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Trial · NCT03805100

Results by group34

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change in Best Corrected Visual Acuity (BCVA)Xlucane (Proposed Ranibizumab Biosimilar)4.5795% Confidence Interval 3.54 to 5.61Letters
Change in Best Corrected Visual Acuity (BCVA)Lucentis (Ranibizumab)6.3795% Confidence Interval 5.31 to 7.42Letters
Change From Baseline in the Total Size of Choroidal Neovascular Leakage Area in the Study EyeXlucane (Proposed Ranibizumab Biosimilar)-4.0995% Confidence Interval -4.66 to -3.52mm2
Change From Baseline in the Total Size of Choroidal Neovascular Leakage Area in the Study EyeLucentis (Ranibizumab)-3.7195% Confidence Interval -4.28 to -3.14mm2
Change From Baseline in the Total Size of Choroidal Neovascularisation in the Study EyeXlucane (Proposed Ranibizumab Biosimilar)-1.6295% Confidence Interval -2.19 to -1.05mm2
Change From Baseline in the Total Size of Choroidal Neovascularisation in the Study EyeLucentis (Ranibizumab)-1.1195% Confidence Interval -1.68 to -0.54mm2
Central Foveal Thickness in the Study EyeXlucane (Proposed Ranibizumab Biosimilar)-117.4495% Confidence Interval -125.33 to 109.55um
Central Foveal Thickness in the Study EyeLucentis (Ranibizumab)-115.1495% Confidence Interval -123.14 to -107.14um
Percentage of Subjects With Loss of <15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Missing at random (MAR)94.8percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersLucentis (Ranibizumab)Missing at random (MAR)96.0percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Missing completely at random (MCAR)94.9percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersLucentis (Ranibizumab)Missing completely at random (MCAR)96.1percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Missing not at random (MNAR)94.8percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersLucentis (Ranibizumab)Missing not at random (MNAR)96.1percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Composite (Missing and non-evaluable data are classed as no response)68.8percentage of responders
Percentage of Subjects With Loss of <15 BCVA LettersLucentis (Ranibizumab)Composite (Missing and non-evaluable data are classed as no response)67.6percentage of responders
Percentage of Subjects With Gain of ≥15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Missing at random (MAR)23.6percentage of responders
Percentage of Subjects With Gain of ≥15 BCVA LettersLucentis (Ranibizumab)Missing at random (MAR)29.7percentage of responders
Percentage of Subjects With Gain of ≥15 BCVA LettersXlucane (Proposed Ranibizumab Biosimilar)Missing completely at random (MCAR)23.2percentage of responders
Percentage of Subjects With Gain of ≥15 BCVA LettersLucentis (Ranibizumab)Missing completely at random (MCAR)28.8percentage of responders

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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