted primarily on Zoom, preventing the collection of data for this outcome measure, as the assessment is typically conducted in person.

1 to 10 of 24Source ClinicalTrials.gov

See all 24 outcomes

Results by group46

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Spread	Units
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in forward Direction, Pre-Training	80.9	Standard Deviation 13.8	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Forward Direction, Post-Training	86.5	Standard Deviation 15	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Backward Direction, Pre-Training	66.8	Standard Deviation 17.7	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Backward Direction, Post-Training	80.9	Standard Deviation 11.8	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Left Direction, Pre-Training	80.7	Standard Deviation 11.0	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Left Direction, Post-Training	87.1	Standard Deviation 5.3	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Right Direction, Pre-Training	76.4	Standard Deviation 11.2	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Right Direction, Post-Training	87.3	Standard Deviation 6.9	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Forward Direction while performing auditory clock test, Pre-Training	72.0	Standard Deviation 23.6	percentage of center of pressure motion
Change in Maximum Excursion	VR Cognitive-motor-balance Training	Maximum excursion in Forward Direction while performing auditory clock test, Post-Training	84.2	Standard Deviation 17.4	percentage of center of pressure motion

1 to 10 of 46Source ClinicalTrials.gov

See all 46 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Baseline Measurements	STARTED	VR Cognitive-motor-balance Training	18
Baseline Measurements	COMPLETED	VR Cognitive-motor-balance Training	14
Baseline Measurements	NOT COMPLETED	VR Cognitive-motor-balance Training	4
Intervention	STARTED	VR Cognitive-motor-balance Training	14
Intervention	COMPLETED	VR Cognitive-motor-balance Training	10
Intervention	NOT COMPLETED	VR Cognitive-motor-balance Training	4

Source ClinicalTrials.gov

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals3

The totals the trial posted for each group.

Total	Group	At risk
Total, all-cause mortality	VR Cognitive-motor-balance Training	27
Total, other adverse events	VR Cognitive-motor-balance Training	27
Total, serious adverse events	VR Cognitive-motor-balance Training	27

Source ClinicalTrials.gov

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

Project	Title	Principal investigators	Organization	Funder	Fiscal years
P30AG022849	Midwest Roybal Center for Health Promotion and Translation	BHATT, TANVI; MARQUEZ, DAVID X	UNIVERSITY OF ILLINOIS AT CHICAGO	NATIONAL INSTITUTE ON AGING	2003 to 2025

Source NIH RePORTER

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests7

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

Test	Named as	Source
Dimensional Change Card Sort	Primary outcome	ConductCognition
Letter-Number Sequencing Task	Primary outcome	ConductCognition
Pattern and Letter Comparison	Primary outcome	ConductCognition
Picture Order Memory Test	Primary outcome	ConductCognition
Trail Making Test A	Primary outcome	ConductCognition
Trail Making Test B	Primary outcome	ConductCognition
Stroop Color-Word Test	Secondary outcome	ConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03765398

GET https://conductscience.org/api/trials/v1/NCT03765398/registered?page=2

API reference For AI assistants