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Trial · NCT03774446

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryNumber of participants with a normalized 24-hour urinary free cortisol (UFC) at study completion4 weeks
PrimaryNumber of participants with UFC above the upper limit of normal (ULN) but reduced by ≥50% from baseline at study completion4 weeks
SecondaryPlasma adrenocorticotrophic hormoneBaseline and week 4
SecondarySalivary cortisolBaseline and week 4
SecondarySerum cortisolBaseline and week 4
SecondaryGlycated hemoglobin (HbA1c)Baseline and week 4
SecondaryFasting blood glucoseBaseline and week 4
SecondaryWeight and height to report body mass index (BMI) in kg/m^2Baseline and week 4
SecondaryBlood pressureBaseline and week 4
SecondaryChange on visual field examBaseline and week 4
SecondaryChange in tumor size on pituitary MRIBaseline and week 4
SecondaryChange in quality of life measured using the CushingQOL questionnaireBaseline and week 4
SecondaryNumber of treatment-emergent adverse events graded using the National Cancer Institute (NCI) Common Toxicity Criteria (CTC) version 4.0Baseline and week 4

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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